[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100644886":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":7,"locations":7,"responsibleParty":8,"collaborators":10,"id":14,"slug":15,"hasResults":16,"nctId":17,"briefTitle":18,"officialTitle":19,"acronym":20,"eligibilityCriteria":21,"healthyVolunteers":16,"sex":22,"minAge":23,"maxAge":7,"enrollmentInfo":24,"targetDuration":7,"studyType":27,"phases":7,"briefSummary":28,"conditions":29,"keywords":7,"overallStatus":31,"whyStopped":7,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":7},{"fullName":5,"class":6},"Prenosis, Inc.","INDUSTRY",null,{"type":9,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR",[11],{"name":12,"class":13},"Biomedical Advanced Research and Development Authority","FED","100644886","observational-non-interventional-biomarker-and-endotyping-study-100644886",false,"NCT07675265","Observational, Non-interventional Biomarker and Endotyping Study","Observational Biomarker Study for the Evaluation of Response and Validation of Endotypes in Acute Respiratory Distress Syndrome","OBSERVE-ARDS","Inclusion Criteria:\n\n* Age ≥18 years\n* ARDS Diagnosis (New Global Definition of ARDS)\n* Timing: Acute onset within 7 days\n* Radiology: Bilateral pulmonary opacities\n* Hypoxia:\n\nNon-intubated ARDS: PaO2:FIO2\\\u003C300mmHg or SpO2:FIO2\\\u003C315 (if SpO2\\\u003C97%) on HFNO with flow of \\>30 L\u002Fmin or NIV\u002FCPAP with at least 5 cm H2O end-expiratory pressure; or Intubated ARDS: PaO2:FIO2\\\u003C300 mm Hg or SpO2:FIO2\\\u003C315 (if SpO2\\\u003C97%)\n\n* ICU admission\n* Enrolled within 72 hours of meeting inclusion criteria\n\nExclusion Criteria:\n\n• Primary cardiogenic pulmonary edema","ALL","18 Years",{"count":25,"type":26},1200,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to establish a centralized ARDS biorepository of longitudinal biospecimens and harmonized clinical data, develop unsupervised, therapy-agnostic endotyping algorithms, and develop unsupervised, therapy-specific treatment-prediction algorithms over a 24 month period.",[30],"ARDS (Acute Respiratory Distress Syndrome)","NOT_YET_RECRUITING","2026-06-23",{"date":34,"type":35},"2026-06-30","ACTUAL",{"date":37,"type":26},"2026-07",{"date":39,"type":26},"2029-03",{"name":5,"class":6}]