[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100645095":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":7,"centralContacts":16,"locations":7,"responsibleParty":22,"collaborators":7,"id":26,"slug":27,"hasResults":28,"nctId":29,"briefTitle":30,"officialTitle":31,"acronym":32,"eligibilityCriteria":33,"healthyVolunteers":28,"sex":34,"minAge":35,"maxAge":7,"enrollmentInfo":36,"targetDuration":7,"studyType":39,"phases":7,"briefSummary":40,"conditions":41,"keywords":44,"overallStatus":48,"whyStopped":7,"lastUpdateSubmitDate":49,"lastUpdatePostDateStruct":50,"startDateStruct":53,"completionDateStruct":55,"leadSponsor":57,"locationsCount":7},{"fullName":5,"class":6},"King Chulalongkorn Memorial Hospital","OTHER",null,[9,13],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":7},"DEVICE","High Flow Oxygen","If HFNC is used as the first device, the settings will be determined at the discretion of the clinical team.\n\n-If HFNC is used as the second device, the oxygen concentration (FiO₂) will be set equivalent to that of the nasal prong (using estimated FiO2 = current FiO2 + 0.03 \\*O2 flow rate (L\u002Fmin))(27), with a flow rate of 50 L\u002Fmin. This is based on a 6-month SICU observation showing that nearly all patients after ventilator weaning were initially set on HFNC at 50 L\u002Fmin and subsequently weaned down with FiO2 30-40%. This approach allows the HFNC settings to be as consistent as possible with routine attending physician practice and ensures that patients in this study receive HFNC settings that are as uniform as possible, without interfering with the primary treatment plan.",{"type":10,"name":14,"description":15,"armGroupLabels":7,"otherNames":7},"Nasal canula oxygen","if nasal prong is used as the first device, the setting will be determined at the discretion of the clinical team.\n\nIf nasal prong is used as the second device, the FiO₂ will be set with a flow rate of 5 LPM (will be equivalent 40% of FiO2)",[17],{"name":18,"role":19,"phone":20,"phoneExt":7,"email":21},"Papawee Chennavasin, MD","CONTACT","+667843160","papawee.c@gmail.com",{"type":23,"investigatorFullName":24,"investigatorTitle":25,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"SPONSOR_INVESTIGATOR","Papawee Chennavasin","Miss","100645095","non-invasive-respiratory-monitoring-to-predict-successful-separation-from-mechanical-ventilation-following-upper-abdominal-surgery-100645095",false,"NCT07678502","Non-Invasive Respiratory Monitoring to Predict Successful Separation From Mechanical Ventilation Following Upper Abdominal Surgery","NON-INVASIVE RESPIRATORY MONITORING TO PREDICT A SEPARATION FROM MECHANICAL VENTILATION IN PATIENTS WITH UPPER ABDOMINAL SURGERY: THE VALUE STUDY - PREVALENCE, PREDICTIVE AND PRAGMATICAL STUDY","VALUE","Inclusion criteria\n\n* Age of ≥ 18 years\n* Post elective open upper abdominal surgery with mechanical ventilation\n* Get readiness for mechanical ventilation weaning with pressure support 5-8 cmH2O and PEEP 5-8 cmH2O set by clinical team and prompt extubation assessed by clinical team\n\nExclusion criteria\n\n* Previous tracheostomy\n* Contraindication to EIT placement: pacemaker\u002Fdefibrillator implantation, burns at the area of EIT placement\n* Patient with end-of-life plan\n* Emergency operation","ALL","18 Years",{"count":37,"type":38},40,"ESTIMATED","OBSERVATIONAL","The VALUE Study is a two-phase, prospective clinical trial conducted at King Chulalongkorn Memorial Hospital (KCMH). The study evaluates the prevalence of mechanical ventilation (MV) separation failure in post-open upper abdominal surgery patients and investigates whether non-invasive bedside respiratory monitoring tools can rapidly predict extubation failure.\n\nThe protocol focuses on Electrical Impedance Tomography (EIT) metrics-specifically regional ventilation distribution and the absolute ventral-to-dorsal difference-alongside ventilator-derived measures of respiratory drive. It also tracks physiological responses and clinical outcomes, including dyspnea using the Intensive Care Respiratory Distress Observation Scale (IC-RDOS) and the ROX index, across standard post-extubation oxygen delivery methods (nasal cannula vs. High-Flow Nasal Cannula \\[HFNC\\]).",[42,43],"Upper Abdominal Surgery","Critical Ill Patients in SICU",[45,46,47],"pulmonary complication","postoperative care","upper abdominal surgery","NOT_YET_RECRUITING","2026-06-28",{"date":51,"type":52},"2026-07-01","ACTUAL",{"date":54,"type":38},"2026-07",{"date":56,"type":38},"2027-12",{"name":24,"class":6}]