[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100615168":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":13,"centralContacts":18,"locations":27,"responsibleParty":46,"collaborators":48,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":62,"eligibilityCriteria":63,"healthyVolunteers":58,"sex":64,"minAge":65,"maxAge":7,"enrollmentInfo":66,"targetDuration":7,"studyType":69,"phases":7,"briefSummary":70,"conditions":71,"keywords":74,"overallStatus":30,"whyStopped":7,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Papworth Hospital NHS Foundation Trust","OTHER_GOV",null,[9],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":7},"OTHER","Non-Interventional Study","non-interventional",[14],{"name":15,"affiliation":16,"role":17},"Andres Floto","University of Cambridge","PRINCIPAL_INVESTIGATOR",[19,24],{"name":20,"role":21,"phone":22,"phoneExt":7,"email":23},"Lucy E Gale","CONTACT","+44 1223 638000","lucy.gale1@nhs.net",{"name":25,"role":21,"phone":22,"phoneExt":7,"email":26},"Victoria Hughes, PhD","victoria.hughes1@nhs.net",[28],{"facility":29,"status":30,"city":31,"state":32,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"Royal Papworth Hospital NHS Foundation Trust","RECRUITING","Cambridge","Cambridgeshire","CB2 0AY","United Kingdom","UK",{"type":37,"coordinates":38},"Point",[39,40],0.11667,52.2,{"lat":40,"lon":39},[43,44,45],{"name":20,"role":21,"phone":22,"phoneExt":7,"email":23},{"name":25,"role":21,"phone":22,"phoneExt":7,"email":26},{"name":15,"role":17,"phone":7,"phoneExt":7,"email":7},{"type":47,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR",[49,51,52,54],{"name":50,"class":10},"LifeArc",{"name":16,"class":10},{"name":53,"class":6},"Department of Health, United Kingdom",{"name":55,"class":6},"National Institute for Health Research, United Kingdom","100615168","novel-sensors-and-artificial-intelligence-for-detection-of-acute-pulmonary-exacerbations-in-cystic-fibrosis-and-bronchiectasis-100615168",false,"NCT07289100","Novel Sensors and Artificial Intelligence for Detection of Acute Pulmonary Exacerbations in Cystic Fibrosis and Bronchiectasis","Novel Sensors and Artificial Intelligence for Detection of Acute Pulmonary Exacerbations in Cystic Fibrosis and Non-Cystic Fibrosis Bronchiectasis","NOVEL","Inclusion Criteria:\n\n* ≥ 18 years old\n* Diagnosis of CF based on genetic testing and \u002For sweat chloride levels or CT confirmed diagnosis of non-CF bronchiectasis\n* Under the care of Royal Papworth Hospital\n* Starting IV antibiotics for treatment of APE as defined by the Hill Criteria ²\n\nExclusion Criteria:\n\n* Patients unable to provide written informed consent\n* Lung transplant recipients or on lung transplant waiting list\n* Use of long-term oxygen therapy (LTOT) or non-invasive ventilation to manage respiratory failure\n* Patients unwilling to consent to their link anonymised data from home monitoring being used for research\n* Considered unsuitable for home monitoring in the opinion of the investigator\n* Patients being admitted for elective antibiotic treatment (i.e. not being admitted for acute APE treatment)","ALL","18 Years",{"count":67,"type":68},50,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to learn about new sensors that measure changes in the body that happen during a chest infection, such as breathing rate and heart rate. This study will be with adults who have either cystic fibrosis or bronchiectasis who start treatment with intravenous antibiotics (usually for around 2 weeks).\n\nThe main question it aims to answer is the change in sensor measure (such as heart rate) between the start and end of treatment for a chest infection.\n\nNo follow up visits are required for this study.",[72,73],"Cystic Fibrosis (CF)","Bronchiectasis Adult",[75,76,77,78,79,80,81,82,83,84,85],"cystic fibrosis","bronchiectasis","acute","exacerbation","respiratory","pulmonary","observational","prospective","cohort","feasibility","umbrella","2025-12-03",{"date":88,"type":89},"2025-12-17","ACTUAL",{"date":91,"type":89},"2025-09-30",{"date":93,"type":68},"2026-04-30",{"name":5,"class":6},1]