[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100517929":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":10,"centralContacts":10,"locations":27,"responsibleParty":71,"collaborators":10,"id":73,"slug":74,"hasResults":75,"nctId":76,"briefTitle":77,"officialTitle":77,"acronym":10,"eligibilityCriteria":78,"healthyVolunteers":75,"sex":79,"minAge":80,"maxAge":10,"enrollmentInfo":81,"targetDuration":10,"studyType":84,"phases":10,"briefSummary":85,"conditions":86,"keywords":89,"overallStatus":91,"whyStopped":10,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Northwell Health","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Newly-diagnosed mild OSA - initiating CPAP treatment",null,"Subjects with newly-diagnosed mild obstructive sleep apnea being treated with CPAP undergoing clinical observation\u002Fdiagnostic evaluation for detection and tracking of NTG.",[13],"Other: Clinical observation, diagnostic testing",{"label":15,"type":10,"description":16,"interventionNames":17},"Newly-diagnosed moderate OSA - initiating CPAP treatment","Subjects with newly-diagnosed moderate obstructive sleep apnea being treated with CPAP undergoing clinical observation\u002Fdiagnostic evaluation for detection and tracking of NTG.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Newly-diagnosed severe OSA - initiating CPAP treatment","Subjects with newly-diagnosed severe obstructive sleep apnea being treated with CPAP undergoing clinical observation\u002Fdiagnostic evaluation for detection and tracking of NTG.",[13],[23],{"type":6,"name":24,"description":25,"armGroupLabels":26,"otherNames":10},"Clinical observation, diagnostic testing","Glaucoma evaluation including structural and functional diagnostic testing at baseline and 3 subsequent follow-up visits over a period of 9 months",[9,15,19],[28,58],{"facility":29,"status":10,"city":30,"state":30,"zip":31,"country":32,"countryCode":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"Manhattan Eye, Ear, & Throat Hospital","New York","10065","United States","US",{"type":35,"coordinates":36},"Point",[37,38],-74.00597,40.71427,{"lat":38,"lon":37},[41,46,49,52,54,56],{"name":42,"role":43,"phone":44,"phoneExt":10,"email":45},"Andrew Tirsi, MD","CONTACT","201-982-4168","atirsi@northwell.edu",{"name":47,"role":48,"phone":10,"phoneExt":10,"email":10},"Celso Tello, MD","PRINCIPAL_INVESTIGATOR",{"name":50,"role":51,"phone":10,"phoneExt":10,"email":10},"Stephen Obstbaum, MD","SUB_INVESTIGATOR",{"name":53,"role":51,"phone":10,"phoneExt":10,"email":10},"Sung Chul Park, MD",{"name":55,"role":51,"phone":10,"phoneExt":10,"email":10},"Yosef Krespi, MD",{"name":57,"role":51,"phone":10,"phoneExt":10,"email":10},"Tirsi Andrew, MD",{"facility":29,"status":10,"city":30,"state":30,"zip":31,"country":32,"countryCode":33,"cosmosGeoPoint":59,"geoPoint":61,"contacts":62},{"type":35,"coordinates":60},[37,38],{"lat":38,"lon":37},[63,64,66,67,68,69,70],{"name":42,"role":43,"phone":44,"phoneExt":10,"email":45},{"name":65,"role":43,"phone":10,"phoneExt":10,"email":45},"Tirsi",{"name":47,"role":48,"phone":10,"phoneExt":10,"email":10},{"name":50,"role":51,"phone":10,"phoneExt":10,"email":10},{"name":53,"role":51,"phone":10,"phoneExt":10,"email":10},{"name":55,"role":51,"phone":10,"phoneExt":10,"email":10},{"name":57,"role":51,"phone":10,"phoneExt":10,"email":10},{"type":72,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100517929","obstructive-sleep-apnea-as-a-risk-factor-for-normal-tension-glaucoma-and-a-crucial-step-in-preventing-blindness-100517929",false,"NCT06023927","Obstructive Sleep Apnea as a Risk Factor for Normal Tension Glaucoma and a Crucial Step in Preventing Blindness","Inclusion Criteria:\n\n* Newly diagnosed subjects with OSA that will undergo CPAP treatment.\n* At least 21 years of age\n* Best corrected vision of 20\u002F40 or better, spherical Rx \\\u003C ± 6.0 Diopter, and cylinder \\\u003C-3.0D\n* Ability to follow instructions, and intent to complete all study visits\n\nExclusion Criteria:\n\n* High Rx \\>± 6.0D and cylinder \\> -3.0D\n* Narrow angle glaucoma\n* History of any of the following: severe eye trauma, ocular inflammation, previous intraocular surgery except for uncomplicated cataract extraction with posterior chamber intraocular lens implantation.\n* Any medical or ocular condition which is not appropriate for participation in the trial (Diabetic retinopathy, and other retinal changes preventing reliable optic disc evaluation) Hypersensitivity to any component of altafluor benox","ALL","21 Years",{"count":82,"type":83},100,"ESTIMATED","OBSERVATIONAL","The purpose of this research study is to learn more about the relationship between Obstructive Sleep Apnea (OSA) and Normal Tension Glaucoma (NTG). OSA is a nighttime disorder of the upper airway that causes an intermittent lack of oxygen while sleeping. NTG is a type of glaucoma that occurs despite the normal intraocular pressure levels, making its detection more difficult. Left untreated, irreversible optic nerve damage and extensive vision loss can result. Previous research has shown some evidence between OSA and the development of NTG. The investigators are researching whether undergoing treatment for OSA would help to improve the vascular health to the retina, and in effect, improve the early signs of visual dysfunction seen with diagnostic testing.",[87,88],"Normal Tension Glaucoma","Obstructive Sleep Apnea",[90],"Glaucoma, obstructive sleep apnea Syndrome","NOT_YET_RECRUITING","2025-06-05",{"date":94,"type":95},"2025-06-10","ACTUAL",{"date":97,"type":83},"2025-09-02",{"date":99,"type":83},"2028-09-01",{"name":5,"class":6},2]