[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100549732":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":28,"centralContacts":33,"locations":24,"responsibleParty":38,"collaborators":24,"id":41,"slug":42,"hasResults":43,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":24,"eligibilityCriteria":47,"healthyVolunteers":48,"sex":49,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":24,"studyType":55,"phases":56,"briefSummary":58,"conditions":59,"keywords":63,"overallStatus":67,"whyStopped":24,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":24},{"fullName":5,"class":6},"University of Illinois at Urbana-Champaign","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"MIND Diet","EXPERIMENTAL","Participants in the active MIND diet group will be asked to consume one ready-to-eat meal per day from Daily Harvest® meal delivery service. The treatment meals will follow MIND diet guidelines and include leafy green vegetables, nuts, legumes, whole grains, berries, and extra virgin olive oil.",[13],"Other: MIND Diet",{"label":15,"type":16,"description":17,"interventionNames":18},"Control Diet","ACTIVE_COMPARATOR","Participants in the control diet group will be asked to consume one ready-to-eat meal per day from Daily Harvest® meal delivery service. The Control group will receive daily meals that are isocaloric with the active\u002Fexperimental meals but will follow a general diet based on the average American diet and Dietary Guidelines for Americans (i.e., vegetables, fruits, nuts, whole grains, and unsaturated fats).",[19],"Other: Control Diet",[21,25],{"type":6,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"Daily meals designed to increase adherence to the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) dietary pattern.",[9],null,{"type":6,"name":15,"description":26,"armGroupLabels":27,"otherNames":24},"Daily meals designed to increase fruit, vegetable, and whole grain intake consistent with a healthy American diet.",[15],[29],{"name":30,"affiliation":31,"role":32},"Naiman Khan, PhD","University of Illinois Urbana-Champaign","PRINCIPAL_INVESTIGATOR",[34],{"name":30,"role":35,"phone":36,"phoneExt":24,"email":37},"CONTACT","217 300 1667","nakhan2@illinois.edu",{"type":32,"investigatorFullName":39,"investigatorTitle":40,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Naiman Khan","Associate Professor","100549732","nutritional-intervention-for-sustaining-health-nurish-trial-100549732",false,"NCT06437860","Nutritional Intervention for Sustaining Health (NURISH) Trial","Nutritional Intervention for Sustaining Health (NURISH) Trial: Examining the Effects of the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) on Cognitive Performance, Metabolic Health, and Nutrient Status.","Inclusion Criteria:\n\n* 45-64 years of age\n* 20\u002F20 or corrected vision\n* No food allergies or intolerances\n* Not pregnant, lactating, or have given birth in the past 12 months\n* Do not smoke, use tobacco, or abuse drugs\n* Absence of liver or gastrointestinal diseases (i.e., primary biliary cirrhosis or gallbladder disease, chronic constipation, diarrhea, Crohn's disease, celiac disease, ulcerative colitis, irritable bowel syndrome, diverticulosis, stomach or duodenal ulcers), hepatitis, HIV, and cancer\n* Not currently taking oral hypoglycemic agents, or insulin\n* No history of malabsorptive or bariatric surgery\n* Cognitively intact with no prior diagnosis of neurological disease (i.e., mild cognitive impairment, Alzheimer's disease, vascular dementia, and\u002For Asperger's syndrome)\n* Able to consume the study meals\n* Not enrolled in another dietary, exercise, or medication study during the study\n\nExclusion Criteria:\n\n* Non-consent of participant\n* Above 64 or below 45 years of age\n* Vision not 20\u002F20 or corrected\n* Food allergies or intolerances\n* Pregnant, lactating, or have given birth in the past 12 months\n* Smoke, use tobacco, or abuse drugs\n* Prior diagnosis of liver or gastrointestinal disease (i.e., primary biliary cirrhosis or gallbladder disease, chronic constipation, diarrhea, Crohn's disease, celiac disease, ulcerative colitis, irritable bowel syndrome, diverticulosis, stomach or duodenal ulcers), hepatitis, HIV, or cancer\n* Currently taking oral hypoglycemic agents or insulin\n* History of malabsorptive or bariatric surgery\n* Cognitively impaired and\u002For prior diagnosis of neurological disease (i.e., mild cognitive impairment, Alzheimer's disease, vascular dementia, and\u002For Asperger's syndrome)\n* Unable to consume the study meals\n* Concurrent enrollment in another dietary, exercise, or medication study",true,"ALL","45 Years","64 Years",{"count":53,"type":54},72,"ESTIMATED","INTERVENTIONAL",[57],"NA","The goal of this clinical trial is to learn if increasing adherence to a Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet pattern improves brain and heart health relative to a healthy control diet in middle-aged adults.The main questions it aims to answer are:\n\nDoes the MIND diet improve cognitive performance and heart health relative to a control diet?\n\nResearchers will compare the MIND diet group to a control (a healthy diet that does not match the MIND diet) to see if the MIND provides more benefit to health.\n\nParticipants will:\n\nConsume one meal that follows the MIND diet or a control meal every day for 3 months Visit the lab before and after the 3 months of meals for tests. Keep a record of the food they eat during the study.",[60,61,62],"Cognitive Change","Metabolic Syndrome, Protection Against","Diet, Healthy",[64,65,66],"Executive function","MIND","Dietary pattern","NOT_YET_RECRUITING","2024-05-24",{"date":70,"type":71},"2024-05-31","ACTUAL",{"date":73,"type":54},"2024-06-03",{"date":75,"type":54},"2027-12-31",{"name":5,"class":6}]