[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100556483":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":22,"centralContacts":27,"locations":36,"responsibleParty":58,"collaborators":62,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":10,"eligibilityCriteria":71,"healthyVolunteers":67,"sex":72,"minAge":10,"maxAge":10,"enrollmentInfo":73,"targetDuration":10,"studyType":76,"phases":10,"briefSummary":77,"conditions":78,"keywords":82,"overallStatus":39,"whyStopped":10,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"National and Kapodistrian University of Athens","OTHER",[8,13],{"label":9,"type":10,"description":9,"interventionNames":11},"Postmenopausal Female Patient with subcapital hip osteoporotic fracture",null,[12],"Other: Bone, Serum and Plasma sample",{"label":14,"type":10,"description":15,"interventionNames":16},"Postmenopausal Female Patient with hip osteoarthritis","Postmenopausal female patient with hip osteoarthritis who will undergo total hip replacement.",[12],[18],{"type":6,"name":19,"description":20,"armGroupLabels":21,"otherNames":10},"Bone, Serum and Plasma sample","Intervention: Bone samples will be collected during surgery from the femoral neck (which is typically removed and discarded in these operations) and fasting morning blood samples.",[14,9],[23],{"name":24,"affiliation":25,"role":26},"Efstathios Chronopoulos","KAT General Hospital, Athens Greece","STUDY_DIRECTOR",[28,32],{"name":24,"role":29,"phone":30,"phoneExt":10,"email":31},"CONTACT","00306944837793","stathi24@yahoo.gr",{"name":33,"role":29,"phone":34,"phoneExt":10,"email":35},"Stavros Lykos","00306978695466","lykosstavros@gmail.com",[37],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Laboratory for Research of the Musculoskeletal System","RECRUITING","Kifissia","Attica","14561","Greece","GR",{"type":46,"coordinates":47},"Point",[48,49],23.81106,38.07438,{"lat":49,"lon":48},[52,54,56],{"name":53,"role":29,"phone":30,"phoneExt":10,"email":31},"Efstathios Chronopoulos, Prof.",{"name":33,"role":55,"phone":10,"phoneExt":10,"email":10},"SUB_INVESTIGATOR",{"name":57,"role":55,"phone":10,"phoneExt":10,"email":10},"Kalliopi Lampropoulou-Adamidou",{"type":59,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","EFSTATHIOS CHRONOPOULOS","Professor in Orthopedics at National and Kapodistrian University of Athens, Laboratory for Research of the Musculoskeletal System Director",[63],{"name":64,"class":6},"National Hellenic Research Foundation","100556483","new-biomarkers-and-therapeutic-targets-in-osteoporosis-via-omics-technologies-100556483",false,"NCT06525688","New Biomarkers and Therapeutic Targets in Osteoporosis Via Omics Technologies","Identification of New Biomarkers and Potential Therapeutic Targets in Clinical Osteoporosis Using Omics Technologies","Inclusion Criteria:\n\n* Postmenopausal Female Patients with osteoporotic subcapital femoral neck fracture (Arm 1)\n* Postmenopausal Female Patients with hip osteoarthritis that will undergo Total Hip Replacement (Arm 2)\n\nExclusion Criteria:\n\n* Patients that have undergone before osteoporotic fractures\n* Patients with severe cardiovascular, pulmonary, autoimmune, or urinary system conditions","FEMALE",{"count":74,"type":75},60,"ESTIMATED","OBSERVATIONAL","This study aims to discover novel biomarkers and therapeutic targets for osteoporosis through the use of advanced omics technologies, including proteomics and metabolomics. By analyzing bone and plasma samples from patients with osteoporosis, the research seeks to understand the underlying mechanisms of the disease and identify potential diagnostic and therapeutic biomarkers.",[79,80,81],"Osteoporosis, Postmenopausal","Osteoporosis Fracture","Osteoporosis, Severe",[83,84,85,86,87,88,89],"Osteoporosis","Osteoarthritis","Hip fracture","Postmenopausal Osteoporosis","Proteomics","Metabolomics","Osteoporotic Hip Fracture","2024-07-24",{"date":92,"type":93},"2024-07-29","ACTUAL",{"date":95,"type":93},"2024-07-03",{"date":97,"type":75},"2025-12-30",{"name":5,"class":6},1]