[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100497633":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":33,"centralContacts":37,"locations":46,"responsibleParty":66,"collaborators":69,"id":72,"slug":73,"hasResults":74,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":32,"eligibilityCriteria":78,"healthyVolunteers":79,"sex":80,"minAge":81,"maxAge":82,"enrollmentInfo":83,"targetDuration":32,"studyType":86,"phases":87,"briefSummary":89,"conditions":90,"keywords":94,"overallStatus":48,"whyStopped":32,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":110},{"fullName":5,"class":6},"Massachusetts General Hospital","OTHER",[8,14,18,22],{"label":9,"type":10,"description":11,"interventionNames":12},"Healthy cornea","EXPERIMENTAL","Optical imaging of the cornea in healthy subjects",[13],"Device: Optical imaging of the tissues",{"label":15,"type":10,"description":16,"interventionNames":17},"Healthy skin","Optical imaging of the skin in healthy subjects",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Healthy gingiva","Optical imaging of the gingiva in healthy subjects",[13],{"label":23,"type":10,"description":24,"interventionNames":25},"Keratoconus cornea","Optical imaging of the cornea in mild and moderate keratoconus",[13],[27],{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"DEVICE","Optical imaging of the tissues","OCT vibrography",[9,19,15,23],null,[34],{"name":35,"affiliation":5,"role":36},"Seok-Hyun Yun, PhD","PRINCIPAL_INVESTIGATOR",[38,43],{"name":39,"role":40,"phone":41,"phoneExt":32,"email":42},"Jing Zhang, PhD","CONTACT","6173730127","jzhang110@mgh.harvard.edu",{"name":35,"role":40,"phone":44,"phoneExt":32,"email":45},"6177688704","syun@mgh.harvard.edu",[47],{"facility":5,"status":48,"city":49,"state":50,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"RECRUITING","Boston","Massachusetts","02114","United States","US",{"type":55,"coordinates":56},"Point",[57,58],-71.05977,42.35843,{"lat":58,"lon":57},[61,63,64],{"name":39,"role":40,"phone":62,"phoneExt":32,"email":42},"617-373-0127",{"name":35,"role":40,"phone":44,"phoneExt":32,"email":45},{"name":35,"role":65,"phone":32,"phoneExt":32,"email":32},"SUB_INVESTIGATOR",{"type":36,"investigatorFullName":67,"investigatorTitle":68,"investigatorAffiliation":5,"oldNameTitle":32,"oldOrganization":32},"Seok Hyun Yun","Professor of Dermatology",[70],{"name":71,"class":6},"Massachusetts Eye and Ear Infirmary","100497633","oct-vibrography-for-biomechanical-properties-of-tissues-100497633",false,"NCT05759780","OCT Vibrography for Biomechanical Properties of Tissues","A Study to Test the Potential of OCT Vibrography for Measuring Biomechanical Properties of Tissues","Group 1:\n\nInclusion criteria:\n\n• Subjects with healthy eyes (age 18 - 75, N = 50)\n\nExclusion criteria:\n\n* Subjects with history of eye diseases, and previous eye surgeries.\n* Subjects with diabetes, glaucoma family history\n* Subjects allergic to anesthetic eyedrop, especially proparacaine\n* Subjects with severe allergy\n* Subjects who have difficulty biting\n* Subjects who have recurrent corneal erosion\n\nGroup 2:\n\nInclusion criteria:\n\n• Subjects with healthy skin (age 18 - 75, N = 10)\n\nExclusion criteria:\n\n• Subjects with open cuts\u002Fsores on the skin, skin infection, or any contagious skin condition\n\nGroup 3:\n\nInclusion criteria:\n\n• Subjects with healthy gingiva (age 18 - 75, N = 10)\n\nExclusion criteria:\n\n• Subjects with open cuts\u002Fsores on the gingiva, gingiva infection, or any contagious gingiva condition\n\nGroup 4:\n\nInclusion criteria:\n\n• Mild or moderate keratoconus subjects (age 18 - 40, N = 20)\n\nExclusion criteria:\n\n• Subjects with K-max above 60 diopters (Pentacam imaging) are excluded",true,"ALL","18 Years","75 Years",{"count":84,"type":85},90,"ESTIMATED","INTERVENTIONAL",[88],"NA","The overall goal of this study is to develop OCT Vibrography (aka OCT elastography) as a novel tool for measuring biomechanical properties of human tissues in vivo.",[91,92,93],"Cornea","Skin Diseases","Gingival Diseases",[95,96,97,98,99,100],"biomechanics","cornea","skin","gingiva","optical coherence tomography","vibrography","2025-10-21",{"date":103,"type":104},"2025-10-23","ACTUAL",{"date":106,"type":104},"2023-08-19",{"date":108,"type":85},"2026-08-28",{"name":5,"class":6},1]