[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100474378":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":11,"centralContacts":20,"locations":30,"responsibleParty":47,"collaborators":11,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":11,"eligibilityCriteria":57,"healthyVolunteers":58,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":11,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":74,"overallStatus":78,"whyStopped":11,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"University of California, San Diego","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Automatic Positive Airway Pressure (APAP) device","EXPERIMENTAL",null,[13],"Device: Automatic Positive Airway Pressure (APAP)",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":11},"DEVICE","Automatic Positive Airway Pressure (APAP)","If eligible, participants will be given a clinical Automatic Positive Airway Pressure (APAP) device for up to 3 months, while they are waiting for their clinical evaluation from a sleep physician. The APAP device will we will be using is the ResMed Airsense 11 Autoset. APAP is a smart positive airway pressure (PAP) device, where the pressure changes as needed to provide optimal pressure to splint the upper airway. Dr. Lee and Dr. Schmickl will oversee management of the device.\n\nDuring the first month of APAP use, individuals will participate in weekly phone calls or in-person visits to ensure optimal adherence and troubleshoot any issues (improper mask fitting, discomfort, etc) that may arise.",[9],[21,26],{"name":22,"role":23,"phone":24,"phoneExt":11,"email":25},"Ellen Lee, M.D.","CONTACT","858-314-8126","eel013@health.ucsd.edu",{"name":27,"role":23,"phone":28,"phoneExt":11,"email":29},"Stephanie Ibrahim","(858) 255-0721","sribrahim@health.ucsd.edu",[31],{"facility":32,"status":11,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"UCSD","La Jolla","California","92037","United States","US",{"type":39,"coordinates":40},"Point",[41,42],-117.2742,32.84727,{"lat":42,"lon":41},[45],{"name":27,"role":23,"phone":46,"phoneExt":11,"email":29},"858-255-0721",{"type":48,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Ellen Lee","Assistant Professor","100474378","obstructive-sleep-apnea-treatment-in-serious-mental-illness-100474378",false,"NCT05457127","Obstructive Sleep Apnea Treatment in Serious Mental Illness","Obstructive Sleep Apnea Treatment in People Aging With Serious Mental Illness","Inclusion Criteria:\n\nControl participants:\n\n* lifetime absence of major psychiatric illness\n* 40 to 70 years old\n* be at risk for or have a diagnosis of obstructive sleep apnea\n\nFor participants with serious mental illness:\n\n* diagnosis of schizophrenia, schizoaffective disorder, or bipolar disorder\n* must not be conservatized\n* 40 - 70 years old\n* be at risk or have a diagnosis of obstructive sleep apnea.\n\nExclusion Criteria:\n\n* DSM-IV-TR diagnosis of active alcohol or other substance abuse or dependence in the 3 months preceding enrollment. This will be self-report.\n* Diagnosis of dementia, mental retardation, or other neurological or medical conditions known to affect neurophysiologic or neurocognitive functioning, or autoimmune disease\n* Other major DSM-IV-TR Axis I Disorder\n* Medical problems that interfere with a participant's ability to complete the assessments\n* Plans to move out of the San Diego county area within the following 6 months\n* Diagnosis of OSA and currently receiving APAP, CPAP, or any treatment from a physician.",true,"ALL","40 Years","70 Years",{"count":63,"type":64},300,"ESTIMATED","INTERVENTIONAL",[67],"NA","Serious mental illnesses (SMI) like schizophrenia and bipolar disorder are two of the most disabling and costly chronic illnesses worldwide. A high proportion of adults with schizophrenia and bipolar disorder have sleep disorders, like obstructive sleep apnea (OSA), but tend to be underdiagnosed and undertreated compared to the general population. This study aims to examine feasibility, acceptance, and impact of OSA treatment and how it affects cognitive function in people with SMI.",[70,71,72,73],"Schizoaffective Disorder","Schizophrenia","Bipolar Disorder","Obstructive Sleep Apnea of Adult",[75,76,77],"Serious mental illness","aging","positive airway pressure","NOT_YET_RECRUITING","2024-07-08",{"date":81,"type":82},"2024-07-10","ACTUAL",{"date":84,"type":64},"2025-01-01",{"date":86,"type":64},"2026-11",{"name":5,"class":6},1]