[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100553672":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":12,"locations":7,"responsibleParty":18,"collaborators":7,"id":20,"slug":21,"hasResults":22,"nctId":23,"briefTitle":24,"officialTitle":25,"acronym":7,"eligibilityCriteria":26,"healthyVolunteers":27,"sex":28,"minAge":29,"maxAge":30,"enrollmentInfo":31,"targetDuration":7,"studyType":34,"phases":7,"briefSummary":35,"conditions":36,"keywords":38,"overallStatus":44,"whyStopped":7,"lastUpdateSubmitDate":45,"lastUpdatePostDateStruct":46,"startDateStruct":49,"completionDateStruct":51,"leadSponsor":53,"locationsCount":7},{"fullName":5,"class":6},"Peking University First Hospital","OTHER",null,[9],{"name":10,"affiliation":5,"role":11},"Shanshan Yang, Dr","STUDY_CHAIR",[13],{"name":10,"role":14,"phone":15,"phoneExt":16,"email":17},"CONTACT","0086-10-83575051","86-10-83575051","shanshanyangssy@163.com",{"type":19,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100553672","objective-study-on-tongue-diagnosis-of-chronic-atrophic-gastritis-100553672",false,"NCT06489132","Objective Study on Tongue Diagnosis of Chronic Atrophic Gastritis","Objective Study on Tongue Diagnosis of Precancerous Lesions of Chronic Atrophic Gastritis and Construction of Prediction Model","Inclusion Criteria:\n\n( 1 ) Upper gastrointestinal endoscopy was performed within 3 months ; ( 2 ) Patients with chronic atrophic gastritis diagnosed by gastroscopy and pathological examination ; ( 3 ) Age 40-70 years old, gender unlimited ; ( 4 ) agreed to collect tongue image and accept follow-up ; ( 5 ) Volunteered to participate in this study and signed informed consent.\n\nExclusion Criteria:\n\n( 1 ) those who cannot cooperate with standardized tongue image collection and data collection ; ( 2 ) patients with tongue scraping, tongue coating or abnormal tongue extension ; ( 3 ) Suspected gastric malignant tendency or gastric tumor and history of gastric surgery ; ( 4 ) Have hepatitis, syphilis, HIV, schistosomiasis and other known infectious diseases ; ( 5 ) patients with severe heart, liver, kidney, blood diseases and malignant tumors ; ( 6 ) Combined with acute respiratory tract infection, active peptic ulcer and other acute diseases ; ( 7 ) Patients who used antibiotics, acid inhibitors and microecological regulators within 1 month ; ( 8 ) long-term use of immunosuppressive agents, hormones and other drugs ; ( 9 ) pregnant or lactating women.",true,"ALL","40 Years","70 Years",{"count":32,"type":33},498,"ESTIMATED","OBSERVATIONAL","Chronic atrophic gastritis with intestinal metaplasia or dysplasia is called precancerous lesions of gastric cancer ( PLGC ). It is an important stage in the transformation of normal mucosa to gastric cancer and is significantly associated with the risk of gastric cancer. Early identification of PLGC high-risk groups is the focus of prevention and treatment of gastric cancer. Gastroscopy and pathological examination are the key means to diagnose PLGC. However, due to the invasiveness, high cost, strong professional operability and traumatic pathological sampling, the application of gastroscopy is greatly limited, and the predictive significance of serum markers for the occurrence and prognosis of PLGC is limited. The current PLGC monitoring methods are not targeted enough, and there is still a lack of effective risk prediction models for PLGC. New screening methods are needed to improve the early diagnosis rate of PLGC. Tongue diagnosis is simple, convenient, easy and inexpensive. It can dynamically monitor the risk of PLGC in patients with chronic atrophic gastritis in early real time, and timely formulate individualized intervention measures, which is of great significance for improving the prognosis of patients, controlling medical expenses and truncating disease progression. Based on the objectification of tongue diagnosis, it may become an important method for screening PLGC from the perspective of macroscopic tongue image characteristics and microscopic tongue coating flora.",[37],"Chronic Atrophic Gastritis",[39,40,41,42,43],"Gastric precancerous lesions","tongue diagnosis","objectification","tongue coating flora","prediction model","NOT_YET_RECRUITING","2024-07-04",{"date":47,"type":48},"2024-07-05","ACTUAL",{"date":50,"type":33},"2024-07",{"date":52,"type":33},"2026-03",{"name":5,"class":6}]