[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100513156":3},{"organization":4,"armGroups":7,"interventions":16,"overallOfficials":30,"centralContacts":34,"locations":43,"responsibleParty":62,"collaborators":22,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":71,"eligibilityCriteria":72,"healthyVolunteers":67,"sex":73,"minAge":74,"maxAge":22,"enrollmentInfo":75,"targetDuration":22,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":87,"overallStatus":46,"whyStopped":22,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":103},{"fullName":5,"class":6},"University of Pittsburgh","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Quantitative Sensory Testing","EXPERIMENTAL","Participants with chronic low back pain and a scheduled lumbar medial branch block undergo quantitative sensory testing.",[13,14,15],"Behavioral: Cutaneous Probe","Behavioral: Quantitative Sensory Testing","Behavioral: Computer Tasks",[17,23,26],{"type":18,"name":19,"description":20,"armGroupLabels":21,"otherNames":22},"BEHAVIORAL","Cutaneous Probe","A computer-controlled probe delivers temperatures to the skin to measure pain, offset analgesia and onset hyperalgesia.",[9],null,{"type":18,"name":9,"description":24,"armGroupLabels":25,"otherNames":22},"Standard methods involving pinprick, pressure, heat, and cold applied to the skin are used to measure sensation and pain",[9],{"type":18,"name":27,"description":28,"armGroupLabels":29,"otherNames":22},"Computer Tasks","Quantitative Sensory Testing (QST) and computer tasks are used to measure changes in pain intensity.",[9],[31],{"name":32,"affiliation":5,"role":33},"Benedict J Alter, MD, PhD","PRINCIPAL_INVESTIGATOR",[35,40],{"name":36,"role":37,"phone":38,"phoneExt":22,"email":39},"Maya L Maurer, BS","CONTACT","412-665-8052","mam708@pitt.edu",{"name":32,"role":37,"phone":41,"phoneExt":22,"email":42},"412-677-0575","alterbj@upmc.edu",[44],{"facility":45,"status":46,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"UPMC St. Margaret","RECRUITING","Pittsburgh","Pennsylvania","15215","United States","US",{"type":53,"coordinates":54},"Point",[55,56],-79.99589,40.44062,{"lat":56,"lon":55},[59,60,61],{"name":36,"role":37,"phone":38,"phoneExt":22,"email":39},{"name":32,"role":37,"phone":41,"phoneExt":22,"email":42},{"name":32,"role":33,"phone":22,"phoneExt":22,"email":22},{"type":33,"investigatorFullName":63,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":22,"oldOrganization":22},"Benedict Alter","Assistant Professor","100513156","offset-mechanisms-in-evaluation-of-lumbar-medial-branch-blocks-100513156",false,"NCT05961800","Offset Mechanisms in Evaluation of Lumbar Medial Branch Blocks","OMEGA Study: Offset Mechanisms in Evaluation of Lumbar Medial Branch Block","OMEGA","Inclusion Criteria:\n\n* Scheduled for lumbar MBB in UPMC Pain Management clinics\n* Age \\> 18 years old\n* Predominantly axial chronic low back pain at least 3 months on a daily basis\n* Must meet the minimum criteria for cognitive function using the PROMIS 2-item cognitive screener (\\>3)\n* Low back pain intensity of \\> 3\u002F10\n* Willing and able to receive study-related phone calls\n\nExclusion Criteria:\n\n* History of spine surgery at the level of the lumbar MBB\n* Active worker's compensation or litigation claims\n* New pain and\u002For psychiatric treatments within 2 weeks of enrollment\n* Not fluent in English and\u002For not able to complete the questionnaires\n* Any clinically unstable systemic illness that is judged to interfere with the study","ALL","18 Years",{"count":76,"type":77},40,"ESTIMATED","INTERVENTIONAL",[80],"NA","This study examines the relationship between central nervous system (CNS) mechanisms of pain inhibition and the pain relief that occurs following a lumbar medial branch block (MBB).",[83,84,85,86],"Pain, Chronic","Facet Joint Pain","Pain, Procedural","Analgesia",[88,89,90,91,92,93],"lumbar","medial branch block","offset analgesia","onset hyperalgesia","QST","quantitative sensory testing","2026-06-02",{"date":96,"type":97},"2026-06-04","ACTUAL",{"date":99,"type":97},"2023-07-05",{"date":101,"type":77},"2028-06",{"name":5,"class":6},1]