[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100480700":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":41,"centralContacts":46,"locations":52,"responsibleParty":336,"collaborators":27,"id":338,"slug":339,"hasResults":340,"nctId":341,"briefTitle":342,"officialTitle":343,"acronym":344,"eligibilityCriteria":345,"healthyVolunteers":340,"sex":346,"minAge":347,"maxAge":27,"enrollmentInfo":348,"targetDuration":27,"studyType":351,"phases":352,"briefSummary":354,"conditions":355,"keywords":359,"overallStatus":55,"whyStopped":27,"lastUpdateSubmitDate":367,"lastUpdatePostDateStruct":368,"startDateStruct":371,"completionDateStruct":373,"leadSponsor":375,"locationsCount":376},{"fullName":5,"class":6},"University Hospital, Bordeaux","OTHER",[8,16],{"label":9,"type":10,"description":11,"interventionNames":12},"Treatment group","EXPERIMENTAL","Combination rapid sequence intubation (RSI) with use of rocuronium and the bag-mask ventilation between induction and Gum Elastic Bougie GEB will be systematically used at the first attempt to facilitate intubation.",[13,14,15],"Other: Data patient","Other: Physical examination","Procedure: Rapid sequence intubation (RSI) : Rocuronium \u002FBag-mask ventilation \u002FGEB",{"label":17,"type":18,"description":19,"interventionNames":20},"Control Group","ACTIVE_COMPARATOR","Physicians will be reminded of the current recommendations for emergency intubation: Rapid sequence intubation (RSI) using succinylcholine and use of GEB to facilitate intubation in case of intubation failure under direct laryngoscopy.",[13,14,21],"Procedure: Rapid sequence intubation (RSI) : Recommendations for emergency intubation",[23,28,32,37],{"type":6,"name":24,"description":25,"armGroupLabels":26,"otherNames":27},"Data patient","Medical History and characteristic of patient",[17,9],null,{"type":6,"name":29,"description":30,"armGroupLabels":31,"otherNames":27},"Physical examination","Arterial pressure, arterial oxygen saturation, heart rate",[17,9],{"type":33,"name":34,"description":35,"armGroupLabels":36,"otherNames":27},"PROCEDURE","Rapid sequence intubation (RSI) : Rocuronium \u002FBag-mask ventilation \u002FGEB","Rapid sequence intubation (RSI) will be performed with use of rocuronium as paralytic agent (1.2 mg\u002F kg). Bag-mask ventilation between induction and laryngoscopy will be performed. The GEB will be systematically used at the first attempt to facilitate intubation.",[9],{"type":33,"name":38,"description":39,"armGroupLabels":40,"otherNames":27},"Rapid sequence intubation (RSI) : Recommendations for emergency intubation","Rapid sequence intubation (RSI) using succinylcholine as a paralytic agent (1 mg\u002Fkg), no systematic bag-mask ventilation between induction and laryngoscopy, use of GEB to facilitate intubation in case of intubation failure under direct laryngoscopy.",[17],[42],{"name":43,"affiliation":44,"role":45},"Xavier COMBES, Pr","Université Hospital, Bordeaux","PRINCIPAL_INVESTIGATOR",[47],{"name":43,"role":48,"phone":49,"phoneExt":50,"email":51},"CONTACT","05 56 79 49 47","033","xavier.combes@chu-bordeaux.fr",[53,70,83,96,109,121,134,148,161,174,187,200,213,226,239,252,265,274,284,297,310,323],{"facility":54,"status":55,"city":56,"state":27,"zip":57,"country":58,"countryCode":59,"cosmosGeoPoint":60,"geoPoint":65,"contacts":66},"CHU d'Angers","RECRUITING","Angers","49933","France","FR",{"type":61,"coordinates":62},"Point",[63,64],-0.55202,47.47156,{"lat":64,"lon":63},[67],{"name":68,"role":48,"phone":27,"phoneExt":27,"email":69},"Dominique SAVARY","dominique.savary@chu-angers.fr",{"facility":71,"status":55,"city":72,"state":27,"zip":73,"country":58,"countryCode":59,"cosmosGeoPoint":74,"geoPoint":78,"contacts":79},"CH Carnelle Portes de l'Oise","Beaumont-sur-Oise","95260",{"type":61,"coordinates":75},[76,77],2.28705,49.14232,{"lat":77,"lon":76},[80],{"name":81,"role":48,"phone":27,"phoneExt":27,"email":82},"Agnès Agnès RICARD-HIBON","agnes.ricard-hibon@ght-novo.fr",{"facility":84,"status":55,"city":85,"state":27,"zip":86,"country":58,"countryCode":59,"cosmosGeoPoint":87,"geoPoint":91,"contacts":92},"AP-HP - Hôpital Avicenne","Bobigny","93000",{"type":61,"coordinates":88},[89,90],2.45012,48.90982,{"lat":90,"lon":89},[93],{"name":94,"role":48,"phone":27,"phoneExt":27,"email":95},"Frédéric LAPOSTOLLE","frederic.lapostolle@aphp.fr",{"facility":97,"status":55,"city":98,"state":27,"zip":99,"country":58,"countryCode":59,"cosmosGeoPoint":100,"geoPoint":104,"contacts":105},"CHU de Bordeaux - Hôpital Pellegrin","Bordeaux","33000",{"type":61,"coordinates":101},[102,103],-0.58046,44.84124,{"lat":103,"lon":102},[106,107],{"name":43,"role":48,"phone":27,"phoneExt":27,"email":51},{"name":108,"role":45,"phone":27,"phoneExt":27,"email":27},"Xavier COMBES, PR",{"facility":110,"status":55,"city":111,"state":27,"zip":112,"country":58,"countryCode":59,"cosmosGeoPoint":113,"geoPoint":117,"contacts":118},"CH de Pontoise René Dubos","Cergy-Pontoise","95303",{"type":61,"coordinates":114},[115,116],2.07805,49.03894,{"lat":116,"lon":115},[119],{"name":120,"role":48,"phone":27,"phoneExt":27,"email":82},"Agnès RICARD-HIBON",{"facility":122,"status":55,"city":123,"state":27,"zip":124,"country":58,"countryCode":59,"cosmosGeoPoint":125,"geoPoint":129,"contacts":130},"AP-HP - Hôpital Henri Mondor","Créteil","94000",{"type":61,"coordinates":126},[127,128],2.46569,48.79266,{"lat":128,"lon":127},[131],{"name":132,"role":48,"phone":27,"phoneExt":27,"email":133},"Charlotte CHOLLET-XEMARD","charlotte.chollet@aphp.fr",{"facility":135,"status":136,"city":137,"state":27,"zip":138,"country":58,"countryCode":59,"cosmosGeoPoint":139,"geoPoint":143,"contacts":144},"CHU de Dijon","NOT_YET_RECRUITING","Dijon","21000",{"type":61,"coordinates":140},[141,142],5.01391,47.31344,{"lat":142,"lon":141},[145],{"name":146,"role":48,"phone":27,"phoneExt":27,"email":147},"Patrick RAY","patrick.ray@chu-dijon.fr",{"facility":149,"status":55,"city":150,"state":27,"zip":151,"country":58,"countryCode":59,"cosmosGeoPoint":152,"geoPoint":156,"contacts":157},"GH Eaubonne Montmorency Hôpital Simone VEIL","Eaubonne","95600",{"type":61,"coordinates":153},[154,155],2.28249,48.99712,{"lat":155,"lon":154},[158],{"name":159,"role":48,"phone":27,"phoneExt":27,"email":160},"Laure GUILLOUX","laure.guilloux@hotmail.fr",{"facility":162,"status":55,"city":163,"state":27,"zip":164,"country":58,"countryCode":59,"cosmosGeoPoint":165,"geoPoint":169,"contacts":170},"AP-HP - Hôpital Raymond Poincaré","Garches","92380",{"type":61,"coordinates":166},[167,168],2.18232,48.84226,{"lat":168,"lon":167},[171],{"name":172,"role":48,"phone":27,"phoneExt":27,"email":173},"Armelle SEVERIN","armelle.severin@aphp.fr",{"facility":175,"status":55,"city":176,"state":27,"zip":177,"country":58,"countryCode":59,"cosmosGeoPoint":178,"geoPoint":182,"contacts":183},"CHU de Grenoble - Hôpital Nord La Tronche","La Tronche","38700",{"type":61,"coordinates":179},[180,181],5.74629,45.20507,{"lat":181,"lon":180},[184],{"name":185,"role":48,"phone":27,"phoneExt":27,"email":186},"Guillaume DEBATY","gdebaty@chu-grenoble.fr",{"facility":188,"status":136,"city":189,"state":27,"zip":190,"country":58,"countryCode":59,"cosmosGeoPoint":191,"geoPoint":195,"contacts":196},"CH de Versailles - Site André Mignot","Le Chesnay","78157",{"type":61,"coordinates":192},[193,194],2.12213,48.8222,{"lat":194,"lon":193},[197],{"name":198,"role":48,"phone":27,"phoneExt":27,"email":199},"Clotilde CAZENAVE","ccazenave@ght78sud.fr",{"facility":201,"status":55,"city":202,"state":27,"zip":203,"country":58,"countryCode":59,"cosmosGeoPoint":204,"geoPoint":208,"contacts":209},"HCL - Hôpital Edouard Herriot","Lyon","69003",{"type":61,"coordinates":205},[206,207],4.84789,45.74906,{"lat":207,"lon":206},[210],{"name":211,"role":48,"phone":27,"phoneExt":27,"email":212},"Marine PAUPE","marine.paupe@chu-lyon.fr",{"facility":214,"status":55,"city":215,"state":27,"zip":216,"country":58,"countryCode":59,"cosmosGeoPoint":217,"geoPoint":221,"contacts":222},"GH Sud Ile de France","Melun","77000",{"type":61,"coordinates":218},[219,220],2.65356,48.5457,{"lat":220,"lon":219},[223],{"name":224,"role":48,"phone":27,"phoneExt":27,"email":225},"Yousra GUETARI","yousra.guetari@ghsif.fr",{"facility":227,"status":55,"city":228,"state":27,"zip":229,"country":58,"countryCode":59,"cosmosGeoPoint":230,"geoPoint":234,"contacts":235},"CHU de Montpellier Site Lapeyronie","Montpellier","34000",{"type":61,"coordinates":231},[232,233],3.87635,43.61093,{"lat":233,"lon":232},[236],{"name":237,"role":48,"phone":27,"phoneExt":27,"email":238},"Xavier BOBBIA","xavier.bobbia@chu-montpellier.fr",{"facility":240,"status":55,"city":241,"state":27,"zip":242,"country":58,"countryCode":59,"cosmosGeoPoint":243,"geoPoint":247,"contacts":248},"CHU de Nantes - Hôpital Hôtel Dieu","Nantes","44093",{"type":61,"coordinates":244},[245,246],-1.55336,47.21725,{"lat":246,"lon":245},[249],{"name":250,"role":48,"phone":27,"phoneExt":27,"email":251},"Quentin LE BASTARD","quentin.lebastard@chu-nantes.fr",{"facility":253,"status":55,"city":254,"state":27,"zip":255,"country":58,"countryCode":59,"cosmosGeoPoint":256,"geoPoint":260,"contacts":261},"AP-HP - Hôpital Lariboisière","Paris","75013",{"type":61,"coordinates":257},[258,259],2.3488,48.85341,{"lat":259,"lon":258},[262],{"name":263,"role":48,"phone":27,"phoneExt":27,"email":264},"Xavier EYER","xavier.eyer@aphp.fr",{"facility":266,"status":55,"city":254,"state":27,"zip":255,"country":58,"countryCode":59,"cosmosGeoPoint":267,"geoPoint":269,"contacts":270},"AP-HP - Hôpital Pitié-Salpétrière",{"type":61,"coordinates":268},[258,259],{"lat":259,"lon":258},[271],{"name":272,"role":48,"phone":27,"phoneExt":27,"email":273},"Patrick ECOLLAN","patrick.ecollan@aphp.fr",{"facility":275,"status":55,"city":254,"state":27,"zip":276,"country":58,"countryCode":59,"cosmosGeoPoint":277,"geoPoint":279,"contacts":280},"AP-HP - Hôpital Necker","75730",{"type":61,"coordinates":278},[258,259],{"lat":259,"lon":258},[281],{"name":282,"role":48,"phone":27,"phoneExt":27,"email":283},"Thomas NICOL","thomas.nicol@aphp.fr",{"facility":285,"status":55,"city":286,"state":27,"zip":287,"country":58,"countryCode":59,"cosmosGeoPoint":288,"geoPoint":292,"contacts":293},"CHU Poitiers - Hôpital la Milétrie","Poitiers","86021",{"type":61,"coordinates":289},[290,291],0.34348,46.58261,{"lat":291,"lon":290},[294],{"name":295,"role":48,"phone":27,"phoneExt":27,"email":296},"Nicolas MARJANOVIC","nicolas.marjanovic@chu-poitiers.fr",{"facility":298,"status":55,"city":299,"state":27,"zip":300,"country":58,"countryCode":59,"cosmosGeoPoint":301,"geoPoint":305,"contacts":306},"CHU de la Réunion - site Sud","Saint-Pierre","97448",{"type":61,"coordinates":302},[303,304],5.40682,43.29282,{"lat":304,"lon":303},[307],{"name":308,"role":48,"phone":27,"phoneExt":27,"email":309},"Adrien MARTEAU","adrien.marteau@chu-reunion.fr",{"facility":311,"status":136,"city":312,"state":27,"zip":313,"country":58,"countryCode":59,"cosmosGeoPoint":314,"geoPoint":318,"contacts":319},"GH Sélestat Obernai","Sélestat","67 600",{"type":61,"coordinates":315},[316,317],7.4489,48.26195,{"lat":317,"lon":316},[320],{"name":321,"role":48,"phone":27,"phoneExt":27,"email":322},"Gautier DROMSON","gautier.dromson@ghso.fr",{"facility":324,"status":55,"city":325,"state":27,"zip":326,"country":58,"countryCode":59,"cosmosGeoPoint":327,"geoPoint":331,"contacts":332},"CHU Toulouse - Hôpital Purpan","Toulouse","31059",{"type":61,"coordinates":328},[329,330],1.44367,43.60426,{"lat":330,"lon":329},[333],{"name":334,"role":48,"phone":27,"phoneExt":27,"email":335},"Bertrand GUIHARD","guihard.b@chu-toulouse.fr",{"type":337,"investigatorFullName":27,"investigatorTitle":27,"investigatorAffiliation":27,"oldNameTitle":27,"oldOrganization":27},"SPONSOR","100480700","optimisation-strategy-for-emergency-tracheal-intubation-100480700",false,"NCT05539391","Optimisation Strategy for Emergency Tracheal Intubation","Effectiveness of an Optimisation Strategy for Emergency Tracheal Intubation on Postintubation Morbidity: A Cluster Randomized Controlled Trial","OSETIM","Inclusion Criteria:\n\n* Patient adult (≥ 18 years) presenting with vital distress requiring emergency tracheal intubation as assessed by the emergency physician in the out-of-hospital setting.\n* Patient with all conditions (trauma, dyspnea, coma, overdoses, and shock) except those in cardiac arrest will be included.\n\nExclusion Criteria:\n\n* Patient presenting of a contraindication to succinylcholine, and\u002For rocuronium, and\u002For sugammadex (rocunorium antagonist).\n* Patient who have contraindication to bag face mask ventilation before intubation (ongoing emesis, hematemesis, or hemoptysis).\n* Patient that are not members of a medical aid scheme (beneficiary or main member).\n* Patient under specific protection measures: pregnant, parturient or nursing women; legal protection or deprived of liberty: patient under judicial protection, patient under guardianship\u002Fcuratorship.","ALL","18 Years",{"count":349,"type":350},1500,"ESTIMATED","INTERVENTIONAL",[353],"NA","This study has to objective to assess, in adults' patients needing tracheal intubation because of vital distress, the effect of a combined strategy to reduce intubation-related morbidity. This strategy will associate systematic use of rocuronium as paralyzing agent to facilitate tracheal intubation, bag face-mask ventilation before intubation and Gum Elastic Bougie (GEB) use.",[356,357,358],"Emergencies","Out-of-hospital Setting","Tracheal Intubation",[360,361,362,363,364,365,366],"Out-of-hospital","Intubation","Complications","Vital distress","Rapid sequence intubation","Rocuronium","Gum Elastic Bougie","2025-09-23",{"date":369,"type":370},"2025-09-24","ACTUAL",{"date":372,"type":370},"2023-01-14",{"date":374,"type":350},"2026-09",{"name":5,"class":6},22]