[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100151502":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":25,"centralContacts":30,"locations":41,"responsibleParty":72,"collaborators":75,"id":79,"slug":80,"hasResults":81,"nctId":82,"briefTitle":83,"officialTitle":83,"acronym":35,"eligibilityCriteria":84,"healthyVolunteers":81,"sex":85,"minAge":86,"maxAge":35,"enrollmentInfo":87,"targetDuration":35,"studyType":90,"phases":91,"briefSummary":93,"conditions":94,"keywords":96,"overallStatus":43,"whyStopped":35,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":110},{"fullName":5,"class":6},"Oregon Health and Science University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Surgery","EXPERIMENTAL","OCT is assisting in surgery guidance.",[13],"Drug: OCT-guided laser phototherapeutic keratectomy",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DRUG","OCT-guided laser phototherapeutic keratectomy","Preoperative measurements from the OCT are used to assist the calculation in deciding the laser depth settings for removal of anterior corneal opacities and defects in the phototherapeutic PTK procedure. The surgeon uses the OCT data to plan a range of treatment parameters to remove most of the opacity while preserving at least 250 microns of residual corneal stroma.",[9],[21,22,23,24],"Manufacturer\u002FName OCT Technology 510(K)","Optovue\u002FRTVue-CAM Fourier-domain K071250","Bioptigen\u002FBioptigen Fourier-domain K063343","Zeiss\u002FVisante Time-domain K051789",[26],{"name":27,"affiliation":28,"role":29},"David Huang, MD, PhD","Casey Eye Institute, Oregon Health & Science University","PRINCIPAL_INVESTIGATOR",[31,37],{"name":32,"role":33,"phone":34,"phoneExt":35,"email":36},"Humberto Martinez, COT","CONTACT","503-494-7712",null,"martinhu@ohsu.edu",{"name":38,"role":33,"phone":39,"phoneExt":35,"email":40},"Denny Romfh, OD","503-494-4351","romfhd@ohsu.edu",[42],{"facility":28,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"RECRUITING","Portland","Oregon","97239","United States","US",{"type":50,"coordinates":51},"Point",[52,53],-122.67621,45.52345,{"lat":53,"lon":52},[56,57,58,59,62,64,66,68,70],{"name":32,"role":33,"phone":34,"phoneExt":35,"email":36},{"name":38,"role":33,"phone":39,"phoneExt":35,"email":40},{"name":27,"role":29,"phone":35,"phoneExt":35,"email":35},{"name":60,"role":61,"phone":35,"phoneExt":35,"email":35},"Winston Chamberlain, MD, PhD","SUB_INVESTIGATOR",{"name":63,"role":61,"phone":35,"phoneExt":35,"email":35},"Afshan Nanji, MD",{"name":65,"role":61,"phone":35,"phoneExt":35,"email":35},"Richard Stutzman, MD",{"name":67,"role":61,"phone":35,"phoneExt":35,"email":35},"Seema Gupta, MD",{"name":69,"role":61,"phone":35,"phoneExt":35,"email":35},"Ellen Davis, MD",{"name":71,"role":61,"phone":35,"phoneExt":35,"email":35},"Yan Li, PhD",{"type":29,"investigatorFullName":73,"investigatorTitle":74,"investigatorAffiliation":5,"oldNameTitle":35,"oldOrganization":35},"David Huang",": David Huang, MD, PhD, Professor of Ophthalmology",[76],{"name":77,"class":78},"National Eye Institute (NEI)","NIH","100151502","optical-coherence-tomography-guided-transepithelial-phototherapeutic-keratectomy-100151502",false,"NCT01243931","Optical Coherence Tomography Guided Transepithelial Phototherapeutic Keratectomy","Inclusion Criteria:\n\n* Patients with vision primarily limited by superficial opacities and irregularities that could be removed by PTK while leaving at least 250 µm.\n\nExclusion Criteria:\n\n* Inability to give informed consent\n* Inability to maintain stable fixation for OCT imaging\n* Inability to commit to required visits to complete the study\n* Deep corneal opacities and irregularities\n* Cataracts, retinal disease, glaucoma, or other eye conditions that may limit the visual outcome after surgery","ALL","18 Years",{"count":88,"type":89},80,"ESTIMATED","INTERVENTIONAL",[92],"NA","Optical Coherence Tomography (OCT) machines are non-contact instruments that can measure the depth of scars and other causes of cloudiness in the front of the cornea. The purpose of this study is to determine whether OCT-guided settings for the lasers used for removal of corneal scars and other partial-thickness corneal defects result in improved vision in patients receiving these procedures.",[95],"Corneal Opacity",[97,98,99,100],"Phototherapeutic keratectomy","Optical coherence tomography","Corneal opacity","Corneal dystrophy","2024-02-08",{"date":103,"type":104},"2024-02-12","ACTUAL",{"date":106,"type":35},"2011-06",{"date":108,"type":89},"2026-12",{"name":5,"class":6},1]