[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100557406":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":20,"locations":31,"responsibleParty":101,"collaborators":10,"id":103,"slug":104,"hasResults":105,"nctId":106,"briefTitle":107,"officialTitle":108,"acronym":109,"eligibilityCriteria":110,"healthyVolunteers":105,"sex":111,"minAge":112,"maxAge":113,"enrollmentInfo":114,"targetDuration":10,"studyType":117,"phases":10,"briefSummary":118,"conditions":119,"keywords":121,"overallStatus":34,"whyStopped":10,"lastUpdateSubmitDate":127,"lastUpdatePostDateStruct":128,"startDateStruct":131,"completionDateStruct":133,"leadSponsor":135,"locationsCount":136},{"fullName":5,"class":6},"Fondazione Policlinico Universitario Campus Bio-Medico","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Group1 (>=10years) and Group1 (\u003C10years)",null,"Patients will be divided into 2 groups according to their CM history (duration): A) those from 1 to 9 years and B) those with 10 or more years of CM history.",[13],"Drug: OnabotulinumtoxinA OBT-A",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DRUG","OnabotulinumtoxinA OBT-A","Patients will be re-evaluated every 3 months, at each OBT-A cycle, during the whole year of treatment. Every evaluation patients will show their diary of headaches with monthly migraine and headache days and acute medications taken.",[9],[21,27],{"name":22,"role":23,"phone":24,"phoneExt":25,"email":26},"Fabrizio Vernieri, Prof.","CONTACT","003906225411889","Italy","f.vernieri@policlinicocampus.it",{"name":28,"role":23,"phone":29,"phoneExt":25,"email":30},"Claudia Altamura, MD","003906225411270","c.altamura@policlinicocampus.it",[32,47,59,71,80,92],{"facility":33,"status":34,"city":35,"state":10,"zip":10,"country":25,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Università Politecnica delle Marche","RECRUITING","Ancona","IT",{"type":38,"coordinates":39},"Point",[40,41],13.5103,43.60717,{"lat":41,"lon":40},[44],{"name":45,"role":23,"phone":10,"phoneExt":10,"email":46},"Giovanna Viticchi","viticchi.g@gmail.com",{"facility":48,"status":34,"city":49,"state":10,"zip":10,"country":25,"countryCode":36,"cosmosGeoPoint":50,"geoPoint":54,"contacts":55},"Università Studi dell'Aquila","L’Aquila",{"type":38,"coordinates":51},[52,53],13.39954,42.35055,{"lat":53,"lon":52},[56],{"name":57,"role":23,"phone":10,"phoneExt":10,"email":58},"Simona Sacco","simona.sacco@univaq.it",{"facility":60,"status":34,"city":61,"state":10,"zip":10,"country":25,"countryCode":36,"cosmosGeoPoint":62,"geoPoint":66,"contacts":67},"IRCCS Istituto Auxologico Italiano","Milan",{"type":38,"coordinates":63},[64,65],12.59836,42.78235,{"lat":65,"lon":64},[68],{"name":69,"role":23,"phone":10,"phoneExt":10,"email":70},"Alberto Doretti","a.doretti@auxologico.it",{"facility":72,"status":34,"city":61,"state":10,"zip":10,"country":25,"countryCode":36,"cosmosGeoPoint":73,"geoPoint":75,"contacts":76},"Istituto Neurologico Besta",{"type":38,"coordinates":74},[64,65],{"lat":65,"lon":64},[77],{"name":78,"role":23,"phone":10,"phoneExt":10,"email":79},"Licia Grazzi","Licia.Grazzi@istituto-besta.it",{"facility":81,"status":34,"city":82,"state":10,"zip":83,"country":25,"countryCode":36,"cosmosGeoPoint":84,"geoPoint":88,"contacts":89},"Fondazione Policlinico Campus Bio-Medico","Roma","00128",{"type":38,"coordinates":85},[86,87],11.10642,44.99364,{"lat":87,"lon":86},[90],{"name":91,"role":23,"phone":24,"phoneExt":10,"email":26},"Fabrizio Vernieri, Prof",{"facility":93,"status":34,"city":82,"state":10,"zip":10,"country":25,"countryCode":36,"cosmosGeoPoint":94,"geoPoint":96,"contacts":97},"Policlinico Tor Vergata",{"type":38,"coordinates":95},[86,87],{"lat":87,"lon":86},[98],{"name":99,"role":23,"phone":10,"phoneExt":10,"email":100},"Maria Albanese","maria.albanese@hotmail.it",{"type":102,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100557406","onabotulinumtoxin-a-in-chronic-migraine-patients-with-short-or-long-disease-history-the-bach-study-100557406",false,"NCT06537700","OnaBotulinumtoxin-A in Chronic Migraine Patients With Short or Long Disease History (the BACH Study)","OnaBotulinumtoxin-A Effectiveness Evaluation in Chronic Migraine Patients With Short or Long Disease History: an Italian Multicentric Study (the BACH Study)","BACH","Inclusion Criteria:\n\n* Age between 18 and 70 years-old\n* Chronic Migraine defined according to 1.3 ICHD-3\n* Informed consent\n\nExclusion Criteria:\n\n* secondary headache\n* Onabotulinumtoxin-A in the previous 3 months\n* pregnancy or breastfeeding\n* detoxification protocol for Medication Overuse Headache in the last 6 months","ALL","18 Years","70 Years",{"count":115,"type":116},115,"ESTIMATED","OBSERVATIONAL","The goal of this observational prospective multicentric study, 12 months duration is to investigate whether the history of Chronic Migraine and, more precisely, its duration for over or less than 10 years, can predict OBT-A treatment effectiveness.\n\nSince CM patients may have a complex psychopathological profile and psychiatric symptoms represent a bad prognostic factor influencing treatment effectiveness, the present study will also aim at evaluating if the psychopathological profile of the enrolled patients may influence the outcome.",[120],"Migraine",[122,123,124,125,126],"Chronic migraine","OnabotulinumtoxinA","Migraine prevention","Disease duration","Psychiatric comorbidities","2024-09-17",{"date":129,"type":130},"2024-09-19","ACTUAL",{"date":132,"type":130},"2024-01-01",{"date":134,"type":116},"2025-12-31",{"name":5,"class":6},6]