[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100554594":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":29,"centralContacts":33,"locations":39,"responsibleParty":54,"collaborators":23,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":60,"acronym":23,"eligibilityCriteria":61,"healthyVolunteers":58,"sex":62,"minAge":63,"maxAge":23,"enrollmentInfo":64,"targetDuration":23,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":23,"overallStatus":42,"whyStopped":23,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"University of Colorado, Denver","OTHER",[8,13],{"label":9,"type":6,"description":10,"interventionNames":11},"Educational intervention","SP02 target ranges will be 90-96%. Education about the specific oxygen targets will be provided to the clinical teams. Real time feedback on adherence to the Sp02 target range will be provided by virtual respiratory therapists.",[12],"Other: Education",{"label":14,"type":6,"description":15,"interventionNames":16},"Educational intervention Epic alert","An education-based intervention that also focuses on mitigating Occult Hypoxemia in mechanically ventilated patients, and thus utilizes the same patient population. The second intervention will notify the clinical team to an abnormal laboratory result in real time. This laboratory result is already located in the patient's Epic chart under arterial blood gas (ABG), arterial oxygen saturation (Sa02) Patient level randomization will occur in Epic as\n\n1. alert (notification) the providers of sustained occult hypoxemia or\n2. silent alert The investigators are observing physician behavior in response to alerting them that a patient has occult hypoxemia via an Epic alert.",[17],"Behavioral: Epic notification alert",[19,24],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":23},"Education","1\\) Standardized materials to discuss the rationale and procedural aspects of the intervention, including details on the specific oxygen target-related modifications to the mechanical ventilation order-set prior to starting the intervention phase.",[9],null,{"type":25,"name":26,"description":27,"armGroupLabels":28,"otherNames":23},"BEHAVIORAL","Epic notification alert","An education-based intervention that focuses on mitigating Occult Hypoxemia in mechanically ventilated patients and thus utilizes the same patient population. The second intervention will notify the clinical team to an abnormal laboratory result in real time. This laboratory result is already located in the patient's Epic chart under arterial blood gas (ABG), arterial oxygen saturation (Sa02) Patient level randomization will occur in Epic to as\n\n1. alert (notification) the providers of sustained occult hypoxemia\n2. silent alert",[14],[30],{"name":31,"affiliation":5,"role":32},"Neil Aggarwal, MD","PRINCIPAL_INVESTIGATOR",[34],{"name":35,"role":36,"phone":37,"phoneExt":23,"email":38},"Carrie Higgins, BSN","CONTACT","720-560-3037","carrie.higgins@cuanschutz.edu",[40],{"facility":41,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":23},"University of Colorado","RECRUITING","Aurora","Colorado","80045","United States","US",{"type":49,"coordinates":50},"Point",[51,52],-104.83192,39.72943,{"lat":52,"lon":51},{"type":55,"investigatorFullName":23,"investigatorTitle":23,"investigatorAffiliation":23,"oldNameTitle":23,"oldOrganization":23},"SPONSOR","100554594","optimizing-care-in-critically-ill-at-uchealth-by-liberalizing-the-target-o2-in-mechanically-ventilated-icu-patients-100554594",false,"NCT06501118","Optimizing Care in Critically Ill at UCHealth by Liberalizing the Target O2 in Mechanically-ventilated ICU Patients","Inclusion Criteria:\n\n* Admission to ICU and requiring invasive mechanical ventilation\n\nExclusion Criteria:\n\n* Transferred patients from outside the UCHealth system\\*:\n* Patients with pre-existing disease that requires chronic use of positive pressure ventilation delivered through a tracheostomy\\*:\n* Pregnant women:\n* Prisoners\n* Patients receiving mechanical ventilation for less than twelve hours","ALL","18 Years",{"count":65,"type":66},3600,"ESTIMATED","INTERVENTIONAL",[69],"NA","A multimodal educational intervention to target an oxygen saturation target range (SpO2 90-96%) will reduce ventilator length of stay and reduce occult hypoxemia by increased awareness and adherence to a designated oxygen saturation target range.",[72,73,74,75,76,77],"Respiratory Failure","Acute Hypoxemic Respiratory Failure","Acute Hypoxic Respiratory Failure","Hypoxemia","Hypoxia","Hypoxic Respiratory Failure","2026-05-04",{"date":80,"type":81},"2026-05-08","ACTUAL",{"date":83,"type":81},"2024-09-01",{"date":85,"type":66},"2026-07-31",{"name":5,"class":6},1]