[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100549890":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":10,"centralContacts":19,"locations":25,"responsibleParty":39,"collaborators":10,"id":41,"slug":42,"hasResults":43,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":10,"eligibilityCriteria":47,"healthyVolunteers":48,"sex":49,"minAge":50,"maxAge":10,"enrollmentInfo":51,"targetDuration":10,"studyType":54,"phases":10,"briefSummary":55,"conditions":56,"keywords":60,"overallStatus":28,"whyStopped":10,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Oncoliq US Inc","INDUSTRY",[8],{"label":9,"type":10,"description":10,"interventionNames":11},"Women aged 50 to 70 who attend the gynecological annual check-up",null,[12],"Diagnostic Test: Blood sample extraction",[14],{"type":15,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"DIAGNOSTIC_TEST","Blood sample extraction","We do not alter the patient\\'s regular gynecological check-up in any way. The patient will undergo a mammogram and a blood draw. We will then separate a small aliquot of blood for the purposes of the research protocol.",[9],[20],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Javier Stigliano, MD specialist in mastology","CONTACT","+54 9 11 5952-7959","drstigliano@yahoo.com.ar",[26],{"facility":27,"status":28,"city":29,"state":30,"zip":31,"country":32,"countryCode":33,"cosmosGeoPoint":10,"geoPoint":10,"contacts":34},"Hospital Nacional Profesor Alejandro Posadas","RECRUITING","El Palomar, Morón","Buenos Aires","B1684","Argentina","AR",[35,37],{"name":21,"role":22,"phone":36,"phoneExt":10,"email":24},"+549 11 5952 7959",{"name":21,"role":38,"phone":10,"phoneExt":10,"email":10},"PRINCIPAL_INVESTIGATOR",{"type":40,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100549890","oncoliq-early-breast-cancer-detection-based-on-liquid-biopsies-and-micrornas-100549890",false,"NCT06439940","Oncoliq: Early Breast Cancer Detection Based on Liquid Biopsies and microRNAs","Pilot Test for an Early Diagnosis Kit for Breast Cancer Based on Liquid Biopsies","Inclusion Criteria:\n\n* Patients over 35 years old who visit the gynecological clinic for their annual mammographic check-up\n\nExclusion Criteria:\n\n* Personal history of cancer",true,"FEMALE","35 Years",{"count":52,"type":53},364,"ESTIMATED","OBSERVATIONAL","Oncoliq is a novel early breast cancer detection test based on liquid biopsies and microRNAs. This innovative test aims to improve the accuracy of cancer detection, thereby reducing patient mortality and healthcare costs.\n\nTo develop this test, the discovery and validation phases have been completed. In addition, Machine learning and AI were used to determine the algorithm for breast cancer detection.\n\nThe overall objective of this protocol is to implement a pilot test to enroll 1,000 women without a previous cancer diagnosis who are attending their annual medical check-up.\n\nTo achieve this, we will develop the following specific objectives:\n\nEnroll women over age 35 who attend the gynecological annual check-up. Test the plasma of the enrolled volunteers for specific miRNA biomarkers using RT-qPCR.\n\nPerform an analysis based on artificial intelligence techniques in collaboration with IMAGO Systems (USA) on mammogram images.\n\nCompare the results obtained from the clinical check-up (BiRad from mammogram), IMAGO Systems and RT-qPCR (Oncoliq breast test). Conduct a 5-year follow-up on volunteers with pathological results from Oncoliq breast test.\n\nParticipants who meet the inclusion and exclusion criteria and agree to take part in the protocol will be required to sign both pages of the Informed Consent Form and complete the Annex and Survey. Subsequently, a small blood sample of 3-5 mL will be drawn via venipuncture.",[57,58,59],"Breast Cancer Female","Breast Cancer","Breast Carcinoma",[61,62,63,64,65,66,67,68,69,70,71,72,73],"early diagnosis","early detection","cancer","breast cancer","miRNAs","liquid biopsies","pilot study","pilot test","liquid biopsy","Oncoliq","machine learning","AI","RT-qPCR","2024-06-05",{"date":76,"type":77},"2024-06-07","ACTUAL",{"date":79,"type":77},"2021-07-14",{"date":81,"type":53},"2025-03-31",{"name":5,"class":6},1]