[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100635695":3},{"organization":4,"armGroups":7,"interventions":32,"overallOfficials":38,"centralContacts":43,"locations":52,"responsibleParty":69,"collaborators":11,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":78,"sex":79,"minAge":80,"maxAge":81,"enrollmentInfo":82,"targetDuration":11,"studyType":85,"phases":86,"briefSummary":88,"conditions":89,"keywords":11,"overallStatus":91,"whyStopped":11,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Maastricht University Medical Center","OTHER",[8,14,17,20,23,26,29],{"label":9,"type":10,"description":11,"interventionNames":12},"0.4 g protein･kg BM-1･d-1","EXPERIMENTAL",null,[13],"Dietary Supplement: Amino Acid",{"label":15,"type":10,"description":11,"interventionNames":16},"0.6 g protein･kg BM-1･d-1",[13],{"label":18,"type":10,"description":11,"interventionNames":19},"0.8 g protein･kg BM-1･d-1",[13],{"label":21,"type":10,"description":11,"interventionNames":22},"1.0 g protein･kg BM-1･d-1",[13],{"label":24,"type":10,"description":11,"interventionNames":25},"1.2 g protein･kg BM-1･d-1",[13],{"label":27,"type":10,"description":11,"interventionNames":28},"1.5 g protein･kg BM-1･d-1",[13],{"label":30,"type":10,"description":11,"interventionNames":31},"1.8 g protein･kg BM-1･d-1",[13],[33],{"type":34,"name":35,"description":36,"armGroupLabels":37,"otherNames":11},"DIETARY_SUPPLEMENT","Amino Acid","Test diet consisting of free amino acid mixtures based on milk protein.",[9,15,18,21,24,27,30],[39],{"name":40,"affiliation":41,"role":42},"Luc JC van Loon, PhD","Maastricht University","PRINCIPAL_INVESTIGATOR",[44,49],{"name":45,"role":46,"phone":47,"phoneExt":11,"email":48},"Julia M Malowany, MSc","CONTACT","+31 43 388 1617","julia.malowany@maastrichtuniversity.nl",{"name":50,"role":46,"phone":47,"phoneExt":11,"email":51},"Jorn Trommelen, PhD","jorn.trommelen@maastrichtuniversity.nl",[53],{"facility":54,"status":11,"city":55,"state":56,"zip":57,"country":58,"countryCode":59,"cosmosGeoPoint":60,"geoPoint":65,"contacts":66},"Maastricht University Medical Centre+","Maastricht","Limburg","6200 MD","Netherlands","NL",{"type":61,"coordinates":62},"Point",[63,64],5.68889,50.84833,{"lat":64,"lon":63},[67],{"name":45,"role":46,"phone":47,"phoneExt":11,"email":68},"julia.malowany@mastrichtuniversity.nl",{"type":70,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100635695","optimal-protein-intake-to-maximize-whole-body-protein-balance-in-healthy-adults-100635695",false,"NCT07556029","Optimal Protein Intake to Maximize Whole-Body Protein Balance in Healthy Adults","PAAKO","Inclusion Criteria:\n\n* Aged between 18-35 years\n* BMI between 18.5-30 kg\u002Fm2\n* Healthy, recreationally active (exercise at least once per two weeks and a maximum of four days per week)\n* No physical limitations (i.e., able to perform all activities associated with daily living independently)\n\nExclusion Criteria:\n\n* Smoking\n* Diagnosed musculoskeletal disorders\n* Use of any medications known to affect protein metabolism (i.e., corticosteroids, non-steroidal anti-inflammatories, or prescribed acne medications)\n* Chronic use of gastric acid-suppressing medication or anti-coagulants\n* Unstable weight over the last three months\n* Diagnosed GI tract disorders or diseases\n* Blood donation in the past 2 months\n* Females: pregnancy",true,"ALL","18 Years","35 Years",{"count":83,"type":84},12,"ESTIMATED","INTERVENTIONAL",[87],"NA","The purpose of this study is to assess the optimal protein intake to maximize whole-body protein net balance in healthy adults. In a randomized, double-blinded, crossover design, 12 young, healthy adult males and females aged 18-35 years, will consume a test diet consisting of free amino acid mixtures based on milk protein that vary in protein content 7 separate acute metabolic trials. The main study endpoint is optimal protein intake based on the lowest protein intake that maximizes whole-body protein net balance.",[90],"Protein Metabolism","NOT_YET_RECRUITING","2026-04-21",{"date":94,"type":95},"2026-04-29","ACTUAL",{"date":97,"type":84},"2026-08-01",{"date":99,"type":84},"2027-04-01",{"name":5,"class":6},1]