[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100510702":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":35,"locations":25,"responsibleParty":45,"collaborators":47,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":58,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":25,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":72,"overallStatus":78,"whyStopped":25,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":25},{"fullName":5,"class":6},"IRCCS National Neurological Institute \"C. Mondino\" Foundation","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental group","EXPERIMENTAL","The experimental group receives strategic memory training plus non-invasive brain stimulation (ACTIVE tDCS).",[13],"Other: Non-invasive brain stimulation",{"label":15,"type":16,"description":17,"interventionNames":18},"Control Group","SHAM_COMPARATOR","The control group receives strategic memory training plus sham non-invasive brain stimulation (SHAM tDCS).",[19],"Other: Sham non-invasive brain stimulation",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Non-invasive brain stimulation","ACTIVE transcranial direct current stimulation( tDCS)",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Sham non-invasive brain stimulation","SHAM tDCS",[15],[31],{"name":32,"affiliation":33,"role":34},"Stefano Cappa, MD","Dementia Research Center","PRINCIPAL_INVESTIGATOR",[36,41],{"name":37,"role":38,"phone":39,"phoneExt":25,"email":40},"Sara Bottiroli, Dc.","CONTACT","+39 0382 380201","sara.bottiroli@unipv.it",{"name":42,"role":38,"phone":43,"phoneExt":25,"email":44},"Cinzia Fattore, MD","+39 0382 380385","cinzia.fattore@mondino.it",{"type":46,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[48],{"name":49,"class":6},"University of Pavia","100510702","non-invasive-brain-stimulation-and-strategic-memory-training-100510702",false,"NCT05929872","Non-invasive Brain Stimulation and Strategic Memory Training","The Efficacy of Strategic Memory Training Coupled With Non-invasive Brain Stimulation Techniques in Healthy Aging Population and Subjective Cognitive Decline Patients: a Randomized-controlled Study","StMe-tDCS","Inclusion Criteria:\n\n* MMSE ≥ 24.\n* GDS \\\u003C e uguale 11.\n* Age between 65 and 85 years.\n* Educational level ≥ 5 years.\n\nExclusion Criteria:\n\n* Pre-existing cognitive impairment (e.g. aphasia, neglect).\n* Dementia.\n* Severe disturbances in consciousness.\n* Concomitant severe psychiatric disease or other neurological conditions (e.g. depression and behavioral disorders).\n* Motor or sensory diseases that may interfere with test execution or strategic memory training.",true,"ALL","65 Years","85 Years",{"count":63,"type":64},56,"ESTIMATED","INTERVENTIONAL",[67],"NA","Physiological aging is often associated with memory function decline. Recently, the use of transcranial direct current stimulation (tDCS), a type of non-invasive brain stimulation, has been combined with adaptive working memory training interventions in healthy older adults, providing evidence for a significant improvement in memory functions. To the best of our knowledge, no study addressed the use of strategic memory training coupled with the use of tDCS in normal aging. Strategic memory trainings allow to improve participants' performance in the practiced task and to generalize the use of memory strategies to new materials. This Randomized Controlled Trial (RCT) aims to evaluate the effectiveness of a combined intervention associating strategic memory training with the use of tDCS. Healthy older adults and participants with subjective cognitive decline will be recruited and randomly assigned to the experimental group (strategic memory training + ACTIVE tDCS) or the control group (strategic memory training + SHAM tDCS). All participants will be evaluated on transfer and practiced tasks before (T0) and after (T1) the treatment and during follow-up visits, scheduled at 1 month (T2) and 3 months (T3) after the intervention.",[70,71],"Cognitive Decline","Healthy Aging",[73,74,75,76,77],"Healthy aging","Subjective cognitive decline","Non-pharmacological treatments","Memory training","Transcranial direct current stimulation","NOT_YET_RECRUITING","2023-06-29",{"date":81,"type":82},"2023-07-03","ACTUAL",{"date":84,"type":64},"2023-07-30",{"date":86,"type":64},"2026-12-30",{"name":5,"class":6}]