[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100487585":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":43,"locations":49,"responsibleParty":87,"collaborators":10,"id":89,"slug":90,"hasResults":91,"nctId":92,"briefTitle":93,"officialTitle":94,"acronym":95,"eligibilityCriteria":96,"healthyVolunteers":97,"sex":98,"minAge":99,"maxAge":10,"enrollmentInfo":100,"targetDuration":10,"studyType":103,"phases":10,"briefSummary":104,"conditions":105,"keywords":107,"overallStatus":52,"whyStopped":10,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":122},{"fullName":5,"class":6},"Peking Union Medical College Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Carotid artery stenosis",null,"patient with carotid artery stenosis",[13,14,15,16,17],"Procedure: Carotid revascularization","Diagnostic Test: MRI-PWI","Diagnostic Test: CTA","Diagnostic Test: PET\u002FMRI","Diagnostic Test: Ultrasound",[19,26,31,35,39],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"PROCEDURE","Carotid revascularization","All patients received carotid revascularization surgery at Peking Union Medical College Hospital.",[9],[25],"carotid endarterectomy and carotid artery stent",{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":10},"DIAGNOSTIC_TEST","MRI-PWI","Multi-modal MRI before and after surgery.",[9],{"type":27,"name":32,"description":33,"armGroupLabels":34,"otherNames":10},"CTA","CTA before and after surgery.",[9],{"type":27,"name":36,"description":37,"armGroupLabels":38,"otherNames":10},"PET\u002FMRI","PET\u002FMRI before surgery.",[9],{"type":27,"name":40,"description":41,"armGroupLabels":42,"otherNames":10},"Ultrasound","Ultrasound before and after surgery.",[9],[44],{"name":45,"role":46,"phone":47,"phoneExt":10,"email":48},"Zhichao Lai, MD","CONTACT","01069152500","zhichao_lai@126.com",[50],{"facility":51,"status":52,"city":53,"state":54,"zip":55,"country":56,"countryCode":57,"cosmosGeoPoint":58,"geoPoint":63,"contacts":64},"vascular surgery department of PUMCH","RECRUITING","Beijing","Beijing Municipality","100730","China","CN",{"type":59,"coordinates":60},"Point",[61,62],116.39723,39.9075,{"lat":62,"lon":61},[65,66,69,71,72,74,76,79,81,83,85],{"name":45,"role":46,"phone":47,"phoneExt":10,"email":48},{"name":67,"role":68,"phone":10,"phoneExt":10,"email":10},"Bao Liu, MD","PRINCIPAL_INVESTIGATOR",{"name":70,"role":68,"phone":10,"phoneExt":10,"email":10},"Changwei Liu, MD",{"name":45,"role":68,"phone":10,"phoneExt":10,"email":10},{"name":73,"role":68,"phone":10,"phoneExt":10,"email":10},"Feng Feng, MD",{"name":75,"role":68,"phone":10,"phoneExt":10,"email":10},"Li Huo, MD",{"name":77,"role":78,"phone":10,"phoneExt":10,"email":10},"Meiqi Wu, MD","SUB_INVESTIGATOR",{"name":80,"role":78,"phone":10,"phoneExt":10,"email":10},"Xiaoyuan Fan, MD",{"name":82,"role":78,"phone":10,"phoneExt":10,"email":10},"Ying Wang, MD",{"name":84,"role":78,"phone":10,"phoneExt":10,"email":10},"Li Zhang, MD",{"name":86,"role":78,"phone":10,"phoneExt":10,"email":10},"Liangrui Zhou, MD",{"type":88,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100487585","optimization-strategy-of-carotid-artery-stenosis-100487585",false,"NCT05629000","Optimization Strategy of Carotid Artery Stenosis","Cohort of Optimized Assessment Strategy of Carotid Artery Stenosis","COAS-CAS","Inclusion Criteria:\n\n1. patients with severe stenosis (≥50%) or near-occlusion diagnosed by computed tomographic angiogram;\n2. patients received carotid endarterectomy at Peking Union Medical College Hospital\n\nExclusion Criteria:\n\n(1) Any contraindication to image examination; (3) refuse to sign the Informed consent.",true,"ALL","18 Years",{"count":101,"type":102},1000,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to learn about how to utilize multiple evaluation techniques in carotid artery stenosis patients for optimizing assessment of diagnosis and treatment strategy.\n\nThe main questions it aims to answer are:\n\n* Identify best strategy that use multi-modal MRI and CT to assess patients' cerebral lesions and perfusion.\n* Identify best strategy that use multi-modal MRI, PET-MRI ultrasound and CT to assess components and characters of patients' carotid plaques.\n\nParticipants will accept imaging examination before and after surgery. And doctors will collect basic characteristics, imaging results and biological samples of patients for analysis.",[106],"Carotid Artery Stenosis",[108,109,110,111,112,36,40],"carotid artery stenosis","Perfusion","plaque","MRI","CT","2022-11-28",{"date":115,"type":116},"2022-11-29","ACTUAL",{"date":118,"type":116},"2015-01-01",{"date":120,"type":102},"2026-12-31",{"name":5,"class":6},1]