[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100519892":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":54,"collaborators":58,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":26,"eligibilityCriteria":70,"healthyVolunteers":66,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":26,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":26,"overallStatus":40,"whyStopped":26,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Ohio State University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Optical Correction alone","ACTIVE_COMPARATOR","Optical correction alone (16 weeks) (Each participant will complete both study conditions.)",[13],"Device: Optical Correction",{"label":15,"type":16,"description":17,"interventionNames":18},"Therapeutic (Dichoptic) Virtual Reality Games plus Continued Optical Correction","EXPERIMENTAL","Therapeutic (Dichoptic) Virtual Reality Games plus continued optical correction (16 weeks) (Each participant will complete both study conditions.)",[13,19],"Device: Therapeutic Dichoptic Virtual Reality Games",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Optical Correction","Optical correction (if needed)",[9,15],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Therapeutic Dichoptic Virtual Reality Games","Virtual Reality Game play for amblyopia treatment",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Marjean T Kulp, OD, MS","CONTACT","614-688-3336","kulp.6@osu.edu",[38],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"The Ohio State University College of Optometry","RECRUITING","Columbus","Ohio","43210","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-82.99879,39.96118,{"lat":50,"lon":49},[53],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},{"type":55,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"SPONSOR_INVESTIGATOR","Marjean Kulp","Professor",[59,62],{"name":60,"class":61},"Beta Sigma Kappa - College of Optometrists in Vision Development","UNKNOWN",{"name":63,"class":61},"VividVision","100519892","novel-amblyopia-treatment-with-virtual-reality-games-100519892",false,"NCT06049459","Novel Amblyopia Treatment With Virtual Reality Games","Novel Amblyopia Treatment With Dichoptic, Disparity-guided, Hand-Eye Coordination Enhanced, Serious, Virtual Reality Games","Inclusion Criteria:\n\nPatients ages 5 to 17 years of age\n\n* Moderate to severe unilateral amblyopia (logMAR best corrected visual acuity 0.3 to 1.3) associated with anisometropia and\u002For strabismus of ≤5pd\n* Age normal VA in the nonamblyopic eye\n* Spectacle correction (if required) worn for at least 16 weeks, or until stability of VA is demonstrated (\\\u003C0.1 logMAR change by the same testing method measured on 2 exams at least 8 weeks apart)\n* Interocular difference of ≥ 3 lines\n* No amblyopia treatment in the past 2 weeks\n* An interpupillary distance of 52-72 mm (inclusive)\n\nExclusion Criteria:\n\n* Myopia greater than -6.00 diopters (D) spherical equivalent in either eye.\n* Previous intraocular or refractive surgery.\n* Previous dichoptic treatment \\> 2 weeks in duration\n* Ocular co-morbidity that may reduce visual acuity determined by an ocular examination performed within the past 7 months (Note: nystagmus per se does not exclude the participant if the above visual acuity criteria are met).\n* Diplopia more than once per week over the last week prior to enrollment by parental report.\n* Down syndrome or cerebral palsy.\n* Light-induced seizures\n* Known simulator sickness\n* Severe developmental delay that would interfere with treatment or evaluation (in the opinion of the investigator). Participants with mild speech delay or reading and\u002For learning disabilities are not excluded.","ALL","5 Years","17 Years",{"count":75,"type":76},8,"ESTIMATED","INTERVENTIONAL",[79],"NA","The goal of this study is to compare the change in amblyopic eye acuity between treatment periods in children with amblyopia, aged 5-17 years. The main question it aims to answer is:\n\nIs a 16-week course of amblyopia treatment using Vivid Vision Therapeutic (Dichoptic) Virtual Reality Games for approx. 25 min\u002Fday, 6 days\u002Fweek more effective for improvement in amblyopic-eye VA, binocularity (stereoacuity, suppression, alignment), contrast sensitivity, attention, oculomotor function, visual-motor integration, and quality of life than 16 weeks of continued glasses alone?\n\nParticipants will each serve as their own control and complete:\n\nTreatment period 1: Continued optical correction (glasses) alone for 16 weeks; Treatment period 2: Vivid Vision Therapeutic (Dichoptic) Virtual Reality Games for 16 weeks (approx. 25min\u002Fday, 6 days\u002Fweek) plus continued optical correction",[82],"Amblyopia","2025-07-17",{"date":85,"type":86},"2025-07-22","ACTUAL",{"date":88,"type":86},"2024-03-14",{"date":90,"type":76},"2026-12-31",{"name":56,"class":6},1]