[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100553867":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":26,"centralContacts":30,"locations":38,"responsibleParty":53,"collaborators":10,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":10,"eligibilityCriteria":62,"healthyVolunteers":63,"sex":64,"minAge":65,"maxAge":10,"enrollmentInfo":66,"targetDuration":10,"studyType":69,"phases":10,"briefSummary":70,"conditions":71,"keywords":10,"overallStatus":41,"whyStopped":10,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"Sohag University","OTHER",[8,14],{"label":9,"type":10,"description":9,"interventionNames":11},"Elevated NLR and CRP level",null,[12,13],"Diagnostic Test: CBC","Diagnostic Test: C-reactive protein",{"label":15,"type":10,"description":9,"interventionNames":16},"Normal NLR and CRP level",[12,13],[18,23],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"DIAGNOSTIC_TEST","CBC","Explore the role of Neutrophil-lymphocyte ratio C-reactive protein in predicting the imediate and short-term prognosis in ST-segment elevation myocardial infarction",[9,15],{"type":19,"name":24,"description":21,"armGroupLabels":25,"otherNames":10},"C-reactive protein",[9,15],[27],{"name":28,"affiliation":5,"role":29},"Magdy M Amin, Professor","PRINCIPAL_INVESTIGATOR",[31,36],{"name":32,"role":33,"phone":34,"phoneExt":10,"email":35},"Albair Y Kaiser, Resident","CONTACT","01010095136","Alberyouseef@med.edu.eg",{"name":37,"role":33,"phone":10,"phoneExt":10,"email":10},"Sharaf El-DEEN Sh Abd-Allah, Professor",[39],{"facility":40,"status":41,"city":42,"state":10,"zip":10,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Sohag university hospital","RECRUITING","Sohag","Egypt","EG",{"type":46,"coordinates":47},"Point",[48,49],31.69478,26.55695,{"lat":49,"lon":48},[52],{"name":28,"role":33,"phone":10,"phoneExt":10,"email":10},{"type":29,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Albier Youssef Kaiser","Resident at Internal Medicine Department Sohag University hospital","100553867","nlr-and-crp-useful-as-cost-effective-preliminary-prognostic-markers-in-st-elevation-myocardial-infarction-100553867",false,"NCT06491667","NLR AND CRP Useful as Cost-Effective Preliminary Prognostic Markers in ST-Elevation Myocardial Infarction","Neutrophil-to-Lymphocyte Ratio AND C-REATIVE PROTEIN Useful as Cost-Effective Preliminary Prognostic Markers in ST-Elevation Myocardial Infarction","Inclusion Criteria:\n\n* Patients with age ≥18 years of either sex, with either increase in serum cardiac biomarkers or ECG are STEMI.\n\nExclusion Criteria:\n\n* Patients presenting with NSTEMI and unstable angina\n* Patients with any of these associated conditions that can affect NLR or CRP including\n* Inflammatory conditions such as collagen-vascular disorders\n* Acute or chronic infectious diseases.\n* Auto-immune and neoplastic diseases.\n* Chronic hepatic diseases.\n* Renal failure.\n* Thyroid disorders.\n* Previous valvular heart disease.",true,"ALL","18 Years",{"count":67,"type":68},100,"ESTIMATED","OBSERVATIONAL","Acute myocardial infarction (AMI) is a serious and fatal cardiovascular emergency and considered the leading cause of mortality worldwide.\n\nAtherosclerosis of coronary arteries which takes decades to manifest clinically, is the primary predisposing pathologic factor responsible for the development of coronary heart disease It has been shown that A complex immune and inflammatory pathophysiological process is thought to be crucial for in the initiation and progression of atherosclerotic plaques.\n\nInflammation is one of the main mechanisms in the pathogenesis of atherosclerosis , Destabilization of chronic artery plaques and development of thrombosis, which are the main mechanisms in the pathophysiology of ST-segment elevation myocardial infarction (STEMI).\n\n, and the interest to the evaluation of inflammatory biomarkers in coronary artery disease (CAD) has been increasing over the last decade .\n\nAlthough numerous inflammatory markers, including troponin T\u002FI, lactate dehydrogenase (LDH), and creatine kinase (CK-MB), are linked to worsened clinical outcomes in both ST elevation and non-ST elevation myocardial infarction (NSTEMI), there is an unmet need for a cost-effective biomarker for impoverished countries of the world .\n\nThe neutrophil-to-lymphocyte ratio (NLR), and C-reactive protein (CRP) ; has emerged as an important inflammatory markers for cardiovascular risk stratification.\n\nAnd are relatively cheap inflammatory markers, can act as a bridge to mitigate the gap in assessing the cardiovascular risk and outcomes",[72],"STEMI","2024-07-08",{"date":75,"type":76},"2024-07-09","ACTUAL",{"date":78,"type":76},"2024-07-01",{"date":80,"type":68},"2024-12-01",{"name":5,"class":6},1]