[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100575167":3},{"organization":4,"armGroups":7,"interventions":78,"overallOfficials":101,"centralContacts":108,"locations":117,"responsibleParty":134,"collaborators":137,"id":141,"slug":142,"hasResults":143,"nctId":144,"briefTitle":145,"officialTitle":145,"acronym":146,"eligibilityCriteria":147,"healthyVolunteers":143,"sex":148,"minAge":149,"maxAge":84,"enrollmentInfo":150,"targetDuration":84,"studyType":153,"phases":154,"briefSummary":156,"conditions":157,"keywords":159,"overallStatus":119,"whyStopped":84,"lastUpdateSubmitDate":163,"lastUpdatePostDateStruct":164,"startDateStruct":167,"completionDateStruct":169,"leadSponsor":171,"locationsCount":172},{"fullName":5,"class":6},"University of South Carolina","OTHER",[8,18,22,26,30,34,38,42,46,50,54,58,62,66,70,74],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental condition 1","EXPERIMENTAL","Energize Online Program plus phone coaching, progress reports to physicians, 'Hear From Others' videos, and individualized feedback",[13,14,15,16,17],"Behavioral: Phone Coaching","Behavioral: Progress reports to providers","Behavioral: 'Hear from Others' Videos","Behavioral: Individualized Feedback","Behavioral: Online exercise program",{"label":19,"type":10,"description":20,"interventionNames":21},"Experimental condition 2","Energize Online Program plus phone coaching, progress reports to physicians, and 'Hear From Others' videos",[13,14,15,17],{"label":23,"type":10,"description":24,"interventionNames":25},"Experimental condition 3","Energize Online Program plus phone coaching, progress reports to physicians, and individualized feedback",[13,14,16,17],{"label":27,"type":10,"description":28,"interventionNames":29},"Experimental condition 4","Energize Online Program plus phone coaching and progress reports to physicians",[13,14,17],{"label":31,"type":10,"description":32,"interventionNames":33},"Experimental condition 5","Energize Online Program plus phone coaching, 'Hear From Others' videos, and individualized feedback",[13,15,16,17],{"label":35,"type":10,"description":36,"interventionNames":37},"Experimental condition 6","Energize Online Program plus phone coaching and 'Hear From Others' videos",[13,15,17],{"label":39,"type":10,"description":40,"interventionNames":41},"Experimental condition 7","Energize Online Program plus phone coaching and individualized feedback",[13,16,17],{"label":43,"type":10,"description":44,"interventionNames":45},"Experimental condition 8","Energize Online Program plus phone coaching",[13,17],{"label":47,"type":10,"description":48,"interventionNames":49},"Experimental condition 9","Energize Online Program plus progress reports to physicians, 'Hear From Others' videos, and individualized feedback",[14,15,16,17],{"label":51,"type":10,"description":52,"interventionNames":53},"Experimental condition 10","Energize Online Program plus progress reports to physicians and 'Hear From Others' videos",[14,15,17],{"label":55,"type":10,"description":56,"interventionNames":57},"Experimental condition 11","Energize Online Program plus progress reports to physicians and individualized feedback",[14,16,17],{"label":59,"type":10,"description":60,"interventionNames":61},"Experimental condition 12","Energize Online Program plus progress reports to physicians",[14,17],{"label":63,"type":10,"description":64,"interventionNames":65},"Experimental condition 13","Energize Online Program plus 'Hear From Others' videos and individualized feedback",[15,16,17],{"label":67,"type":10,"description":68,"interventionNames":69},"Experimental condition 14","Energize Online Program plus 'Hear From Others' videos",[15,17],{"label":71,"type":10,"description":72,"interventionNames":73},"Experimental condition 15","Energize Online Program plus individualized feedback",[16,17],{"label":75,"type":10,"description":76,"interventionNames":77},"Experimental condition 16","Energize Online Program",[17],[79,85,89,93,97],{"type":80,"name":81,"description":82,"armGroupLabels":83,"otherNames":84},"BEHAVIORAL","Phone Coaching","Participants will receive 11 coaching calls with a health coach. Calls will occur weekly during the first month, twice\u002Fmonth during months 2-3, and once\u002Fmonth during months 4-6. Each call is expected to last 10-15 minutes.",[9,19,23,27,31,35,39,43],null,{"type":80,"name":86,"description":87,"armGroupLabels":88,"otherNames":84},"Progress reports to providers","Progress reports on physical activity and program adherence will be sent to participants providers at 3 and 6 months.",[9,51,55,59,19,23,27,47],{"type":80,"name":90,"description":91,"armGroupLabels":92,"otherNames":84},"'Hear from Others' Videos","Participants will receive monthly 'Hear From Others' videos. The videos will include other adults with knee replacement discussing the challenges they have faced and strategies to overcome barriers to activity.",[9,51,63,67,19,31,35,47],{"type":80,"name":94,"description":95,"armGroupLabels":96,"otherNames":84},"Individualized Feedback","Participants will receive individualized feedback from a coach via email. The feedback will specifically focus on participant responses to the 'Apply Your Knowledge' activities and will correspond with the video lessons. Feedback will be weekly during months 1-3 and monthly during months 4-6.",[9,55,63,71,23,31,39,47],{"type":80,"name":98,"description":99,"armGroupLabels":100,"otherNames":84},"Online exercise program","MOST Energized! Online Exercise Program",[9,51,55,59,63,67,71,75,19,23,27,31,35,39,43,47],[102,105],{"name":103,"affiliation":5,"role":104},"Christine Pellegrini, PhD","PRINCIPAL_INVESTIGATOR",{"name":106,"affiliation":107,"role":104},"Jessica Unick, PhD","The Miriam Hospital",[109,114],{"name":110,"role":111,"phone":112,"phoneExt":84,"email":113},"Jakob Nelson, MS","CONTACT","803-766-6960","JAKOBRN@email.sc.edu",{"name":103,"role":111,"phone":115,"phoneExt":84,"email":116},"803-777-0911","pellegca@mailbox.sc.edu",[118],{"facility":5,"status":119,"city":120,"state":121,"zip":122,"country":123,"countryCode":124,"cosmosGeoPoint":125,"geoPoint":130,"contacts":131},"RECRUITING","Columbia","South Carolina","29208","United States","US",{"type":126,"coordinates":127},"Point",[128,129],-81.03481,34.00071,{"lat":129,"lon":128},[132],{"name":133,"role":111,"phone":115,"phoneExt":84,"email":116},"Christine Pellegrini",{"type":104,"investigatorFullName":135,"investigatorTitle":136,"investigatorAffiliation":5,"oldNameTitle":84,"oldOrganization":84},"Christine A Pellegrini, PhD","Associate Professor",[138],{"name":139,"class":140},"National Institute on Aging (NIA)","NIH","100575167","optimizing-a-remote-based-physical-activity-intervention-for-adults-with-total-knee-replacement-100575167",false,"NCT06768762","Optimizing a Remote-based Physical Activity Intervention for Adults With Total Knee Replacement","MOST Energized","Inclusion Criteria:\n\n* had a knee replacement (including primary, staged or independent bilateral, or revision) at least 12 months ago\n* have a computer, tablet, or smartphone with active internet access\n* self-report engaging in less than 60 minutes\u002Fweek of moderate-intensity physical activity\n* be English-speaking and able to read consent and study materials written in English\n* be willing to complete the 4 remote assessments, including physical activity monitoring\n* be willing to be randomized to receive 0-4 supplemental intervention components.\n\nExclusion Criteria:\n\n* any contraindications to physical activity (e.g., chest pain)\n* have a scheduled surgery within the next 12 months (e.g., hip or knee replacement)\n* have a mobility limiting comorbidity unrelated to knee replacement\n* live outside of the continental U.S\n* do not currently have a physician or orthopedic surgeon whom they see regularly\n* are currently participating in physical therapy (for knee)\n* are participating in a structured weight loss or physical activity program\n* unable to provide proof of knee replacement surgery\n* have a BMI \\>40kg\u002Fm2\n* score \\>30 on PROMIS cognitive function","ALL","18 Years",{"count":151,"type":152},336,"ESTIMATED","INTERVENTIONAL",[155],"NA","The purpose of this study is to identify which supplemental intervention components added to an online exercise program contribute to the greatest increases in physical activity (total MVPA and percent meeting guidelines \\[≥150 min\u002Fweek of MVPA\\]) in adults with knee replacement at 6 and 12 months. Secondary outcomes will examine changes in pain and physical function.",[158],"Knee Replacement",[160,161,162],"knee replacement","exercise","online","2026-04-28",{"date":165,"type":166},"2026-05-05","ACTUAL",{"date":168,"type":166},"2025-01-21",{"date":170,"type":152},"2029-07-31",{"name":5,"class":6},1]