[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100628659":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":8,"locations":7,"responsibleParty":14,"collaborators":7,"id":18,"slug":19,"hasResults":20,"nctId":21,"briefTitle":22,"officialTitle":23,"acronym":7,"eligibilityCriteria":24,"healthyVolunteers":20,"sex":25,"minAge":7,"maxAge":26,"enrollmentInfo":27,"targetDuration":7,"studyType":30,"phases":7,"briefSummary":31,"conditions":32,"keywords":7,"overallStatus":35,"whyStopped":7,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":7},{"fullName":5,"class":6},"Assiut University","OTHER",null,[9],{"name":10,"role":11,"phone":12,"phoneExt":7,"email":13},"Mennat-Allah H Abdelraheem, MD","CONTACT","+201061811080","menna128hesham1712@gmail.com",{"type":15,"investigatorFullName":16,"investigatorTitle":17,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Mennat-Allah Hesham Abdelraheem","Assistant Lecturer of Pediatrics","100628659","non-invasive-predictors-of-esophageal-varices-and-their-correlation-to-upper-endoscopic-findings-100628659",false,"NCT07464522","Non-invasive Predictors of Esophageal Varices and Their Correlation to Upper Endoscopic Findings","Non-invasive Predictors of Esophageal Varices in Pediatric Portal Hypertension and Their Correlation to Upper Endoscopic Findings","Inclusion Criteria:\n\n* Patients aged less than 18 years diagnosed with portal hypertension either due to hepatic or extrahepatic causes\n\nExclusion Criteria:\n\n* Active variceal bleeding at presentation (hemodynamic instability affects platelet\u002Fspleen parameters).\n* Previous history of variceal bleeding or endoscopic intervention (band ligation\u002Fsclerotherapy).\n* Prior surgical portosystemic shunts or Transjugular Intrahepatic Portosystemic Shunt (TIPS).\n* Current use of vasoactive drugs for primary prophylaxis (e.g., Non-selective beta-blockers).\n* Systemic infections or hematological disorders causing independent thrombocytopenia or splenomegaly (to avoid confounding the platelet\u002Fspleen ratio).","ALL","18 Years",{"count":28,"type":29},51,"ESTIMATED","OBSERVATIONAL","The goal of this observational study:\n\n* To evaluate the diagnostic accuracy of non-invasive markers in predicting the presence and grading of esophageal varices in children with portal hypertension.\n* To correlate these non-invasive markers with the severity of portal hypertension and the grade of esophageal varices to identify patients at high risk of bleeding.\n* To propose a defined protocol for screening esophageal varices in those children.",[33,34],"Esophageal Varices","Portal Hypertension","NOT_YET_RECRUITING","2026-03-19",{"date":38,"type":39},"2026-03-23","ACTUAL",{"date":41,"type":29},"2026-03-20",{"date":43,"type":29},"2028-05-20",{"name":5,"class":6}]