[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100542523":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":19,"locations":24,"responsibleParty":56,"collaborators":10,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":63,"acronym":10,"eligibilityCriteria":64,"healthyVolunteers":65,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":10,"studyType":72,"phases":10,"briefSummary":73,"conditions":74,"keywords":77,"overallStatus":26,"whyStopped":10,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Turku University Hospital","OTHER_GOV",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Type 1 diabetes",null,"Pregnant woman with type 1 diabetes.",{"label":13,"type":10,"description":14,"interventionNames":10},"Healthy controls","Pregnant women with uncomplicated pregnancy and normal oral glucose tolerance test (OGTT).",[16],{"name":17,"affiliation":5,"role":18},"Mikael Huhtala, M.D., Ph.D.","PRINCIPAL_INVESTIGATOR",[20],{"name":17,"role":21,"phone":22,"phoneExt":10,"email":23},"CONTACT","+35823130000","misahu@utu.fi",[25,38],{"facility":5,"status":26,"city":27,"state":10,"zip":10,"country":28,"countryCode":29,"cosmosGeoPoint":30,"geoPoint":35,"contacts":36},"RECRUITING","Turku","Finland","FI",{"type":31,"coordinates":32},"Point",[33,34],22.26869,60.45148,{"lat":34,"lon":33},[37],{"name":17,"role":21,"phone":10,"phoneExt":10,"email":23},{"facility":5,"status":26,"city":27,"state":10,"zip":10,"country":28,"countryCode":29,"cosmosGeoPoint":39,"geoPoint":41,"contacts":42},{"type":31,"coordinates":40},[33,34],{"lat":34,"lon":33},[43,45,47,50,52,54],{"name":44,"role":21,"phone":10,"phoneExt":10,"email":10},"Mikael Huhtala, MD, PhD",{"name":46,"role":18,"phone":10,"phoneExt":10,"email":10},"Mikae Huhtala, MD, PhD",{"name":48,"role":49,"phone":10,"phoneExt":10,"email":10},"Eeva Ekholm, MD, Adj. Prof.","SUB_INVESTIGATOR",{"name":51,"role":49,"phone":10,"phoneExt":10,"email":10},"Kaarin Mäkikallio, MD, Prof.",{"name":53,"role":49,"phone":10,"phoneExt":10,"email":10},"Kalle Korhonen, MD, PhD",{"name":55,"role":49,"phone":10,"phoneExt":10,"email":10},"Kristiina Tertti, MD, Adj. Prof.",{"type":18,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Mikael Huhtala","Physician, MD, PhD","100542523","noninvasive-evaluation-of-fetal-hyperinsulinemia-with-ultrasound-radiomics-100542523",false,"NCT06343974","Noninvasive Evaluation of Fetal Hyperinsulinemia With Ultrasound Radiomics","Inclusion Criteria:\n\n* Age between 18-45 years\n* Capable to give an informed consent\n* Singleton pregnancy\n* Planning to deliver in Turku University Hospital\n* Maternal BMI \\\u003C 40\n* Gestational age should be confirmed by first trimester ultrasound\n* Normal oral glucose tolerance test (OGTT) at 24-28 gestational weeks in controls\n\nExclusion Criteria:\n\n* Major fetal chromosomal, genetic, or structural anomaly\n* Fetal growth restriction, or birth weight \\\u003C 10th centile\n* Birth weight \\> 90th centile or polyhydramnios in the controls\n* Non-reassuring fetal status requiring immediate treatment, or intrauterine fetal demise\n* Verified fetal infection (e.g. cytomegalovirus, toxoplasma, hepatitis B and C), excluding bacterial infection due to intrapartum chorioamnionitis\n* Placenta accreta spectrum disorder\n* Major maternal medical condition requiring systemic pharmacological treatment, other than non-severe hypertension, hypothyroidism, asthma, mild psychiatric disorders, etc.\n* Alcohol or tobacco use, or substance abuse in pregnancy",true,"FEMALE","18 Years","45 Years",{"count":70,"type":71},60,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to compare fetal liver ultrasound radiomics between pregnancies complicated by type 1 diabetes and healthy controls.\n\nThe main questions it aims to answer are:\n\n* Are fetal liver ultrasound radiomic features reproducible?\n* Does fetal liver ultrasound radiomics differ between pregnancies complicated by type 1 diabetes and healthy controls?\n\nParticipants will undergo ultrasound examination to collect ultrasound data for the analyses.",[75,76],"Pregnancy in Diabetic","Diabetes Mellitus, Type 1",[78,79,80,81,82,83],"ultrasonography","fetus","radiomics","hyperinsulinemia","liver","pregnancy","2025-11-23",{"date":86,"type":87},"2025-11-28","ACTUAL",{"date":89,"type":87},"2024-10-11",{"date":91,"type":71},"2026-06-01",{"name":5,"class":6},2]