[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100465387":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":25,"locations":30,"responsibleParty":114,"collaborators":10,"id":116,"slug":117,"hasResults":118,"nctId":119,"briefTitle":120,"officialTitle":121,"acronym":122,"eligibilityCriteria":123,"healthyVolunteers":118,"sex":124,"minAge":10,"maxAge":125,"enrollmentInfo":126,"targetDuration":10,"studyType":129,"phases":10,"briefSummary":130,"conditions":131,"keywords":133,"overallStatus":88,"whyStopped":10,"lastUpdateSubmitDate":137,"lastUpdatePostDateStruct":138,"startDateStruct":141,"completionDateStruct":143,"leadSponsor":145,"locationsCount":146},{"fullName":5,"class":6},"Azienda Ospedaliera di Padova","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"pediatric patients with ICP device",null,"In children requiring ICP, TCD and ONSD will be measured:\n\n* within 30 minutes before to the placement of the ICP (if possiblel)\n* at least twice a day after placement of the invasive ICP for the first 48 hours\n\nEach measurement will include:\n\n* The measure of the invasive ICP\n* Calculation of invasive CPP (invasive MAP-invasive ICP)\n* TCD: FVs, FVd, FVm, from which the nCPP will be obtained with the formula FVdICP. The nICP will be obtained from invasive MAP minus nCPP.\n* The measurement of the nICP ONSD (2) for a total of 2 measurements preferably from the side where the invasive ICP device is positioned.\n\nMeasurements (TCD and ONSD) will be done by two operators blinded by each other in order to evaluate the inter-operator variability",[13],"Device: bedside sonography",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DEVICE","bedside sonography","TCD and ONSD sonography twice a day per 2 days",[9],[21],{"name":22,"affiliation":23,"role":24},"angela amigoni, MD","University Hospital of Padova","PRINCIPAL_INVESTIGATOR",[26],{"name":22,"role":27,"phone":28,"phoneExt":10,"email":29},"CONTACT","+39 339 8333765","angela.amigoni@aopd.veneto.it",[31,49,60,73,86,103],{"facility":32,"status":33,"city":34,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"PICU IRCSS Sant'Orsola Malpighi","NOT_YET_RECRUITING","Bologna","Italy","IT",{"type":38,"coordinates":39},"Point",[40,41],11.33875,44.49381,{"lat":41,"lon":40},[44,46],{"name":45,"role":27,"phone":10,"phoneExt":10,"email":10},"matilde santià",{"name":47,"role":48,"phone":10,"phoneExt":10,"email":10},"fabio caramelli","SUB_INVESTIGATOR",{"facility":50,"status":33,"city":51,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":52,"geoPoint":56,"contacts":57},"PICU Spedali Civili BRescia","Brescia",{"type":38,"coordinates":53},[54,55],10.21472,45.53558,{"lat":55,"lon":54},[58],{"name":59,"role":27,"phone":10,"phoneExt":10,"email":10},"diego franchini",{"facility":61,"status":33,"city":62,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":63,"geoPoint":67,"contacts":68},"PICU Ospedale Mayer","Florence",{"type":38,"coordinates":64},[65,66],11.24626,43.77925,{"lat":66,"lon":65},[69,71],{"name":70,"role":27,"phone":10,"phoneExt":10,"email":10},"francesca melosi",{"name":72,"role":48,"phone":10,"phoneExt":10,"email":10},"denise colosimo",{"facility":74,"status":33,"city":75,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":76,"geoPoint":80,"contacts":81},"PICU Ospedale Gaslini","Genova",{"type":38,"coordinates":77},[78,79],11.87211,45.21604,{"lat":79,"lon":78},[82,84],{"name":83,"role":27,"phone":10,"phoneExt":10,"email":10},"stefano pezzato",{"name":85,"role":48,"phone":10,"phoneExt":10,"email":10},"marta fedriga",{"facility":87,"status":88,"city":89,"state":10,"zip":90,"country":35,"countryCode":36,"cosmosGeoPoint":91,"geoPoint":95,"contacts":96},"PICU University Hospital Padova","RECRUITING","Padova","35128",{"type":38,"coordinates":92},[93,94],11.14261,44.38225,{"lat":94,"lon":93},[97,99,101],{"name":98,"role":27,"phone":10,"phoneExt":10,"email":29},"angela amigoni",{"name":100,"role":48,"phone":10,"phoneExt":10,"email":10},"elisa poletto",{"name":102,"role":48,"phone":10,"phoneExt":10,"email":10},"valentina stritoni",{"facility":104,"status":33,"city":105,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":106,"geoPoint":110,"contacts":111},"PICU Università Cattolica","Roma",{"type":38,"coordinates":107},[108,109],11.10642,44.99364,{"lat":109,"lon":108},[112],{"name":113,"role":27,"phone":10,"phoneExt":10,"email":10},"aldo mancino",{"type":24,"investigatorFullName":98,"investigatorTitle":115,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Medical Doctor","100465387","non-invasive-measurement-with-trans-cranial-doppler-versus-invasive-measurement-in-pediatric-age-100465387",false,"NCT05340062","Non Invasive Measurement With Trans Cranial Doppler Versus Invasive Measurement in Pediatric Age","The Accuracy of Intracranial Pressure Non Invasive Measurement With Trans Cranial Doppler Versus Invasive Measurement in Pediatric Age","nICPped","Inclusion Criteria:\n\n* invasive ICP placement\n\nExclusion Criteria:\n\n* cranial base fracture\n* absent informed consent","ALL","18 Years",{"count":127,"type":128},46,"ESTIMATED","OBSERVATIONAL","An increase of intracranial pressure (ICP) is an important cause of secondary brain damage. The gold standard for measuring ICP is represented by invasive positioning of intracranial ICP devices.\n\nThe most used non-invasive methods (nICP) are obtained through bed-side ultrasound, routinely used in the management of children in Pediatric Intensive Care: arterial Trancranial Doppler (TCD) and ultrasound measurement of the diameter of the optic nerve sheath (ONSD ).\n\nIn this study it is proposed to compare the measurement of nICP obtained by TCD and ONSD versus the measurement obtained by the invasive monitoring (iICP) already present.",[132],"Intracranial Hypertension",[134,135,136],"intracranial hypertension","children","cerebral perfusion","2025-01-27",{"date":139,"type":140},"2025-01-28","ACTUAL",{"date":142,"type":140},"2022-07-01",{"date":144,"type":128},"2025-12-31",{"name":5,"class":6},6]