[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100597906":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":27,"centralContacts":32,"locations":37,"responsibleParty":55,"collaborators":11,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":62,"acronym":11,"eligibilityCriteria":63,"healthyVolunteers":60,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":11,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":11,"overallStatus":40,"whyStopped":11,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"West China Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"ROS-scavenging Nanoenzymes","EXPERIMENTAL",null,[13],"Drug: ROS-scavenging Nanoenzymes",{"label":15,"type":16,"description":11,"interventionNames":17},"Standard of care","ACTIVE_COMPARATOR",[18],"Behavioral: Standard of care",[20,24],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":11},"DRUG","ROS-scavenging nanoenzymes are applied to the treatment area, once daily during radiotherapy.",[9],{"type":25,"name":15,"description":15,"armGroupLabels":26,"otherNames":11},"BEHAVIORAL",[15],[28],{"name":29,"affiliation":30,"role":31},"Xingchen Peng, Prof.","Sichuan University West China Hospital","PRINCIPAL_INVESTIGATOR",[33],{"name":29,"role":34,"phone":35,"phoneExt":11,"email":36},"CONTACT","+86 18980606753","pxx2014@163.com",[38],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"West China Hospital, Sichuan University","RECRUITING","Chengdu","Sichuan","610000","China","CN",{"type":47,"coordinates":48},"Point",[49,50],104.06667,30.66667,{"lat":50,"lon":49},[53],{"name":54,"role":34,"phone":11,"phoneExt":11,"email":11},"Xingchen Peng, Phd, MD",{"type":31,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"Xingchen Peng","Professor","100597906","novel-ros-scavenging-nanoenzymes-for-the-treatment-of-radiation-dermatitis-in-patients-with-head-and-neck-cancer-100597906",false,"NCT07064577","Novel ROS-scavenging Nanoenzymes for the Treatment of Radiation Dermatitis in Patients With Head and Neck Cancer","Inclusion Criteria:\n\n1. Patients with a pathological diagnosis of non-metastatic head and neck malignant tumors;\n2. Patients deemed suitable for high-dose radiotherapy, either as a primary treatment or as postoperative treatment following surgical resection.\n\nExclusion Criteria:\n\n1. Eastern Cooperative Oncology Group performance status of \\>2;\n2. Pre-existing skin rash, ulceration or open wound in the treatment area;\n3. Inflammatory or connective tissue disorder of the skin;\n4. History of head and neck radiotherapy.","ALL","18 Years","80 Years",{"count":68,"type":69},30,"ESTIMATED","INTERVENTIONAL",[72],"NA","There is no standard treatment for radiation dermatitis. In this study, the investigators have designed novel ROS-scavenging nanoenzymes and aim to evaluate their effectiveness in preventing radiation dermatitis in patients with head and neck cancer.",[75],"Radiation Dermatitis","2025-08-03",{"date":78,"type":79},"2025-08-07","ACTUAL",{"date":81,"type":79},"2025-07-15",{"date":83,"type":69},"2025-10-15",{"name":5,"class":6},1]