[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100558076":3},{"organization":4,"armGroups":7,"interventions":16,"overallOfficials":22,"centralContacts":26,"locations":10,"responsibleParty":31,"collaborators":10,"id":33,"slug":34,"hasResults":35,"nctId":36,"briefTitle":37,"officialTitle":38,"acronym":39,"eligibilityCriteria":40,"healthyVolunteers":35,"sex":41,"minAge":42,"maxAge":43,"enrollmentInfo":44,"targetDuration":10,"studyType":47,"phases":10,"briefSummary":48,"conditions":49,"keywords":10,"overallStatus":51,"whyStopped":10,"lastUpdateSubmitDate":52,"lastUpdatePostDateStruct":53,"startDateStruct":56,"completionDateStruct":58,"leadSponsor":60,"locationsCount":10},{"fullName":5,"class":6},"Neuronostics Ltd","INDUSTRY",[8,13],{"label":9,"type":10,"description":10,"interventionNames":11},"Epilepsy",null,[12],"Device: BioEP",{"label":14,"type":10,"description":10,"interventionNames":15},"Non-epilepsy",[12],[17],{"type":18,"name":19,"description":20,"armGroupLabels":21,"otherNames":10},"DEVICE","BioEP","All patient's EEG will have the BioEP score conducted on it",[9,14],[23],{"name":24,"affiliation":5,"role":25},"Milaana Mainstone","STUDY_DIRECTOR",[27],{"name":24,"role":28,"phone":29,"phoneExt":10,"email":30},"CONTACT","+4401174572292","m.mainstone@neuronostics.com",{"type":32,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100558076","oasis-retrospective-analysis-on-eegs-for-identifying-seizure-susceptibility-in-paediatrics-using-biomarkers-100558076",false,"NCT06546410","OASIS: RetrOspective Analysis on EEGs for Identifying Seizure Susceptibility in paediatrIcs Using biomarkerS","A Retrospective Multisite Analysis of Routinely Collected Outpatient EEGs for Identifying Seizure Susceptibility in Paediatric Epilepsy Using Computational Biomarkers.","OASIS","Inclusion Criteria:\n\n* ≥2-\\\u003C18 years age.\n* Patients who have had a confirmed epilepsy diagnosis for ≥1+ year.\n* Non contributary first EEG: including routine EEG, sleep EEG (natural, melatonin induced, sleep deprived), 24-hour ambulatory EEG.\n* Patients who have been diagnosed with a self-limited and or focal epilepsy \\[\\*\\] who have had a first non-contributary (no IEDS present, negative) outpatient EEG.\n* Patients who have been diagnosed with idiopathic generalised epilepsy \\[†\\] who have had a first non-contributary (no IEDS present, negative) routine EEG.\n* Neurodiverse patients with epilepsy can be included in the study \\[‡\\]\n* Patients with epilepsy and co-morbidities can be included in the study (anxiety, mood disorders etc)\n* Controls should be EEGs taken from patients who have been referred for a paroxysmal disorder, received an EEG as part of their diagnostic work up and subsequently received an alternate diagnosis. Epilepsy should have been excluded from their differential diagnosis and the alternate diagnosis should have remained stable for ≥1+ year.\n\nExclusion Criteria:\n\n* Developmental and\u002For epileptic encephalopathies \\[§\\]\n* Patients with global development delay of unknown origin.\n* Patients with profound and multiple intellectual disabilities\n* Participants with a known hepatic\u002Frenal encephalopathy.\n* Patient diagnosed with possible NEAD and epilepsy (dual diagnosis).\n* Participants taking part in another Clinical Trial of an Investigational Medicinal Product (CTIMP) (qualitative\u002Fobservational studies are acceptable).\n* Patients with any breaches of skull (plates, burr holes, shrapnel).","ALL","2 Years","16 Years",{"count":45,"type":46},500,"ESTIMATED","OBSERVATIONAL","The goal of this retrospective study is to validate a set of computational biomarkers (BioEP) for seizure susceptibility on retrospective routinely collected non-contributory EEGs in paediatric participants with epilepsy. The main objectives are:\n\nPrimary:\n\nTo validate a set of computational biomarkers (BioEP) for seizure susceptibility on retrospective routinely collected non-contributory EEGs in paediatric participants with epilepsy.\n\nSecondary:\n\nTo examine whether the use of BioEP could support a more efficient patient pathway to diagnosis (thus adding economic value), by reducing time to final diagnosis and\u002For the number of clinical appointments needed",[9,50],"Epilepsy in Children","NOT_YET_RECRUITING","2024-08-06",{"date":54,"type":55},"2024-08-09","ACTUAL",{"date":57,"type":46},"2025-01-01",{"date":59,"type":46},"2026-01-01",{"name":5,"class":6}]