[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100505740":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":32,"locations":41,"responsibleParty":60,"collaborators":11,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":70,"eligibilityCriteria":71,"healthyVolunteers":66,"sex":72,"minAge":73,"maxAge":11,"enrollmentInfo":74,"targetDuration":11,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":85,"overallStatus":44,"whyStopped":11,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"University Hospital, Geneva","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Interventional group","EXPERIMENTAL",null,[13],"Other: Optimisation of nutrition therapy coupled with early mobilisation",{"label":15,"type":16,"description":11,"interventionNames":17},"Control group","ACTIVE_COMPARATOR",[18],"Other: Standard care",[20,24],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":11},"Optimisation of nutrition therapy coupled with early mobilisation","Optimisation of nutrition therapy coupled with early mobilisation with:\n\n* Optimisation of nutrition therapy during ICU stay\n* Optimisation of physiotherapy during ICU stay\n* Better communication and closer collaboration between physiotherapy and nutrition teams.\n* Optimisation of continuity of the care.",[9],{"type":6,"name":25,"description":26,"armGroupLabels":27,"otherNames":11},"Standard care","Patients will receive nutritional therapy and mobilisation according to local standard procedures.",[15],[29],{"name":30,"affiliation":5,"role":31},"Claudia Heidegger, MD","PRINCIPAL_INVESTIGATOR",[33,37],{"name":30,"role":34,"phone":35,"phoneExt":11,"email":36},"CONTACT","+ 41 22 37 27 440","claudia.heidegger@hcuge.ch",{"name":38,"role":34,"phone":39,"phoneExt":11,"email":40},"Aude de Watteville, Bsc","+ 41 79 55 33 998","aude.dewatteville@hcuge.ch",[42],{"facility":43,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Service of Intensive Care, Geneva University Hospital,","RECRUITING","Geneva","Canton of Geneva","1211","Switzerland","CH",{"type":51,"coordinates":52},"Point",[53,54],6.14569,46.20222,{"lat":54,"lon":53},[57,58],{"name":30,"role":34,"phone":11,"phoneExt":11,"email":36},{"name":59,"role":34,"phone":11,"phoneExt":11,"email":40},"Aude De Watteville, Bsc",{"type":61,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"SPONSOR_INVESTIGATOR","HEIDEGGER CP","Deputy head physician, Head of the Intensive Care Polyvalent Unit, Division of Intensive Care","100505740","optimised-nutritional-therapy-and-early-physiotherapy-in-long-term-icu-patients-nutriphyt-trial-100505740",false,"NCT05865314","Optimised Nutritional Therapy and Early Physiotherapy in Long Term ICU Patients (NutriPhyT Trial)","Optimised Nutritional Therapy and Early Physiotherapy in Long Term ICU Patients: a Randomized Controlled Study (NutriPhyT Trial)","NutriPhyT","Inclusion Criteria:\n\nAny patient admitted to the adult ICU :\n\n* ≥18 years old\n* On mechanical ventilation with an expected length of stay ≥ 7 days\n* Requiring artificial nutrition (enteral and\u002For parenteral nutrition)\n\nExclusion Criteria:\n\nTherapeutic withdrawal Pregnant or breastfeeding patients\n\nNeurological disorders with motor deficits:\n\n* New or pre-existing neuromuscular or nervous system disease\n* Spinal cord injury Severe polytrauma of the lower limbs (amputation etc.) Non-independent ambulation (including walking aids) before ICU admission\n\nFor organizational reasons not allowing follow-up :\n\n* Transfer to another ICU\n* Patient living abroad from Switzerland\n* Patient living in nursing homes preceding to ICU admission\n* Incarcerated patients\n* Intellectual\u002Fcognitive disabilities or language barrier, limiting ability to follow the instructions","ALL","18 Years",{"count":75,"type":76},164,"ESTIMATED","INTERVENTIONAL",[79],"NA","Due to medical advances and quality of care, mortality in adult intensive care units (ICUs) has decreased significantly in recent years, leading to a significant increase in the number of patients with high rehabilitation needs on discharge from the ICU.\n\nA specific management by a multidisciplinary team has been set up since 2017 at the Geneva-ICU for long-stay patients (hospitalised ≥ 7 days).\n\nThis study aim to assess whether an optimization of the nutritional therapy coupled with an early mobility during and after the ICU stay allows an improvement in the muscle function at hospital discharge compared to patients receiving the standard care.",[82,83,84],"Critical Illness","ICU Acquired Weakness","Malnutrition",[86,87,88,89],"Early nutrition therapy","Early mobilisation","Long stay ICU patient","Physiotherapy","2025-08-07",{"date":92,"type":93},"2025-08-12","ACTUAL",{"date":95,"type":93},"2023-05-01",{"date":97,"type":76},"2026-09-01",{"name":62,"class":6},1]