[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100505994":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":33,"locations":42,"responsibleParty":58,"collaborators":61,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":70,"acronym":71,"eligibilityCriteria":72,"healthyVolunteers":68,"sex":73,"minAge":74,"maxAge":75,"enrollmentInfo":76,"targetDuration":10,"studyType":79,"phases":10,"briefSummary":80,"conditions":81,"keywords":10,"overallStatus":44,"whyStopped":10,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Oslo University Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group 1 - Implantation",null,"Patients admitted for CRT implantation according to current ESC\u002FAHA guidelines",[13],"Device: Cardiac Resynchronization Therapy (CRT)",{"label":15,"type":10,"description":16,"interventionNames":17},"Group 2 - 6 months control","Patients admitted for 6 months routine checkups of their CRT devices",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"DEVICE","Cardiac Resynchronization Therapy (CRT)","Cardiac resynchronization therapy (CRT) is a modality of cardiac pacing used in patients with left ventricular (LV) systolic dysfunction and dyssynchronous ventricular activation that provides simultaneous or nearly simultaneous electrical activation of the LV and right ventricle (RV) via stimulation of the LV and RV (biventricular pacing) or LV alone.",[9,15],[25,28,31],{"name":26,"affiliation":5,"role":27},"Espen W. Remme, Dr.ing","STUDY_DIRECTOR",{"name":29,"affiliation":5,"role":30},"Marit Witso, MD","PRINCIPAL_INVESTIGATOR",{"name":32,"affiliation":5,"role":30},"Hongxing Luo, MD, PhD",[34,38],{"name":26,"role":35,"phone":36,"phoneExt":10,"email":37},"CONTACT","004723071413","espen.remme@medisin.uio.no",{"name":39,"role":35,"phone":40,"phoneExt":10,"email":41},"Marit Witsø, MD","004723071402","mhwitso@medisin.uio.no",[43],{"facility":5,"status":44,"city":45,"state":10,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"RECRUITING","Oslo","0372","Norway","NO",{"type":50,"coordinates":51},"Point",[52,53],10.74609,59.91273,{"lat":53,"lon":52},[56,57],{"name":26,"role":35,"phone":36,"phoneExt":10,"email":37},{"name":39,"role":35,"phone":40,"phoneExt":10,"email":41},{"type":30,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Espen Remme","Dr.ing",[62,64],{"name":63,"class":6},"South-Eastern Norway Regional Health Authority",{"name":65,"class":6},"Norwegian Health Association","100505994","non-invasive-method-for-evaluation-of-cardiac-resynchronization-therapy-100505994",false,"NCT05868616","Non-Invasive Method for Evaluation of Cardiac Resynchronization Therapy","NIME-CRT","Inclusion Criteria:\n\n* Patients referred for CRT implantation or postoperative control at Oslo University Hospital based on the European Society of Cardiology (ESC) guidelines (2021), and criteria below:\n\n  1. Sinus rhythm.\n  2. New York Heart Association class II \u002F III heart failure on diagnosis and on optimal medical therapy.\n  3. Left bundle branch block.\n  4. QRS duration ≥ 130 ms.\n  5. Left ventricular ejection fraction ≤ 40%.\n  6. Patients must have echocardiography examination before implantation\n  7. Informed consent obtained from the patient.\n\nExclusion Criteria:\n\n1. Age \\\u003C 18 years and \\> 80 years;\n2. Ongoing atrial fibrillation;\n3. Complete atrioventricular block","ALL","18 Years","80 Years",{"count":77,"type":78},80,"ESTIMATED","OBSERVATIONAL","Left bundle branch block (LBBB) exists in about 25% of patients with congestive heart failure and is associated with worsened prognosis. Cardiac resynchronization therapy (CRT) has been one of the most important advancements in the past two decades for patients with LBBB heart failure. However, 30-40% of patients receiving a CRT do not benefit from it. In this study, the investigators will test a noninvasive device to evaluate acute effect of CRT during implantation and at follow-up CRT controls. In addition, echocardiography will be performed during CRT turned ON and OFF to visualize the changes in intraventricular flow and functional parameters of the heart.",[82,83,84,85,86],"Heart Failure","Pacemaker DDD","Cardiomyopathies","Heart Diseases","Cardiovascular Diseases","2025-08-05",{"date":89,"type":90},"2025-08-06","ACTUAL",{"date":92,"type":90},"2023-03-21",{"date":94,"type":78},"2031-03",{"name":5,"class":6},1]