[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100619662":3},{"organization":4,"armGroups":7,"interventions":34,"overallOfficials":10,"centralContacts":10,"locations":10,"responsibleParty":44,"collaborators":48,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":10,"eligibilityCriteria":58,"healthyVolunteers":59,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":10,"studyType":66,"phases":10,"briefSummary":67,"conditions":68,"keywords":70,"overallStatus":74,"whyStopped":10,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":10},{"fullName":5,"class":6},"University Hospital Erlangen","OTHER",[8,15,19,23,27,31],{"label":9,"type":10,"description":11,"interventionNames":12},"PAD - peripheral artery disease",null,"Patients with PAD",[13,14],"Diagnostic Test: MSOT - Multispectral optoacustic tomography","Diagnostic Test: CPET",{"label":16,"type":10,"description":17,"interventionNames":18},"Triathletes","very fit subjects, who do triathlon",[13,14],{"label":20,"type":10,"description":21,"interventionNames":22},"Strength athletes","Strength athletes and bodybuilders",[13,14],{"label":24,"type":10,"description":25,"interventionNames":26},"young, unathletic group","Young, healthy and unathletic subjects between 18 - 40 years",[13,14],{"label":28,"type":10,"description":29,"interventionNames":30},"older, unathletic group","older, unathletic and healthy subjects between 55 - 75 years",[13,14],{"label":32,"type":10,"description":10,"interventionNames":33},"training PAD Patients",[13,14],[35,40],{"type":36,"name":37,"description":38,"armGroupLabels":39,"otherNames":10},"DIAGNOSTIC_TEST","MSOT - Multispectral optoacustic tomography","MSOT is an advanced imaging technology that combines laser-induced ultrasound and light absorption to visualize biological tissues. By detecting ultrasound waves generated from tissue absorption of multispectral light, MSOT provides high-resolution, real-time images with functional and molecular information. One of its use is in biomedical research and clinical applications to study blood oxygenation and tissue composition, making it valuable for areas such as vascular research. In this study, we aim to utilize MSOT to differentiate between venous, arteriovenous and lymphatic malformations.",[9,20,16,28,32,24],{"type":36,"name":41,"description":42,"armGroupLabels":43,"otherNames":10},"CPET","Spiroergometry (also called cardiopulmonary exercise testing, CPET) is a diagnostic test that measures how the heart, lungs, and muscles work together during physical activity. While a person performs exercise treadmill the test records breathing gases (oxygen uptake and carbon dioxide output), ventilation, heart rate, and workload.\n\nIt provides valuable information about aerobic capacity, endurance, and limitations caused by cardiovascular, pulmonary, or metabolic conditions, making it useful in sports medicine, rehabilitation, and clinical diagnostics.",[9,20,16,28,32,24],{"type":45,"investigatorFullName":46,"investigatorTitle":47,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Ulrich Rother","Senior Consultant, Department of Vascular Surgery, University Hospital Erlangen",[49],{"name":50,"class":51},"PD Dr. med. Ferdinand Knieling, Department of pediatrics, University of Erlangen-Nürnberg","UNKNOWN","100619662","non-invasive-msot-examination-of-muscle-oxygenation-in-athletes-and-pad-patients-100619662",false,"NCT07347535","Non-invasive MSOT Examination of Muscle Oxygenation in Athletes and PAD Patients","Non-invasive Assessment of Skeletal Muscle Oxygenation in Athletes and Patients With Peripheral Arterial Disease Using Multispectral Optoacoustic Tomography During Standardized Physical Exercise","Inclusion Criteria:\n\n* Age ≥ 18 years (adults capable of giving consent)\n* Capacity to consent. The subjects are able to understand the information provided and give their written consent.\n* Belonging to one of the following cohorts:\n* Endurance athletes: at least 3× per week ≥ 60 minutes of intensive endurance training (e.g., running, cycling, swimming)\n* Strength athletes: at least 3× per week ≥ 60 minutes of intensive strength training without additional endurance training\n* Healthy control subjects: less than 2× per week \\\u003C 30 minutes of physical activity, no known vascular diseases\n* PAD patients: diagnosed peripheral arterial occlusive disease in Fontaine stage I or IIa Women of childbearing age with or without contraception may participate, as there are no risks of harm to the fetus.\n* Consent to pseudonymized data collection and storage in accordance with the GDPR.\n\nExclusion Criteria:\n\n* Age over 75 years\n* Minors (Age \\\u003C 18)\n* safety concerns on the part of the study physician, e.g., in the case of of: physical, mental or psychiatric illnesses, acute or chronic conditions that could jeopardise safety or data quality\n* Taking medications that could affect physical performance or physiological measurements (e.g., heart rate, oxygen uptake).\n* Pregnancy with known risks or complications (participation is possible in principle, but subject to individual medical review).\n* Refusal to participate or lack of informed consent.",true,"ALL","18 Years","75 Years",{"count":64,"type":65},60,"ESTIMATED","OBSERVATIONAL","The aim of the study is to present the quantitative differences in oxygenated hemoglobin in different cohorts.\n\nThis clinical study evaluates whether there is a correlation between measurements using multispectral optoacoustic tomography and the results of spiroergometry in the context of performance diagnostics.",[69],"PAD - Peripheral Arterial Disease",[71,72,73],"MSOT","PAD","Spiroergometry","NOT_YET_RECRUITING","2026-01-14",{"date":77,"type":78},"2026-01-16","ACTUAL",{"date":80,"type":65},"2026-01-01",{"date":82,"type":65},"2026-08-01",{"name":5,"class":6}]