[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100567668":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":23,"centralContacts":27,"locations":32,"responsibleParty":49,"collaborators":10,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":56,"acronym":10,"eligibilityCriteria":57,"healthyVolunteers":54,"sex":58,"minAge":10,"maxAge":10,"enrollmentInfo":59,"targetDuration":10,"studyType":62,"phases":10,"briefSummary":63,"conditions":64,"keywords":66,"overallStatus":35,"whyStopped":10,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"Shanghai 6th People's Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Difficult transoral and submental thyroidectomy",null,"(1) operative time more than 75% of the overall study cases (2) severe intraoperative vascular or recurrent laryngeal nerve injury",[13],"Other: Observations on clinicopathological factors influencing the difficulty of surgery",{"label":15,"type":10,"description":16,"interventionNames":17},"Normal transoral and submental thyroidectomy","the remaining of the entire study cases excluding the difficult cases",[13],[19],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"Observations on clinicopathological factors influencing the difficulty of surgery","Age, body mass index, gender, thyroid function parameters, lesion size, lesion location, ultrasound data",[9,15],[24],{"name":25,"affiliation":5,"role":26},"Ling Zhan, Doctor","PRINCIPAL_INVESTIGATOR",[28],{"name":25,"role":29,"phone":30,"phoneExt":10,"email":31},"CONTACT","08615821120972","rebecca0428zhan@163.com",[33],{"facility":34,"status":35,"city":36,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"Shanghai Sixth People's Hospital","RECRUITING","Shanghai","Shanghai Municipality","200233","China","CN",{"type":42,"coordinates":43},"Point",[44,45],121.45806,31.22222,{"lat":45,"lon":44},[48],{"name":25,"role":29,"phone":30,"phoneExt":10,"email":31},{"type":26,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Ling Zhan","Doctor","100567668","nomogram-for-predicting-difficult-transoral-and-submental-thyroidectomy-100567668",false,"NCT06671184","Nomogram for Predicting Difficult Transoral and Submental Thyroidectomy","Inclusion Criteria:\n\n* Clinical diagnosis of differentiated thyroid cancer with a maximum diameter not exceeding 4 cm\n* Absence of suspicious lateral lymph nodes or distant metastases\n* Participants with high cosmetic expectations\n* Participants who underwent total thyroidectomy and central lymph node dissection.\n\nExclusion Criteria:\n\n* Participants with fusion or fixation of lymph nodes in the neck\n* Participants with history of neck surgery or radiation\n* Participants with vocal fold fixation by preoperative fibrolaryngoscope\n* Participants with preoperative examination suggestive of extrathyroidal invasion\n* Participants with a significantly restricted neck","ALL",{"count":60,"type":61},500,"ESTIMATED","OBSERVATIONAL","No prior studies have stratified the difficulty of transoral and submental thyroidectomy (TOaST). The investigators aimed to investigate preoperative factors as indicators of difficult TOaSTs and to develop a predictive model accordingly.",[65],"Differentiated Thyroid Cancer",[67,68,69],"Differentiated thyroid cancer","Transoral and submental thyroidectomy","Surgical difficulty","2026-05-02",{"date":72,"type":73},"2026-05-07","ACTUAL",{"date":75,"type":73},"2021-01-01",{"date":77,"type":61},"2027-12-31",{"name":5,"class":6},1]