[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100558043":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":10,"centralContacts":22,"locations":28,"responsibleParty":44,"collaborators":10,"id":48,"slug":49,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":10,"eligibilityCriteria":53,"healthyVolunteers":54,"sex":55,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":10,"studyType":61,"phases":10,"briefSummary":62,"conditions":63,"keywords":10,"overallStatus":30,"whyStopped":10,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":74},{"fullName":5,"class":6},"Medical University of Vienna","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Idiopathic intracranial hypertension (Group 1)",null,"24 subjects with idiopathic intracranial hypertension",[13],"Other: Lumbar puncture and administration of medication",{"label":15,"type":10,"description":16,"interventionNames":10},"Healthy control subjects (Group 2)","24 age- and sex-matched control subjects",[18],{"type":6,"name":19,"description":20,"armGroupLabels":21,"otherNames":10},"Lumbar puncture and administration of medication","Patients with idiopathic intracranial hypertension will receive lumbar puncture and will be given medication to reduce intracranial pressure by neurologists. The lumbar puncture and the administration of medication are not part of this study, patients would also receive these without participating in the study.",[9],[23],{"name":24,"role":25,"phone":26,"phoneExt":10,"email":27},"Gerhard Garhöfer","CONTACT","+43 1 40400 29880","gerhard.garhoefer@meduniwien.ac.at",[29],{"facility":5,"status":30,"city":31,"state":10,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"RECRUITING","Vienna","1090","Austria","AT",{"type":36,"coordinates":37},"Point",[38,39],16.37208,48.20849,{"lat":39,"lon":38},[42],{"name":24,"role":25,"phone":43,"phoneExt":10,"email":27},"+43 40400 29880",{"type":45,"investigatorFullName":46,"investigatorTitle":47,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Gerhard Garhofer","Assoc. Prof. Priv. Doz. Dr. med. univ.","100558043","ocular-perfusion-in-patients-with-idiopathic-intracranial-hypertension-100558043",false,"NCT06545981","Ocular Perfusion in Patients With Idiopathic Intracranial Hypertension","Inclusion criteria for patients with idiopathic intracranial hypertension\n\n* Men and Women aged ≥ 18 years\n* Signed informed consent\n* Newly diagnosed idiopathic intracranial hypertension or relapse of idiopathic intracranial hypertension\n* Non-Smokers\n\nInclusion criteria for healthy age- and sex-matched control subjects\n\n* Men and Women aged ≥ 18 years\n* Signed informed consent\n* Normal ophthalmic findings, unless the investigator considers an abnormality to be clinically irrelevant\n* Normal findings in the medical history, unless the investigator considers an abnormality to be clinically irrelevant\n* Non-Smokers\n\nExclusion criteria for patients with idiopathic intracranial hypertension and healthy age- and sex-matched control subjects:\n\n* Blood donation in the three weeks preceding the study\n* Symptoms of a clinically relevant illness in the three weeks preceding the study\n* Ocular inflammation or infection within the last 3 months\n* History or family history of epilepsy\n* Diabetes mellitus type 1 or type 2\n* History or known presence of other cerebral vascular diseases (e.g.: arteriovenous malformation, aneurysm, major artery stenosis or occlusion)\n* History or known presence of intracranial infections (e.g.: meningitis)\n* History or known presence of other neurological diseases (e.g.: brain tumor, hydrocephalus, degenerative diseases)\n* Patients receiving corticosteroids or immunosuppressant therapy\n* Pregnant or breast-feeding women\n* Women of childbearing potential (neither menopausal, nor hysterectomized, nor sterilized) not using effective contraception",true,"ALL","18 Years","90 Years",{"count":59,"type":60},48,"ESTIMATED","OBSERVATIONAL","The proposed study aims to evaluate optic nerve head blood flow and microcirculation in patients with idiopathic intracranial hypertension. For this purpose, optic nerve head blood flow will be examined in patients with IIH before and after therapy and additionally compared with healthy age- and sex-matched control subjects. In addition, other parameters will be measured, in particular retinal blood flow, retinal oxygen saturation and retinal neurovascular coupling.",[64],"Idiopathic Intracranial Hypertension","2024-08-29",{"date":67,"type":68},"2024-08-30","ACTUAL",{"date":70,"type":68},"2024-05-28",{"date":72,"type":60},"2026-08-31",{"name":5,"class":6},1]