[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100589223":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":32,"locations":38,"responsibleParty":60,"collaborators":63,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":24,"eligibilityCriteria":73,"healthyVolunteers":69,"sex":74,"minAge":75,"maxAge":24,"enrollmentInfo":76,"targetDuration":24,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":86,"overallStatus":41,"whyStopped":24,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"University of Vermont Medical Center","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention Group","EXPERIMENTAL","Patients who recently experienced a myocardial infarction (MI) or percutaneous intervention (PCI; angioplasty, stent placement or valve replacement) and enroll in Phase 2 Cardiac Rehabilitation (CR) may be randomized to High intensity training",[13],"Other: HIIT",{"label":15,"type":10,"description":16,"interventionNames":17},"Usual Care Group","Patients who recently experienced a myocardial infarction (MI) or percutaneous intervention (PCI; angioplasty, stent placement or valve replacement) and enroll in Phase 2 Cardiac Rehabilitation (CR) may be randomized to Moderate intensity training",[18],"Other: MICT",[20,25],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"HIIT","Patients who recently experienced a myocardial infarction (MI) or percutaneous intervention (PCI; angioplasty, stent placement or valve replacement) and enroll in Phase 2 Cardiac Rehabilitation (CR) may be randomized to High intensity training (HIIT)",[9],null,{"type":6,"name":26,"description":16,"armGroupLabels":27,"otherNames":24},"MICT",[15],[29],{"name":30,"affiliation":5,"role":31},"Sherrie Khadanga MD, Principal Investigator, MD","PRINCIPAL_INVESTIGATOR",[33],{"name":34,"role":35,"phone":36,"phoneExt":24,"email":37},"Patrick Savage, Research Coordinator","CONTACT","802-847-4545","patrick.savage@uvmhealth.org",[39],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"UVMMC Cardiac Rehabilitation","RECRUITING","South Burlington","Vermont","05403","United States","US",{"type":48,"coordinates":49},"Point",[50,51],-73.17096,44.46699,{"lat":51,"lon":50},[54,58],{"name":55,"role":35,"phone":56,"phoneExt":24,"email":57},"Sheena Barnes Clinic Supervisor","802-847-4600","sheena.barnes@uvmhealth.org",{"name":59,"role":31,"phone":24,"phoneExt":24,"email":24},"Sherrie Khadanga PI, MD",{"type":31,"investigatorFullName":61,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Sherrie Khadanga","Principal Investigator",[64],{"name":65,"class":66},"National Institute on Aging (NIA)","NIH","100589223","optimizing-aerobic-fitness-in-older-adults-100589223",false,"NCT06951620","Optimizing Aerobic Fitness in Older Adults","Optimizing Aerobic Fitness and Functional Response to Exercise in Older Adults","Inclusion Criteria:\n\n* \\>65 years old\n* ambulatory\n* enrolled in CR at our center following a recent clinical diagnosis of myocardial infarction or percutaneous intervention will be recruited\n\nExclusion Criteria:\n\n* have an active malignancy (excluding non-melanoma skin cancer or low grade prostate cancer under surveillance)\n* unwilling to comply with the exercise prescription they may be assigned to\n* have a submaximal performance on entry exercise tolerance test, defined as respiratory exchange ratio \\\u003C1.0","ALL","65 Years",{"count":77,"type":78},114,"ESTIMATED","INTERVENTIONAL",[81],"NA","Hospitalization and treatment for cardiovascular disease is one of the main contributors to disability in older adults. Moderate intensity continuous aerobic and resistance training have been the cornerstone of cardiac rehabilitation (CR) for decades to remediate hospital-acquired functional deficits, but some groups receive less or minimal functional benefit from this training. The proposed studies seek to optimize recovery of aerobic fitness and physical function among older cardiac patients using a novel high intensity training regimen with the long-term goal of reducing subsequent disability and improving clinical outcomes.",[84,85],"Aerobic Capacity","High Intensity Interval Training",[87,21,26,88,89],"cardiac rehabilitation","exercise in older adults","aerobic capacity","2025-06-06",{"date":92,"type":93},"2025-06-08","ACTUAL",{"date":95,"type":93},"2025-04-17",{"date":97,"type":78},"2029-06-30",{"name":5,"class":6},1]