[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100624681":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":35,"centralContacts":43,"locations":50,"responsibleParty":69,"collaborators":30,"id":72,"slug":73,"hasResults":74,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":30,"eligibilityCriteria":78,"healthyVolunteers":79,"sex":80,"minAge":81,"maxAge":82,"enrollmentInfo":83,"targetDuration":30,"studyType":86,"phases":87,"briefSummary":89,"conditions":90,"keywords":93,"overallStatus":101,"whyStopped":30,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":111},{"fullName":5,"class":6},"Ondokuz Mayıs University","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Stable angina and periodontitis group (SAP group)","EXPERIMENTAL","Individuals diagnosed with stable angina and periodontitis who will receive non-surgical",[13],"Procedure: Non-surgical periodontal therapy (scaling and root planing)",{"label":15,"type":10,"description":16,"interventionNames":17},"Periodontitis group (P group)","Cardiovascularly healthy individuals diagnosed with periodontitis who will receive non-surgical periodontal therapy, including scaling and root planing.",[13],{"label":19,"type":20,"description":21,"interventionNames":22},"Control group (C group)","ACTIVE_COMPARATOR","Periodontally and cardiovascularly healthy individuals who will receive routine professional dental cleaning and standardized oral hygiene instruction.",[23],"Procedure: Non-surgical periodontal therapy (Professional dental cleaning)",[25,31],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"PROCEDURE","Non-surgical periodontal therapy (scaling and root planing)","Non-surgical periodontal therapy will include full-mouth scaling and root planing performed using hand instruments and\u002For ultrasonic devices to remove supra- and subgingival plaque and calculus.",[15,9],null,{"type":26,"name":32,"description":33,"armGroupLabels":34,"otherNames":30},"Non-surgical periodontal therapy (Professional dental cleaning)","Supragingival calculus and plaque removal with standardized oral hygiene instruction.",[19],[36,40],{"name":37,"affiliation":38,"role":39},"Sena Altintas, DDS","Ondokuz Mayis University Department of Periodontology","PRINCIPAL_INVESTIGATOR",{"name":41,"affiliation":38,"role":42},"Feyza Otan Ozden, Professor","STUDY_DIRECTOR",[44,48],{"name":37,"role":45,"phone":46,"phoneExt":30,"email":47},"CONTACT","+905540270097","senaltintas144@gmail.com",{"name":41,"role":45,"phone":30,"phoneExt":30,"email":49},"feyza_otan@yahoo.com",[51],{"facility":52,"status":30,"city":53,"state":54,"zip":55,"country":56,"countryCode":30,"cosmosGeoPoint":57,"geoPoint":62,"contacts":63},"Ondokuz Mayis University","Samsun","Atakum","55270","Turkey (Türkiye)",{"type":58,"coordinates":59},"Point",[60,61],36.3361,41.27976,{"lat":61,"lon":60},[64,68],{"name":65,"role":45,"phone":66,"phoneExt":30,"email":67},"Ondokuz Mayis University Faculty of Dentistry","+90362 312 19 19 \u002F 8121","disinfo@omu.edu.tr",{"name":37,"role":39,"phone":30,"phoneExt":30,"email":30},{"type":39,"investigatorFullName":70,"investigatorTitle":71,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"Sena Altintas","Research assistant","100624681","non-surgical-periodontal-therapy-and-cardiac-biomarkers-in-stable-angina-100624681",false,"NCT07412795","Non-Surgical Periodontal Therapy and Cardiac Biomarkers in Stable Angina","Effect of Non-Surgical Periodontal Therapy on Ischemia-Modified Albumin and Soluble ST2 in Patients With Stable Angina","Inclusion Criteria:\n\n* Willingness to participate in the study and provide written informed consent\n* Age 18 years or older\n* No periodontal treatment within the past 6 months\n* No use of local or systemic antibiotics within the past 3 months\n\nExclusion Criteria:\n\n* Unwillingness to participate in the study or to provide informed consent\n* Age under 18 years\n* Use of local or systemic antibiotics for the treatment of widespread infection\n* within the past 3 months\n* Receipt of periodontal treatment within the past 6 months\n* Pregnancy or lactation (for female participants)\n* History of acute myocardial infarction within the past 6 months",true,"ALL","18 Years","65 Years",{"count":84,"type":85},60,"ESTIMATED","INTERVENTIONAL",[88],"NA","The goal of this clinical study is to learn whether gum treatment can improve heart health. Researchers will compare blood markers related to heart disease before and after routine gum treatment.\n\nThe main questions this study aims to answer are:\n\nIs gum disease a risk factor for heart disease? Can treating gum disease lower the risk of heart disease? Adults with stable angina (a type of heart disease) and adults without heart disease may take part in this study.\n\nAll participants will receive routine, non-surgical gum treatment, which is a standard dental care procedure. This includes professional cleaning to remove plaque and tartar from the teeth and practical education on tooth brushing and cleaning between the teeth. The treatment will be performed by a single researcher and completed in one visit within about one hour.\n\nParticipants will:\n\nProvide a blood sample before gum treatment Receive routine, non-surgical gum treatment Return after three months for a follow-up visit Provide a second blood sample This study does not involve experimental drugs or devices. Participation is voluntary, and there is no cost to participants. The results may help researchers better understand how gum health is related to heart health.",[91,92],"Stable Angina","Periodontitis",[94,95,96,97,98,99,100],"Non-surgical Periodontal Treatment","Cardiovascular Disease","Cardiovascular Biomarkers","stable angina","soluble ST2","periodontitis","IMA","NOT_YET_RECRUITING","2026-02-13",{"date":104,"type":105},"2026-02-17","ACTUAL",{"date":107,"type":85},"2026-02-20",{"date":109,"type":85},"2026-08-05",{"name":5,"class":6},1]