[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100559220":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":23,"centralContacts":28,"locations":33,"responsibleParty":53,"collaborators":12,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":12,"eligibilityCriteria":62,"healthyVolunteers":58,"sex":63,"minAge":64,"maxAge":12,"enrollmentInfo":65,"targetDuration":12,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":75,"overallStatus":35,"whyStopped":12,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Rush University Medical Center","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Early morning timing of spontaneous breathing trial","NO_INTERVENTION","Early Morning Group: Patients in this group will undergo their SBTs between 4:00 AM and 5:00 AM, following the traditional early morning schedule used in some ICUs.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Later morning timing of spontaneous breathing trial","EXPERIMENTAL","Later Morning Group: Patients in this group will have their SBTs scheduled between 8:00 AM and 9:00 AM, closer to the time of day shift rounds.",[18],"Other: Later Morning Timing of Spontaneous Breathing Trials",[20],{"type":6,"name":21,"description":16,"armGroupLabels":22,"otherNames":12},"Later Morning Timing of Spontaneous Breathing Trials",[14],[24],{"name":25,"affiliation":26,"role":27},"JIE LI, PhD","Rush University","PRINCIPAL_INVESTIGATOR",[29],{"name":25,"role":30,"phone":31,"phoneExt":12,"email":32},"CONTACT","3125634643","jie_li@rush.edu",[34],{"facility":5,"status":35,"city":36,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"RECRUITING","Chicago","Illinois","60612","United States","US",{"type":42,"coordinates":43},"Point",[44,45],-87.65005,41.85003,{"lat":45,"lon":44},[48,50],{"name":49,"role":30,"phone":31,"phoneExt":12,"email":32},"Jie Li, PhD",{"name":51,"role":52,"phone":12,"phoneExt":12,"email":12},"Lingyue Gong, MS","SUB_INVESTIGATOR",{"type":27,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"Jie Li","Professor","100559220","optimal-timing-for-spontaneous-breathing-trials-100559220",false,"NCT06561295","Optimal Timing for Spontaneous Breathing Trials","Impact of Spontaneous Breathing Trial Timing on Outcomes in Mechanically Ventilated Adult Patients","Inclusion Criteria:\n\n* Adults aged 21 years or older.\n* Patients who have been on mechanical ventilation for more than 48 hours.\n* Patients who have completed at least one SBT.\n\nExclusion Criteria:\n\n* Patients intubated at other hospitals.\n* Patients intubated for surgical or interventional procedures.\n* Patients receiving venovenous extracorporeal membrane oxygenation (VV-ECMO).\n* Patients with a tracheostomy.","ALL","21 Years",{"count":66,"type":67},348,"ESTIMATED","INTERVENTIONAL",[70],"NA","This study aims to explore how the timing of Spontaneous Breathing Trials (SBTs) affects recovery in adult patients who are on mechanical ventilation in the ICU. SBTs are tests used to determine if a patient is ready to breathe on their own without the help of a ventilator. The study will compare two different timing strategies for these trials: one group of patients will have the test early in the morning, while the other group will have it later in the morning. By observing the outcomes, such as how long patients need to stay on the ventilator, the study hopes to find the best time to perform these trials to help patients recover more quickly and safely.",[73,74],"Respiration, Artificial","Weaning",[76,74,77],"Spontaneous breathing trial","Mechanical ventilation duration","2025-09-26",{"date":80,"type":81},"2025-09-30","ACTUAL",{"date":83,"type":81},"2024-09-17",{"date":85,"type":67},"2026-12-30",{"name":5,"class":6},1]