[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100595040":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":15,"locations":21,"responsibleParty":38,"collaborators":10,"id":41,"slug":42,"hasResults":43,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":10,"eligibilityCriteria":47,"healthyVolunteers":43,"sex":48,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":10,"studyType":54,"phases":10,"briefSummary":55,"conditions":56,"keywords":10,"overallStatus":24,"whyStopped":10,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":67},{"fullName":5,"class":6},"First Affiliated Hospital of Chongqing Medical University","OTHER",[8,11,13],{"label":9,"type":10,"description":10,"interventionNames":10},"Training set",null,{"label":12,"type":10,"description":10,"interventionNames":10},"Test set",{"label":14,"type":10,"description":10,"interventionNames":10},"Pathological set",[16],{"name":17,"role":18,"phone":19,"phoneExt":10,"email":20},"xinwei Chen","CONTACT","+8615178870590","cxw9977@163.com",[22],{"facility":23,"status":24,"city":25,"state":10,"zip":10,"country":26,"countryCode":27,"cosmosGeoPoint":28,"geoPoint":33,"contacts":34},"The First Affiliated Hospital of Chongqing Medical University","RECRUITING","Chongqing","China","CN",{"type":29,"coordinates":30},"Point",[31,32],106.55771,29.56026,{"lat":32,"lon":31},[35],{"name":36,"role":18,"phone":37,"phoneExt":10,"email":20},"xinwei chen","15178870590",{"type":39,"investigatorFullName":17,"investigatorTitle":40,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","PHD","100595040","noninvasive-intratumor-heterogeneity-evaluation-in-hnscc-100595040",false,"NCT07027280","Noninvasive Intratumor Heterogeneity Evaluation in HNSCC","Noninvasive Intratumor Heterogeneity Evaluation in HNSCC With Multi-omics Insights and Therapeutic Targets","Inclusion Criteria:\n\nPathologically confirmed head and neck squamous cell carcinoma (HNSCC). Complete clinical, imaging, and pathological data. Available complete follow-up information.\n\nExclusion Criteria:\n\nPatients who received chemotherapy or radiotherapy before surgery. Poor image quality. Tumors too small to be easily identified. History of other concurrent malignant tumors.","ALL","15 Years","89 Years",{"count":52,"type":53},700,"ESTIMATED","OBSERVATIONAL","This study focuses on tumor heterogeneity, a core challenge in the field of oncology, and innovatively utilizes patient imaging data to deeply mine and analyze intratumoral heterogeneity. By constructing an imaging analysis model for tumor heterogeneity and associating this model with clinical, pathological, transcriptomic, and metabolomic data of patients, a multi-omics decoding of tumor heterogeneity is achieved. The main questions it aims to address are:\n\nCan the ITH model stratify patients' treatment efficacy and prognosis assessment? Can pathological and multi-omics sequencing map the mechanisms behind the ITH model?",[57],"Head and Neck Cancer","2025-06-16",{"date":60,"type":61},"2025-06-18","ACTUAL",{"date":63,"type":61},"2025-02-27",{"date":65,"type":53},"2025-08-15",{"name":5,"class":6},1]