[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100557331":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":19,"locations":29,"responsibleParty":74,"collaborators":10,"id":76,"slug":77,"hasResults":78,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":10,"eligibilityCriteria":82,"healthyVolunteers":78,"sex":83,"minAge":84,"maxAge":10,"enrollmentInfo":85,"targetDuration":10,"studyType":88,"phases":10,"briefSummary":89,"conditions":90,"keywords":10,"overallStatus":32,"whyStopped":10,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"Tianjin Medical University Second Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"PCa Patients With Visceral Metastasis",null,"Prostate cancer patients with visceral metastasis.",[13],"Other: Building Organoid-on-chips models",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Building Organoid-on-chips models","This project obtains surgical or biopsy samples from prostate cancer patients with visceral metastasis for the construction of organoids.",[9],[20,25],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Haitao Wang, Ph.D","CONTACT","+86-022-88326385","peterrock2000@126.com",{"name":26,"role":22,"phone":27,"phoneExt":10,"email":28},"Jinhuan Wang, Ph.D","+86-022-88326610","wjhhappy2008@163.com",[30,60],{"facility":31,"status":32,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Tianjin Medical Unversity Second Hospital","RECRUITING","Tianjin","Tianjin Municipality","300211","China","CN",{"type":39,"coordinates":40},"Point",[41,42],117.17667,39.14222,{"lat":42,"lon":41},[45,48,52,54,56,58],{"name":46,"role":22,"phone":47,"phoneExt":10,"email":24},"Haitao Wang","+86-02288326610",{"name":49,"role":22,"phone":50,"phoneExt":10,"email":51},"Lili Wang","+86-13516108466","wangliliaigang@163.com",{"name":46,"role":53,"phone":10,"phoneExt":10,"email":10},"PRINCIPAL_INVESTIGATOR",{"name":49,"role":55,"phone":10,"phoneExt":10,"email":10},"SUB_INVESTIGATOR",{"name":57,"role":55,"phone":10,"phoneExt":10,"email":10},"Dingkun Hou",{"name":59,"role":55,"phone":10,"phoneExt":10,"email":10},"Jinhuan Wang",{"facility":31,"status":32,"city":33,"state":34,"zip":10,"country":36,"countryCode":37,"cosmosGeoPoint":61,"geoPoint":63,"contacts":64},{"type":39,"coordinates":62},[41,42],{"lat":42,"lon":41},[65,66,68,69,70,71,72],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},{"name":67,"role":22,"phone":27,"phoneExt":10,"email":51},"Lili Wang, MM",{"name":46,"role":53,"phone":10,"phoneExt":10,"email":10},{"name":49,"role":55,"phone":10,"phoneExt":10,"email":10},{"name":59,"role":55,"phone":10,"phoneExt":10,"email":10},{"name":57,"role":55,"phone":10,"phoneExt":10,"email":10},{"name":73,"role":55,"phone":10,"phoneExt":10,"email":10},"Lei Wang",{"type":75,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100557331","observation-of-clinical-consistency-of-organoid-chips-drug-sensitivity-in-chemotherapy-for-pca-with-visceral-metastasis-100557331",false,"NCT06536725","Observation of Clinical Consistency of Organoid-chips Drug Sensitivity in Chemotherapy for PCa With Visceral Metastasis","Observation of Clinical Consistency of Organoid-on-chips Drug Sensitivity Detection in Chemotherapy for Prostate Cancer Patients With Visceral Metastasis","Inclusion Criteria:\n\n1. Patients with visceral metastasis of prostate cancer diagnosed clinically or pathologically;\n2. Age ≥ 18 years old;\n3. ECOG score ≤ 2 points or ECOG score 3-4 points due to tumor progression;\n4. Normal liver and kidney function, serum transaminase ALT\\\u003C66 U\u002FL, AST\\\u003C36 U\u002FL, total bilirubin\\\u003C22 umol\u002FL, creatinine\\\u003C106 umol\u002FL, urea nitrogen\\\u003C6.1 mmol\u002FL; Normal bone marrow function: neutrophil count ≥ 1800\u002Fmm3 and platelet count ≥ 100000\u002Fmm3;\n5. Can obtain surgical or biopsy samples;\n6. Patients voluntarily join this study and sign an informed consent form.\n\nExclusion Criteria:\n\n1. Patients with severe heart, liver, kidney, and peripheral nervous system diseases, as well as autoimmune diseases such as hyperthyroidism and hypothyroidism; Systemic lupus erythematosus, etc;\n2. Patients who are unable to obtain tissue samples;\n3. Subjects with active pulmonary tuberculosis (TB);\n4. Subjects who are preparing for or have previously undergone tissue\u002Forgan transplantation;\n5. Exclusion criteria are not listed, but the researchers believe that patients who are not suitable to participate in this clinical study.","MALE","18 Years",{"count":86,"type":87},35,"ESTIMATED","OBSERVATIONAL","This project plans to establish an organoid chip model of prostate cancer patients with internal organ metastasis from surgical or biopsy tissue sources, and test the sensitivity of commonly used chemotherapy drugs based on organoid chip drug sensitivity testing technology to screen out sensitive individualized treatment plans.",[91,92],"Prostate Cancer","Organoid","2024-08-02",{"date":95,"type":96},"2024-08-05","ACTUAL",{"date":98,"type":96},"2024-06-01",{"date":100,"type":87},"2025-12-31",{"name":5,"class":6},2]