[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100633599":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":25,"locations":31,"responsibleParty":51,"collaborators":10,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":55,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":66,"studyType":67,"phases":10,"briefSummary":68,"conditions":69,"keywords":71,"overallStatus":33,"whyStopped":10,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Germans Trias i Pujol Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Consecutive patients with at least moderate mitral regurgitaiton",null,"Patients with at least moderate mitral regurgitation of any etiology who are referred for transesophageal echocardiographic evaluation will be included. Patients without contraindications for cardiac magnetic resonance will undergo this exam to compare the echocardiographic data with the cardiac magnetic resonance data as indicated in the study.",[13],"Device: analysis of the performance of an artificial intelligenced based software for analysis of 3D tranesophageal echocardiography data",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DEVICE","analysis of the performance of an artificial intelligenced based software for analysis of 3D tranesophageal echocardiography data","The analysis of mitral regurgitation in current practice is based on multiparametric approach of several 2-dimensional Doppler echocardiographic parameters and quantification of mitral regurgitant volume and effective regurgitant orifice area measured with the proxymal isovelocity surface area. This novel algorithm based on artificial intelligence based software may change clinical practice if demonstrates that provides more accurate estimation of the severity of mitral regurgitation.",[9],[21],{"name":22,"affiliation":23,"role":24},"Carlo F Guarino, MD","Hospital University Germans Trias i Pujol","PRINCIPAL_INVESTIGATOR",[26],{"name":27,"role":28,"phone":29,"phoneExt":10,"email":30},"Victoria Delgado, Head of Cardiovascular Imaging department, MD, PhD","CONTACT","+34 93 497 89 15","cardiologia.germanstrias@gencat.cat",[32],{"facility":23,"status":33,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"RECRUITING","Badalona","Barcelona","08916","Spain","ES",{"type":40,"coordinates":41},"Point",[42,43],2.24741,41.45004,{"lat":43,"lon":42},[46],{"name":47,"role":28,"phone":48,"phoneExt":49,"email":50},"Victoria Delgado, MD, PhD","934651200","+34 93 497 89","vdelgadog.germanstrias@gencat.cat",{"type":52,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100633599","novel-3-dimensional-echocardiographic-quantification-of-mitral-regurgitant-volume-100633599",false,"NCT07528781","Novel 3-dimensional Echocardiographic Quantification of Mitral Regurgitant Volume","AIM_3D","Inclusion Criteria:\n\n* Patients with at least moderate mitral regurgitation of any etiology\n* Patients with good transesophageal echocardiography image quality\n\nExclusion Criteria:\n\n* Patients with prior transcatheter or surgical mitral valve intervention\n* Patients with contraindications for transesophageal echocardiography or cardiac magnetic resonance","ALL","18 Years","95 Years",{"count":64,"type":65},200,"ESTIMATED","2 Years","OBSERVATIONAL","The goal of this observational study is demonstrate that a novel artificial intelligence based software for the quantification of the mitral regurgitation on 3-dimensional transesophageal echocardiography (3D CFQ) is more reproducible and accurate than the conventional assessment of mitral regurgitation performed with 2-dimensional echocardiography. The main question aims to answer is to demonstrate the agreement between 3D-CFQ measurement of the mitral regurgitant volume and the cardiac magnetic resonance measurement of the regurgitant volume is better than the agreement between 2-dimensional echocardiography and cardiac magnetic resonance. If this is demonstrated, we would like to test the accuracy of this tool to be applied in acute settings such as transcatheter interventions to decide the therapy to follow.\n\nParticipants will undergo clinically indicated transesophageal echocardiography to characterize the mechanism and severity of mitral regurgitation and to cardiac magnetic resonance to be used as reference stadard to define the mitral regurgitation severity.",[70],"Moderate or Severe Mitral Regurgitation",[72,73,74],"mitral regurgitation","mitral valve surgery","transcatheter intervention","2026-04-09",{"date":77,"type":78},"2026-04-14","ACTUAL",{"date":80,"type":65},"2026-03-17",{"date":82,"type":65},"2028-04-01",{"name":5,"class":6},1]