[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100514216":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":45,"responsibleParty":67,"collaborators":26,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":26,"eligibilityCriteria":75,"healthyVolunteers":71,"sex":76,"minAge":77,"maxAge":26,"enrollmentInfo":78,"targetDuration":26,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":87,"overallStatus":48,"whyStopped":26,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"Western University, Canada","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Treatment group","EXPERIMENTAL","Participants of this group will receive active rTMS along with real FES cycling.",[13,14],"Device: repetitive transcranial magnetic stimulation (rTMS)","Device: functional electrical stimulation (FES) cycling",{"label":16,"type":17,"description":18,"interventionNames":19},"Control group","SHAM_COMPARATOR","Participants of this group will receive sham rTMS along with real FES cycling.",[14],[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","repetitive transcranial magnetic stimulation (rTMS)","rTMS will be applied to primary motor cortex of the brain.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"functional electrical stimulation (FES) cycling","FES will be applied to muscles associated in cycling: quadriceps, hamstrings, tibialis anterior, gastrocnemius, soleus.",[16,9],[32],{"name":33,"affiliation":5,"role":34},"Siobhan Schabrun, PhD","STUDY_DIRECTOR",[36,42],{"name":37,"role":38,"phone":39,"phoneExt":40,"email":41},"Janelle Unger, PhD","CONTACT","+1-519-646-6100","45789","janelle.unger@uwo.ca",{"name":43,"role":38,"phone":39,"phoneExt":26,"email":44},"Siobhan Schabrun, BSc","sschabru@uwo.ca",[46],{"facility":47,"status":48,"city":49,"state":50,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"Parkwood Institute","RECRUITING","London","Ontario","N6C 0A7","Canada","CA",{"type":55,"coordinates":56},"Point",[57,58],-81.23304,42.98339,{"lat":58,"lon":57},[61,63,65],{"name":37,"role":38,"phone":62,"phoneExt":40,"email":41},"+1-519-664-6100",{"name":64,"role":38,"phone":39,"phoneExt":26,"email":44},"Siobhan Scharbun, BSc",{"name":33,"role":66,"phone":26,"phoneExt":26,"email":26},"SUB_INVESTIGATOR",{"type":68,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100514216","non-invasive-brain-stimulation-paired-with-fes-cycling-post-sci-100514216",false,"NCT05975606","Non-invasive Brain Stimulation Paired With FES Cycling Post SCI","Exploring the Effect of Non-invasive Brain Stimulation Paired With Functional Electrical Stimulation to Improve Lower Extremity Function Following Incomplete Spinal Cord Injury","Inclusion Criteria:\n\n* adult\n* having motor incomplete SCI with level C or D on the American Spinal Injury Association Impairment Scale (AIS) with the lesion at any level of the cord resulting from either traumatic or non-traumatic etiology who are at least one-year post-injury.\n* having non-progressive SCI\n* being able to walk independently for 10 meters without help from another person\n\nExclusion Criteria:\n\n* other orthopedic or neurological implications that affect the lower extremity function\n* contraindications to FES (e.g., implanted electronic devices, unhealed bone fractures, sever contractures, extreme osteoporosis or osteoarthritis)\n* contraindications to rTMS (e.g., metal implants, history of seizure, cochlear implants)","ALL","18 Years",{"count":79,"type":80},14,"ESTIMATED","INTERVENTIONAL",[83],"NA","This project is randomized controlled trial which will explore the effect of pairing repetitive Transcranial Magnetic Stimulation (rTMS) with Functional Electrical Stimulation (FES) Cycling on lower extremity function in people with incomplete spinal cord injury and compare the effects to each one of these interventions alone.",[86],"Incomplete Spinal Cord Injury",[88,89,90,91,92,93,94],"incomplete spinal cord injury","repetitive transcranial magnetic stimulation","functional electrical stimulation cycling","lower extremity function","walking speed","muscle strength","feasibility","2025-04-09",{"date":97,"type":98},"2025-04-13","ACTUAL",{"date":100,"type":98},"2023-09-19",{"date":102,"type":80},"2025-12",{"name":5,"class":6},1]