[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100524950":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":47,"centralContacts":56,"locations":66,"responsibleParty":79,"collaborators":61,"id":83,"slug":84,"hasResults":85,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":61,"eligibilityCriteria":89,"healthyVolunteers":85,"sex":90,"minAge":91,"maxAge":92,"enrollmentInfo":93,"targetDuration":61,"studyType":96,"phases":97,"briefSummary":99,"conditions":100,"keywords":103,"overallStatus":69,"whyStopped":61,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":115},{"fullName":5,"class":6},"Mansoura University","OTHER",[8,15,19,22],{"label":9,"type":10,"description":11,"interventionNames":12},"(Group 1) 25 (H. NIV): Hypoxemic patients{hypoxemic NIV group}","ACTIVE_COMPARATOR","who will undergo fiber-optic bronchoscopy under non- invasive ventilation and conventional oxygen therapy",[13,14],"Device: non- invasive ventilator","Device: fiber-optic bronchoscopy",{"label":16,"type":10,"description":17,"interventionNames":18},"(Group 2) 25 (H. conv.): Hypoxemic patients{hypoxemic conventional group }","who will undergo conventional fiber-optic bronchoscopy under conventional oxygen therapy without non- invasive ventilation",[14],{"label":20,"type":10,"description":11,"interventionNames":21},"(Group 3) 25 (N.H.NIV): Non- hypoxemic patients{non-hypoxemic NIV group}",[13,14],{"label":23,"type":10,"description":17,"interventionNames":24},"(Group 4) 25(N.H. conv.): Non- hypoxemic patients{non-hypoxemic conventional group}",[14],[26,34,39,43],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"DEVICE","non- invasive ventilator","Group 1 (hypoexemic patient who will undergo bronchoscopy under non- invasive ventilation{NIV} and conventional o2 therapy) will be on NIV half an hour prior and throughout the bronchoscopic sampling and after the procedure until reach the baseline criteria",[9,20],[32,33],"fiber-optic bronchoscopy","conventional oxygen therapy",{"type":27,"name":32,"description":35,"armGroupLabels":36,"otherNames":37},"Group 2 (hypoxemic patients who will undergo conventional bronchoscopy under conventional o2 therapy without NIV ) will be on conventional oxygen therapy half an hour prior and throughout the bronchoscopic sampling and after the procedure until reach the baseline criteria",[9,16,20,23],[38,33],"conventional bronchoscopy under oxygen therapy",{"type":27,"name":28,"description":40,"armGroupLabels":41,"otherNames":42},"Group 3 (non- hypoxemic patients who will undergo bronchoscopy under non- invasive ventilation{NIV} and conventional o2 therapy) will be on NIV throughout the bronchoscopic sampling and after the procedure until reach the baseline criteria",[9,20],[32,33],{"type":27,"name":32,"description":44,"armGroupLabels":45,"otherNames":46},"Group 4 (non- hypoxemic patients who will undergo conventional bronchoscopy without non- invasive ventilation{NIV) will be on conventional oxygen therapy throughout the bronchoscopic sampling and after the procedure until reach the baseline criteria",[9,16,20,23],[38,33],[48,51,54],{"name":49,"affiliation":5,"role":50},"Ahmed El sayed, MD","STUDY_CHAIR",{"name":52,"affiliation":5,"role":53},"Amr Moawad, MD","STUDY_DIRECTOR",{"name":55,"affiliation":5,"role":53},"Mohamed Mansour, MD",[57,63],{"name":58,"role":59,"phone":60,"phoneExt":61,"email":62},"Walaa Abd El Aziz, MD","CONTACT","01064904172",null,"Wm22446699@gmail.com",{"name":55,"role":59,"phone":64,"phoneExt":61,"email":65},"01009400754","Mohammedmansour.md@gmail.com",[67],{"facility":68,"status":69,"city":70,"state":61,"zip":61,"country":71,"countryCode":72,"cosmosGeoPoint":73,"geoPoint":78,"contacts":61},"Walaa Maher Abd ElAziz,","RECRUITING","Al Mansurah","Egypt","EG",{"type":74,"coordinates":75},"Point",[76,77],31.38069,31.03637,{"lat":77,"lon":76},{"type":80,"investigatorFullName":81,"investigatorTitle":82,"investigatorAffiliation":5,"oldNameTitle":61,"oldOrganization":61},"PRINCIPAL_INVESTIGATOR","Walaa Maher Abd El aziz","Principal Investigator Walaa Maher abd El aziz, Head of NIV Ahmed Younis El-sayed, Clinical Professor Amr Abd El-Hamid Moawad and Director Mohamed Ahmed Mansour Affiliation: Mansoura University","100524950","non-invasive-ventilation-assisted-fiber-optic-bronchoscopy-100524950",false,"NCT06115395","Non-invasive Ventilation Assisted Fiber-optic Bronchoscopy","Efficacy and Safety of Using Non-invasive Ventilation Assisted Fiber-optic Bronchoscopy","Inclusion Criteria:\n\n* Patients who admitted to the pulmonology ward or intensive care unit with any (diagnostic and\u002For therapeutic) bronchoscopy indication.\n\n  1. Age 18 years or more.\n  2. Patients accepted to participate in the study.\n\nExclusion Criteria:\n\n* Patients with:\n\n  1. Cardiac or respiratory arrest.\n  2. Impaired consciousness or confusion.\n  3. Type II respiratory failure.\n  4. Hemodynamic instability.\n  5. Inability to cooperate or to protect the airway.\n  6. Vomiting, bowel obstruction, recent upper gastrointestinal tract surgery and esophageal injury.\n  7. Patients refusing participation in the study.\n  8. Patients unfit for NIV and or NIV mask.\n  9. Intubation and or invasive ventilation candidates.\n  10. Presence of contraindications for bronchoscopy procedure such as insufficient platelet number or coagulopathy.","ALL","18 Years","70 Years",{"count":94,"type":95},100,"ESTIMATED","INTERVENTIONAL",[98],"NA","The purpose of this study is the evaluation of using bi-level positive airway pressure ventilation in candidates for fiber-optic bronchoscopy regarding benefits and drawbacks.",[101,102],"Lung","Diseases",[104,105],"non- invasive ventilation","fiber-optic bronchoscopy.","2025-05-07",{"date":108,"type":109},"2025-05-11","ACTUAL",{"date":111,"type":109},"2020-07-25",{"date":113,"type":95},"2025-12-31",{"name":5,"class":6},1]