[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100627787":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":20,"locations":26,"responsibleParty":55,"collaborators":19,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":63,"eligibilityCriteria":64,"healthyVolunteers":59,"sex":65,"minAge":66,"maxAge":19,"enrollmentInfo":67,"targetDuration":19,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":76,"overallStatus":78,"whyStopped":19,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Fundacion Arturo Lopez Perez","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Supervised Progressive Resistance Training","EXPERIMENTAL","Participants receive supervised, individualized progressive resistance training twice weekly (60 minutes\u002Fsession) from start of neoadjuvant therapy until surgery (24 weeks).",[13],"Other: Strength training program",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"Strength training program","Individualized supervised progressive resistance training twice weekly (60 minutes\u002Fsession) from start of neoadjuvant therapy to surgery (24 weeks), with loads prescribed from baseline strength testing and progressed every 2 weeks; safety monitored and adapted based on clinical status.",[9],null,[21],{"name":22,"role":23,"phone":24,"phoneExt":19,"email":25},"Nicole M Caire, Medical Oncologist","CONTACT","+56974998222","nicole.caire@falp.org",[27],{"facility":28,"status":19,"city":29,"state":30,"zip":31,"country":32,"countryCode":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"Fundación Arturo López Pérez","Santiago","Santiago Metropolitan","7500921","Chile","CL",{"type":35,"coordinates":36},"Point",[37,38],-70.64827,-33.45694,{"lat":38,"lon":37},[41,45,49,51,53],{"name":42,"role":23,"phone":43,"phoneExt":19,"email":44},"Claudia C Chavez, Master of Science in Biostatis","+56 9 6617 2416","claudia.chavezo@falp.org",{"name":46,"role":23,"phone":47,"phoneExt":19,"email":48},"Macarena B Artigas, kinesiologist","+56990420698","macarena.artigas@falp.org",{"name":22,"role":50,"phone":19,"phoneExt":19,"email":19},"PRINCIPAL_INVESTIGATOR",{"name":46,"role":52,"phone":19,"phoneExt":19,"email":19},"SUB_INVESTIGATOR",{"name":54,"role":50,"phone":19,"phoneExt":19,"email":19},"Gabriel N Marzuca, kinesiologist",{"type":56,"investigatorFullName":19,"investigatorTitle":19,"investigatorAffiliation":19,"oldNameTitle":19,"oldOrganization":19},"SPONSOR","100627787","onco-ret-supervised-resistance-training-during-total-neoadjuvant-therapy-for-locally-advanced-rectal-cancer-100627787",false,"NCT07453173","ONCO-RET: Supervised Resistance Training During Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer","A Pilot, Single-Arm, Prospective Study Assessing Feasibility and Safety of a Supervised Progressive Resistance Training Program During Total NeoadjuvantTherapy (RAPIDO) Until Surgery in Locally Advanced Rectal Cancer","ONCO-RET","Inclusion Criteria:\n\n* Locally advanced rectal adenocarcinoma planned for RAPIDO total neoadjuvant therapy (short-course RT + chemotherapy + surgery), meeting protocol staging criteria (e.g., cT3N1\u002FcT4\u002FcN2\u002FEMVI+\u002Fthreatened mesorectal fascia\u002Flateral pelvic disease).\n\nExclusion Criteria:\n\n* Metastatic disease at diagnosis.\n* Severe\u002Funcontrolled cardiovascular disease (ejection fraction \\<50%).","ALL","18 Years",{"count":68,"type":69},15,"ESTIMATED","INTERVENTIONAL",[72],"NA","Colorectal cancer is a major cause of cancer death in Chile. Many people with rectal cancer that has grown into nearby tissues receive chemotherapy and radiation before surgery. These treatments can cause tiredness and loss of muscle, which may make it harder for patients to complete treatment.\n\nThis study will look at whether a supervised strength-training exercise program is practical and safe during treatment before surgery. Participants will do a personalized strength-training program two times per week. The program will start when cancer treatment begins and will continue until surgery (about 24 weeks).\n\nThe study will measure how practical the program is by looking at how many people join the study, stay in the study, and attend the exercise sessions, and whether the study team can collect all planned information. The study will also track any problems or side effects related to exercise.\n\nThe study will also explore whether the exercise program may help maintain muscle, improve strength and physical function, improve quality of life, reduce fatigue, and affect how the tumor responds to treatment. These results will be compared with information from similar patients previously treated at the same hospital.",[75],"Locally Advanced Rectal Cancer",[77],"prehabilitation; resistance training; total neoadjuvant therapy; RAPIDO; feasibility; safety","NOT_YET_RECRUITING","2026-03-03",{"date":81,"type":82},"2026-03-05","ACTUAL",{"date":84,"type":69},"2026-03-09",{"date":86,"type":69},"2027-03-31",{"name":5,"class":6},1]