[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100582031":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":40,"responsibleParty":57,"collaborators":18,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":65,"eligibilityCriteria":66,"healthyVolunteers":61,"sex":67,"minAge":68,"maxAge":18,"enrollmentInfo":69,"targetDuration":18,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":81,"overallStatus":43,"whyStopped":18,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Sykehuset Innlandet HF","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Mesh group","EXPERIMENTAL","The patients in the mesh group are closed with small bites technique and in addition receiving an onlay polypropylene mesh when closing the fascia in midline laparotomies. These patients receive a subcutaneous drain to prevent seroma.",[13],"Procedure: Prophylactic polypropylene onlay mesh",{"label":15,"type":16,"description":17,"interventionNames":18},"Suture group","NO_INTERVENTION","The patients in the suture group are closed with small bites technique.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"PROCEDURE","Prophylactic polypropylene onlay mesh","The patients in the mesh group are closed with small bites technique and in addition receiving an onlay polypropylene mesh when closing the fascia in midline laparotomies.",[9],[26],{"name":27,"affiliation":28,"role":29},"Lars Martin Rekkedal, MD BBA","Chief of surgery Hamar Hospital","STUDY_CHAIR",[31,36],{"name":32,"role":33,"phone":34,"phoneExt":18,"email":35},"Gjertrud H Kjostolfsen, MD","CONTACT","0047 90236405","gjertrud.hole.kjostolfsen@sykehuset-innlandet.no",{"name":37,"role":33,"phone":38,"phoneExt":18,"email":39},"Jorunn Skattum, MD PhD","0047 90236680","jorunn.skattum@sykehuset-innlandet.no",[41],{"facility":42,"status":43,"city":44,"state":18,"zip":18,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Innlandet Hospital Trust","RECRUITING","Hamar","Norway","NO",{"type":48,"coordinates":49},"Point",[50,51],11.06798,60.7945,{"lat":51,"lon":50},[54],{"name":27,"role":33,"phone":55,"phoneExt":18,"email":56},"0047 90041959","lars.martin.rekkedal@sykehuset-innlandet.no",{"type":58,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100582031","nopro---norwegian-hernia-prophylaxis-study-100582031",false,"NCT06858020","NoPro - Norwegian Hernia Prophylaxis Study","NoPro - Norwegian Hernia Prophylaxis Study: Onlay Mesh Versus Small Bite Suture Technique Closure of Midline Laparotomies","NoPro","Inclusion Criteria:\n\n* Surgery predominantly done my midline laparotomy\n* Age 18 years old or older\n* Written consent by patient\u002Ffamily\n* Midline laparotomy with delayed closure\n* No exclusion criteria\n\nExclusion Criteria:\n\n* Age under 18 years\n* Pregnancy\n* Previous abdominal midline hernia mesh repair\n* Abdominal compartment syndrome\n* Linea alba closure not possible\n* Life expectancy under six months\n* Hernia in the midline with transverse diameter lager than 2 cm","ALL","18 Years",{"count":70,"type":71},150,"ESTIMATED","INTERVENTIONAL",[74],"NA","A multicenter randomized controlled trial comparing midline laparotomy closures using the small-bite suture technique alone to those using the small-bite suture technique with an additional onlay prophylactic polypropylene mesh. The primary endpoint is the incidence of incisional hernias in both groups after one year.",[77,78,79,80],"Incisional Hernia After Midline Laparotomy","Quality of Life (QOL)","Burst Abdomen","Surgical Site Infections",[82,83,84,85],"prophylactic mesh","onlay","incisional hernia","midline laparotomy","2025-02-28",{"date":88,"type":89},"2025-03-05","ACTUAL",{"date":91,"type":89},"2025-02-17",{"date":93,"type":71},"2028-12",{"name":5,"class":6},1]