[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100608384":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":12,"centralContacts":19,"locations":7,"responsibleParty":25,"collaborators":7,"id":29,"slug":30,"hasResults":31,"nctId":32,"briefTitle":33,"officialTitle":34,"acronym":35,"eligibilityCriteria":36,"healthyVolunteers":31,"sex":37,"minAge":38,"maxAge":7,"enrollmentInfo":39,"targetDuration":42,"studyType":43,"phases":7,"briefSummary":44,"conditions":45,"keywords":7,"overallStatus":51,"whyStopped":7,"lastUpdateSubmitDate":52,"lastUpdatePostDateStruct":53,"startDateStruct":56,"completionDateStruct":57,"leadSponsor":59,"locationsCount":7},{"fullName":5,"class":6},"Assiut University","OTHER",null,[9],{"type":6,"name":10,"description":11,"armGroupLabels":7,"otherNames":7},"Nocturnal Blood Pressure Dipping","Patients will be classified as dippers (≥10% nocturnal BP fall) or non-dippers (\\\u003C10% nocturnal BP fall) based on 24-hour ambulatory blood pressure monitoring.",[13,17],{"name":14,"affiliation":15,"role":16},"Mohamed Aboel-Kassem Farghal Abdelmegid","Cardiology Department - Assiut University","STUDY_CHAIR",{"name":18,"affiliation":15,"role":16},"Noha Mohamed Gamal Hashem",[20],{"name":21,"role":22,"phone":23,"phoneExt":7,"email":24},"Amr Abdelwahab Hussein Ahmed, MBBCh","CONTACT","01009692938","Amr.17289535@med.aun.edu.eg",{"type":26,"investigatorFullName":27,"investigatorTitle":28,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Amr Abdelwahab Hussein Ahmed","Dr","100608384","nocturnal-blood-pressure-dipping-and-ventricular-repolarization-in-hypertension-100608384",false,"NCT07200856","Nocturnal Blood Pressure Dipping and Ventricular Repolarization in Hypertension","Impact of Nocturnal Blood Pressure Dipping on Ventricular Repolarization in Hypertensive Patients","NBP-DIP","Inclusion Criteria:\n\n* Adults ≥18 years old\n* Diagnosed with essential hypertension\n* Completed 24-hour ambulatory blood pressure monitoring (ABPM)\n* Availability of good-quality 12-lead ECG\n* Availability of good-quality transthoracic echocardiography\n\nExclusion Criteria:\n\n* Body mass index (BMI) \\> 34.9 kg\u002Fm²\n* Atrial fibrillation or atrial flutter\n* Use of QT-prolonging medications\n* End-stage renal disease or liver failure\n* Bundle branch block or presence of pacemaker\n* Prior coronary revascularization (PCI or CABG)\n* Significant electrolyte imbalance","ALL","18 Years",{"count":40,"type":41},140,"ESTIMATED","1 Day","OBSERVATIONAL","The primary aim is to determine whether non-dipping status is associated with adverse repolarization markers and impaired myocardial mechanics compared to dipper hypertensive patients. Secondary analyses will compare these findings among resistant vs. non-resistant and controlled vs. uncontrolled hypertensive groups. This study may provide new insights into the prognostic significance of blood pressure dipping patterns in hypertensive patients.",[46,47,48,49,50],"Hypertension","Blood Pressure Monitoring, Ambulatory","Circadian Rhythm","Electrocardiography","Ventricular Function","NOT_YET_RECRUITING","2025-09-23",{"date":54,"type":55},"2025-10-01","ACTUAL",{"date":54,"type":41},{"date":58,"type":41},"2027-01-01",{"name":5,"class":6}]