[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100500850":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":28,"locations":39,"responsibleParty":57,"collaborators":33,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":66,"eligibilityCriteria":67,"healthyVolunteers":62,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":33,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":80,"overallStatus":42,"whyStopped":33,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Region Stockholm","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Low Carb diet","OTHER","Participants will have acces to a plattform with recepies containing 30 g carbohydrate \u002F day during the first three months and thereafter recepies containing 80 g carbohydrate\u002F day during the remaining 12 months",[13],"Other: Low carb diet",{"label":15,"type":10,"description":16,"interventionNames":17},"Low Calori diet","Participants will be asked to by low caloric diet replacement containing 850 kCal\u002Fday during the first 3 months, aiming for a weight loss of 10 kg during and thereafter will have access to recepies containing less calorie for weight maintenance during the remaining 12 months",[13],[19],{"type":10,"name":20,"description":21,"armGroupLabels":22,"otherNames":23},"Low carb diet","Low calori diet",[15,9],[21],[25],{"name":26,"affiliation":5,"role":27},"Neda Rajamand Ekberg, MD, PhD","PRINCIPAL_INVESTIGATOR",[29,35],{"name":30,"role":31,"phone":32,"phoneExt":33,"email":34},"Neda Rajamand Ekberg, M.D. PhD.","CONTACT","+468-123 671 50",null,"neda.ekberg@ki.se",{"name":36,"role":31,"phone":37,"phoneExt":33,"email":38},"Katarina Fagerskiold, nurse","+468-123 671 76","katarina.fagerskiold@regionstockholm.se",[40],{"facility":41,"status":42,"city":43,"state":33,"zip":33,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Center for diabetes, Academic Specialist center","RECRUITING","Stockholm","Sweden","SE",{"type":47,"coordinates":48},"Point",[49,50],18.06871,59.32938,{"lat":50,"lon":49},[53,55],{"name":36,"role":31,"phone":54,"phoneExt":33,"email":38},"+46-8-123 671 76.",{"name":56,"role":27,"phone":33,"phoneExt":33,"email":33},"Neda Rajamand Ekberg, M.D; PhD",{"type":27,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":33,"oldOrganization":33},"Neda Ekberg","Consultant physician, associate professor","100500850","normalized-glucose-levels-in-type-2-diabetes-with-carbohydrate-or-caloric-restriction-100500850",false,"NCT05801614","Normalized Glucose Levels in Type 2 Diabetes With Carbohydrate or Caloric Restriction","Normalized Glucose Levels in Type 2 Diabetes With Carbohydrate or Caloric Restriction: a Randomized Controlled Trial (CarborCal)","CarborCal","Inclusion Criteria:\n\n* HbA1c \\> 48 mmol\u002Fmol (with or without medical treatment);\n* less than 6 years since the diagnosis of T2D\n* BMI ≥ 27 kg\u002Fm2 (≥ 25 kg\u002Fm2 for Asians).\n\nExclusion Criteria:\n\n* Insulin deficiency.\n* HbA1c concentration of 12% or more (≥108 mmol\u002Fmol),\n* treatment with sulphonyl urea or sodium-glucose-cotrasporter2-inhibitor (SGL2-i),\n* myocardial infarction within the previous 6 months,\n* severe or unstable heart failure\n* other severe diseases including cancer, psychiatric\u002Feating disorders, severe depression - substance abuse,\n* conditions that may affect the ability of patients to participate in the study","ALL","24 Years","70 Years",{"count":72,"type":73},286,"ESTIMATED","INTERVENTIONAL",[76],"NA","This is a randomized controlled trial to determine whether a low-carbohydrate (LC) diet can lead to normalized blood glucose levels in patients with short duration of type 2 diabetes (T2D). Previous studies have shown that caloric restricted diet leading to weight loss can normalize blood glucose levels in approximately 50% of patients with a short duration of diabetes type 2. However, caloric restriction is difficult to maintain. Less restrictive approaches are needed. The hypothesis in this study is that Low carbohydrate diet can results in normalized blood glucose levels in T2D and can be an alternative to caloric restriction diet, both in the shorter term (3 months) and longer term (15 months). The outcome of this study leading to reduction of HbA1c is important for prevention of diabetes complications.",[79],"Diabetes Mellitus Type 2 in Obese",[81,82,83,84],"Diabetes Mellitus Type 2","Diet","Carbohydrate-Restricted","Caloric restriction","2023-12-27",{"date":87,"type":88},"2024-01-02","ACTUAL",{"date":90,"type":88},"2022-02-28",{"date":92,"type":73},"2027-02-28",{"name":5,"class":6},1]