[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100338258":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":22,"centralContacts":26,"locations":33,"responsibleParty":50,"collaborators":31,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":31,"eligibilityCriteria":58,"healthyVolunteers":54,"sex":59,"minAge":60,"maxAge":31,"enrollmentInfo":61,"targetDuration":31,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":74,"overallStatus":35,"whyStopped":31,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"University of Miami","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"IDH-Mutant Glioma Patients","EXPERIMENTAL","Patients who have suspected or confirmed gliomas and are scheduled to undergo biopsy or resection of their brain tumors will receive a 3 Tesla (3T) Magnetic Resonance Imaging (MRI) scan of their brain.",[13],"Device: 3T MRI Scanner",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DEVICE","3T MRI Scanner","3T MRI Scanner providing Mega-laser sequence for single-voxel Magnetic Resonance Spectroscopy (MRS) data for 2 hydroxyglutarate (2HG) quantitation.",[9],[21],"3 Tesla (3T) Magnetic Resonance Imaging Scanner",[23],{"name":24,"affiliation":5,"role":25},"Macarena De La Fuente, MD","PRINCIPAL_INVESTIGATOR",[27],{"name":28,"role":29,"phone":30,"phoneExt":31,"email":32},"Nathalie Padron","CONTACT","305-243-3530",null,"npadron@med.miami.edu",[34],{"facility":5,"status":35,"city":36,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"RECRUITING","Miami","Florida","33136","United States","US",{"type":42,"coordinates":43},"Point",[44,45],-80.19366,25.77427,{"lat":45,"lon":44},[48,49],{"name":28,"role":29,"phone":30,"phoneExt":31,"email":32},{"name":24,"role":25,"phone":31,"phoneExt":31,"email":31},{"type":25,"investigatorFullName":24,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"Assistance Professor","100338258","non-invasive-glioma-characterization-through-molecular-imaging-100338258",false,"NCT03684109","Non-invasive Glioma Characterization Through Molecular Imaging","Pilot Study for Non-invasive Glioma Characterization Through Molecular Imaging","Inclusion Criteria:\n\n* Adults (≥18 year old)\n* Subjects with suspected or confirmed gliomas and who will have a medically indicated biopsy or resection of his\u002Fher brain lesion.\n\nExclusion Criteria:\n\n* Adults unable to consent\n* Individuals who are not yet adults (infants, children, teenagers)\n* Pregnant women\n* Patients unable to have MRI done","ALL","18 Years",{"count":62,"type":63},30,"ESTIMATED","INTERVENTIONAL",[66],"NA","MRI-based sequences can provide non-invasive quantification of intratumoral 2-hydroxyglutarate (2HG) distribution and tumor cellularity in human gliomas and help guide the development of novel glioma therapies.",[69,70,71,72,73],"Glioma","Brain Tumor","Primary Brain Tumor","Malignant Glioma","Malignant Primary Brain Tumor",[75,76,77,78],"Non-invasive glioma characterization","Molecular Imaging","Isocitrate Dehydrogenase (IDH) Mutations","MRI-Based Sequencing","2026-04-14",{"date":81,"type":82},"2026-04-20","ACTUAL",{"date":84,"type":82},"2019-01-25",{"date":86,"type":63},"2027-01-31",{"name":5,"class":6},1]