[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100513567":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":20,"locations":26,"responsibleParty":146,"collaborators":10,"id":148,"slug":149,"hasResults":150,"nctId":151,"briefTitle":152,"officialTitle":153,"acronym":154,"eligibilityCriteria":155,"healthyVolunteers":150,"sex":156,"minAge":157,"maxAge":10,"enrollmentInfo":158,"targetDuration":161,"studyType":162,"phases":10,"briefSummary":163,"conditions":164,"keywords":167,"overallStatus":29,"whyStopped":10,"lastUpdateSubmitDate":172,"lastUpdatePostDateStruct":173,"startDateStruct":176,"completionDateStruct":178,"leadSponsor":180,"locationsCount":181},{"fullName":5,"class":6},"Sirtex Medical","INDUSTRY",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients with unresectable HCC or unresectable liver metastases from mCRC",null,"This cohort will include patients with unresectable HCC or unresectable liver metastases from mCRC refractory to or intolerant to chemotherapy, who have been prescribed selective internal radiation therapy (SIRT) with SIR-Spheres per medical decision.",[13],"Device: SIRT",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DEVICE","SIRT","Selective internal radiation therapy with SIR-Spheres Y90 resin microspheres.",[9],[21],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Janet Bell","CONTACT","781-721-3840","jbell@sirtex.com",[27,45,59,72,87,98,110,125,137],{"facility":28,"status":29,"city":30,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Hôpital Beaujon","RECRUITING","Clichy","Cedex","92118","France","FR",{"type":36,"coordinates":37},"Point",[38,39],2.30952,48.90018,{"lat":39,"lon":38},[42],{"name":43,"role":44,"phone":10,"phoneExt":10,"email":10},"Mohamed Bouattour","PRINCIPAL_INVESTIGATOR",{"facility":46,"status":47,"city":48,"state":49,"zip":50,"country":33,"countryCode":34,"cosmosGeoPoint":51,"geoPoint":55,"contacts":56},"Hopital Henri Mondor","NOT_YET_RECRUITING","Créteil","Paris","94000",{"type":36,"coordinates":52},[53,54],2.46569,48.79266,{"lat":54,"lon":53},[57],{"name":58,"role":44,"phone":10,"phoneExt":10,"email":10},"Hélène Regnault",{"facility":60,"status":29,"city":61,"state":62,"zip":63,"country":33,"countryCode":34,"cosmosGeoPoint":64,"geoPoint":68,"contacts":69},"Hospices Civils de Lyon HCL Centre Hospitalier Lyon-Sud","Pierre-Bénite","Rhône","69495",{"type":36,"coordinates":65},[66,67],4.82424,45.70359,{"lat":67,"lon":66},[70],{"name":71,"role":44,"phone":10,"phoneExt":10,"email":10},"Nicolas Jacquet-Francillon",{"facility":73,"status":47,"city":74,"state":75,"zip":76,"country":77,"countryCode":78,"cosmosGeoPoint":79,"geoPoint":83,"contacts":84},"Hospital Universitario Puerta de Hierro - Majadahonda","Majadahonda","Madrid","28220","Spain","ES",{"type":36,"coordinates":80},[81,82],-3.87182,40.47353,{"lat":82,"lon":81},[85],{"name":86,"role":44,"phone":10,"phoneExt":10,"email":10},"Lourdes Gutierrez",{"facility":88,"status":47,"city":75,"state":10,"zip":89,"country":77,"countryCode":78,"cosmosGeoPoint":90,"geoPoint":94,"contacts":95},"Hospital General Universitario Gregorio Marañon","28009",{"type":36,"coordinates":91},[92,93],-3.70256,40.4165,{"lat":93,"lon":92},[96],{"name":97,"role":44,"phone":10,"phoneExt":10,"email":10},"Pilar Garcia Alfonso",{"facility":99,"status":47,"city":100,"state":10,"zip":101,"country":77,"countryCode":78,"cosmosGeoPoint":102,"geoPoint":106,"contacts":107},"Hospital Clinico Universitario de Valencia","Valencia","46010",{"type":36,"coordinates":103},[104,105],-0.37966,39.47391,{"lat":105,"lon":104},[108],{"name":109,"role":44,"phone":10,"phoneExt":10,"email":10},"Paloma Lluch",{"facility":111,"status":47,"city":112,"state":113,"zip":114,"country":115,"countryCode":116,"cosmosGeoPoint":117,"geoPoint":121,"contacts":122},"The Christie Hospital","Manchester","Lancashire","M20 4BX","United Kingdom","UK",{"type":36,"coordinates":118},[119,120],-2.23743,53.48095,{"lat":120,"lon":119},[123],{"name":124,"role":44,"phone":10,"phoneExt":10,"email":10},"Saifee Mullamitha",{"facility":126,"status":47,"city":127,"state":10,"zip":128,"country":115,"countryCode":116,"cosmosGeoPoint":129,"geoPoint":133,"contacts":134},"Kings College Hospital","London","SE5 9RS",{"type":36,"coordinates":130},[131,132],-0.12574,51.50853,{"lat":132,"lon":131},[135],{"name":136,"role":44,"phone":10,"phoneExt":10,"email":10},"Paul Ross",{"facility":138,"status":47,"city":127,"state":10,"zip":139,"country":115,"countryCode":116,"cosmosGeoPoint":140,"geoPoint":142,"contacts":143},"Hammersmith Hospital","W12 OHS",{"type":36,"coordinates":141},[131,132],{"lat":132,"lon":131},[144],{"name":145,"role":44,"phone":10,"phoneExt":10,"email":10},"Rohini Sharma",{"type":147,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100513567","observational-sir-spheres-study-for-the-treatment-of-unresectable-liver-tumors-sirtain-registry-100513567",false,"NCT05967143","Observational SIR-Spheres Study for the Treatment of Unresectable Liver Tumors (SIRtain Registry)","Observational Study to Assess Real-World Outcomes in Patients With Unresectable Liver Tumors Initiating Treatment With SIR-Spheres (Y-90 Resin Microspheres) (SIRtain Registry)","SIRtain","Inclusion Criteria:\n\n* Age 18 years or older\n* Confirmed diagnosis of:\n* Unresectable hepatocellular carcinoma (HCC) Or\n* Unresectable liver metastases from colorectal cancer (mCRC) refractory to or intolerant to chemotherapy\n* Identified as a candidate for SIR-Spheres treatment as deemed appropriate during the normal course of practice\n* Planned to receive SIR-Spheres treatment to the liver for the first time\n* Provision of signed patient informed consent\n\nExclusion Criteria:\n\n* Prior radiation treatment to the liver\n\nCaveat:\n\nSequential selective internal radiation therapy (SIRT) treatment is allowed\n\n* Patients participating in any interventional clinical trial with an investigational product, device, or procedure\n* Need for surrogate consent. Patients who are not able to consent on behalf of themselves are not eligible.","ALL","18 Years",{"count":159,"type":160},845,"ESTIMATED","2 Years","OBSERVATIONAL","This registry seeks to prospectively gather a large repository of comprehensive observational data reflecting routine use of SIR-Spheres in patients diagnosed with unresectable HCC or unresectable liver metastases from mCRC refractory to or intolerant to chemotherapy, in order to assess clinical response in a real-world setting and further validate the safe and appropriate use of SIR-Spheres",[165,166],"Unresectable Hepatocellular Carcinoma (HCC)","Liver Metastases From Colorectal Cancer (mCRC)",[168,169,170,171,17],"Liver metastases from colorectal cancer (mCRC)","Unresectable Hepatocellular carcinoma (HCC)","SIR-Spheres microspheres","Y-90 resin microspheres","2024-11-26",{"date":174,"type":175},"2024-11-27","ACTUAL",{"date":177,"type":175},"2023-06-19",{"date":179,"type":160},"2029-06",{"name":5,"class":6},9]