[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100481520":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":10,"centralContacts":30,"locations":36,"responsibleParty":56,"collaborators":10,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":66,"eligibilityCriteria":67,"healthyVolunteers":62,"sex":68,"minAge":69,"maxAge":10,"enrollmentInfo":70,"targetDuration":73,"studyType":74,"phases":10,"briefSummary":75,"conditions":76,"keywords":81,"overallStatus":39,"whyStopped":10,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Xuanwu Hospital, Beijing","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Optical Coherence Tomography (OCT)",null,"OCT and other classical imaging evaluation such as Transcranial Color Doppler (TCCD) and High resolution-MRI will be performed. The tailored treatment (such as anti-thrombotic management, post-dilation, et al) will be considered when specific plaque characteristics (including but not limited to in situ thrombus formation, macrocacilfication, et al), were observed under OCT.",[13,14],"Diagnostic Test: Optical Coherence Tomography","Procedure: Percutaneous transluminal angioplasty and stenting",{"label":16,"type":10,"description":17,"interventionNames":18},"Non-Optical Coherence Tomography (N-OCT)","Classical imaging evaluation such as TCCD and High resolution-MRI will be performed, followed by standard percutaneous transluminal angioplasty and stenting.",[14],[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":10},"DIAGNOSTIC_TEST","Optical Coherence Tomography","Intravascular evaluation for vessel wall structure of intracranial atherosclerotic stenosis by application of optical coherence tomography",[9],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":10},"PROCEDURE","Percutaneous transluminal angioplasty and stenting","Percutaneous transluminal angioplasty and stenting will be performed follow the standard or adjusted according to OCT evaluation.",[16,9],[31],{"name":32,"role":33,"phone":34,"phoneExt":10,"email":35},"Liqun Jiao, Professor","CONTACT","+8613911224991","liqunjiao@sina.cn",[37],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Xuanwu Hospital, Capital Medical University","RECRUITING","Beijing","Beijing Municipality","100005","China","CN",{"type":46,"coordinates":47},"Point",[48,49],116.39723,39.9075,{"lat":49,"lon":48},[52],{"name":53,"role":33,"phone":54,"phoneExt":10,"email":55},"Ran Xu, MD","+8615001376121","xrqssq@126.com",{"type":57,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","jiaoliqun","Director, Department of Interventional Neuroradiology, Principal Investigator, Clinical Professor","100481520","optical-coherence-tomography-for-intracranial-atherosclerotic-stenosis-100481520",false,"NCT05550077","Optical Coherence Tomography for Intracranial Atherosclerotic Stenosis","Optical Coherence Tomography for Intracranial Atherosclerotic Stenosis: a Prospective Registry Study (OCT-ICAS)","OCT-ICAS","Inclusion Criteria:\n\n* Symptomatic ICAS. Participants with ICAS with a transient ischaemic attack (TIA) or stroke attributable to the territory of the stenotic artery were defined as symptomatic. A TIA was defined as a transient episode of neurological dysfunction (focal weakness or language disturbance, transient monocular blindness, or required assistance in walking) caused by focal brain or retinal ischaemia that lasted for at least 10 minutes but resolved within 24 hours\n* Stenotic degree ≥ 50%, measured by digital subtraction angiography\n* The stenosis must located in at least one major intracranial artery (internal carotid artery, vertebral artery, middle cerebral artery, or basilar artery)\n\nExclusion Criteria:\n\n* Arteriovenous Malformation\n* Aneurysm","ALL","18 Years",{"count":71,"type":72},400,"ESTIMATED","12 Months","OBSERVATIONAL","To evaluate the clinical significance of optical coherence tomography (OCT) in interventional treatment of intracranial atherosclerotic stenosis (ICAS).",[77,22,78,79,80],"Intracranial Atherosclerosis","Plaque, Atherosclerotic","Artery Stenosis","Ischemic Stroke",[22,82,83,84],"Intravascular Imaging","Intracranial Atherosclerotic Stenosis","Percutaneous Transluminal Angioplasty and Stenting","2022-09-21",{"date":87,"type":88},"2022-09-23","ACTUAL",{"date":90,"type":88},"2020-03-15",{"date":92,"type":72},"2027-12-31",{"name":58,"class":6},1]