[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100483130":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":25,"locations":31,"responsibleParty":50,"collaborators":19,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":59,"sex":60,"minAge":61,"maxAge":19,"enrollmentInfo":62,"targetDuration":19,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":72,"overallStatus":33,"whyStopped":19,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Burke Medical Research Institute","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Spinal reflex conditioning","EXPERIMENTAL","The OC intervention includes 6 baseline sessions and 24 conditioning\u002F no conditioning sessions held 3 times\u002Fweek.\n\nTo elicit an H-reflex, participants will be asked to stand in a comfortable position. Small pulses of energy will be applied to a nerve in the leg called the tibial nerve. We will record when the participant maintains leg muscle activity. During the intervention, participants will be trained to decrease their reflex in their calf.",[13],"Behavioral: Spinal reflex conditioning",[15],{"type":16,"name":9,"description":17,"armGroupLabels":18,"otherNames":19},"BEHAVIORAL","Each participant will serve as their own control. The intervention is 30 sessions. The first 6 sessions are baseline measures of reflexes. The remaining sessions will engage participants in learning how to decrease their reflex activity in their calf muscle on the more-affected leg. Each intervention visit will involve 20 trials in which participants do not get visual feedback about their performance, then 225 trials with visual feedback.",[9],null,[21],{"name":22,"affiliation":23,"role":24},"Kathleen Friel, PhD","Burke Neurological Institute","PRINCIPAL_INVESTIGATOR",[26],{"name":27,"role":28,"phone":29,"phoneExt":19,"email":30},"Devina Kumar, PhD","CONTACT","914-368-3160","dek4004@med.cornell.edu",[32],{"facility":23,"status":33,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"RECRUITING","White Plains","New York","10605","United States","US",{"type":40,"coordinates":41},"Point",[42,43],-73.76291,41.03399,{"lat":43,"lon":42},[46,49],{"name":22,"role":28,"phone":47,"phoneExt":19,"email":48},"914-368-3116","kaf3001@med.cornell.edu",{"name":22,"role":24,"phone":19,"phoneExt":19,"email":19},{"type":51,"investigatorFullName":19,"investigatorTitle":19,"investigatorAffiliation":19,"oldNameTitle":19,"oldOrganization":19},"SPONSOR","100483130","operant-conditioning-of-the-soleus-stretch-reflex-in-adults-with-cerebral-palsy-100483130",false,"NCT05571033","Operant Conditioning of the Soleus Stretch Reflex in Adults With Cerebral Palsy","SRC-CP","Inclusion Criteria:\n\n1. Age 18 and above\n2. Diagnosis of spastic Cerebral Palsy\n3. Gross Motor Function Classification System level I-III\n4. Stable medical background\n5. Current medication will remain unchanged for 3 months\n6. Provides informed consent\n7. can walk at least 10 meters with or without assistive device\n8. meets minimum study procedure requirements (elicitation of H-reflex).\n\nExclusion Criteria:\n\n1. Pregnancy\n2. uncontrolled diabetes\n3. weak dorsiflexion\n4. History of cardiac conditions\n5. cognitive deficits that interfere with study procedure and steps for completion\n6. Botox within 2 months of the study\n7. H\u002FO ankle surgeries in affected leg (Dorsal root rhizotomy etc.)\n8. regular use of electrical stimulation to lower extremity muscles\n9. Cochlear or metal implantations on body\n10. No history of seizure after age 2 years\n11. Current use of antiseizure medicines\n12. Any metal or magnetic components in the head (surgical clips, metal work etc.)\n13. Implanted device or cardiac pacemakers (applicable for DS8R too)\n14. Skin disorders\n15. Damaged skin (wounds, broken skin, or recent scar tissue)\n16. Allergy to latex (tape)",true,"ALL","18 Years",{"count":63,"type":64},12,"ESTIMATED","INTERVENTIONAL",[67],"NA","12 adults with spastic CP will complete 6 baseline sessions and 24 down conditioning sessions held 3 times\u002Fweek. All clinical and physiological assessments collected at baseline will be reassessed after study completion, and follow ups after 2 weeks, 1 month and 3 months. The soleus H reflex (electric analogue of the stretch reflex) will be elicited in all sessions. In each session, participants will complete 20 baseline trials and 225 down conditioning trials to decrease the magnitude of the H-Reflex.",[70,71],"Cerebral Palsy","Spastic Cerebral Palsy",[73,74],"Hoffman Reflex","Spinal Reflex Conditioning","2023-09-25",{"date":77,"type":78},"2023-09-26","ACTUAL",{"date":80,"type":78},"2022-09-30",{"date":82,"type":64},"2026-12-31",{"name":5,"class":6},1]