[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100641562":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":36,"locations":45,"responsibleParty":80,"collaborators":83,"id":86,"slug":87,"hasResults":88,"nctId":89,"briefTitle":90,"officialTitle":91,"acronym":92,"eligibilityCriteria":93,"healthyVolunteers":88,"sex":94,"minAge":95,"maxAge":25,"enrollmentInfo":96,"targetDuration":25,"studyType":99,"phases":100,"briefSummary":102,"conditions":103,"keywords":106,"overallStatus":111,"whyStopped":25,"lastUpdateSubmitDate":112,"lastUpdatePostDateStruct":113,"startDateStruct":116,"completionDateStruct":118,"leadSponsor":120,"locationsCount":121},{"fullName":5,"class":6},"University of California, San Diego","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"E-CBSST","EXPERIMENTAL","E-CBSST is the experimental arm in this study.",[13],"Behavioral: E-CBSST",{"label":15,"type":16,"description":17,"interventionNames":18},"E-SC","ACTIVE_COMPARATOR","E-SC is the comparator condition in this study.",[19],"Behavioral: E-SC",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","E-CBSST is a blended, in-person intervention that combines components of Executive Function Training (EFT) with Cognitive Behavioral Social Skills Training (CBSST). Participants complete 6 sessions of EFT and then 36 sessions of combined EFT and CBSST. CBSST techniques are based on cognitive behavioral therapy and social skills training developed for adult patients with schizophrenia. Participants set meaningful recovery goals and then learn skills to achieve their goals.",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"E-SC is a goal-focused supportive contact group therapy intervention that provides the same frequency and amount of therapist and other group member contact as E-CBSST. Participants will complete the same number of EFT sessions and then continue with semi-structured supportive contact sessions of the same number and duration as participants in the E-CBSST arm. The SC intervention will have a primary focus on setting and achieving recovery goals (e.g., living, learning, and socializing).",[15],[30,33],{"name":31,"affiliation":5,"role":32},"Eric Granholm, PhD","PRINCIPAL_INVESTIGATOR",{"name":34,"affiliation":35,"role":32},"Tarek Rajji, MD","UT Southwestern",[37,42],{"name":38,"role":39,"phone":40,"phoneExt":25,"email":41},"Jason Holden, PhD","CONTACT","858-246-2517","jlholden@health.ucsd.edu",{"name":31,"role":39,"phone":43,"phoneExt":25,"email":44},"858-534-2542","egranholm@health.ucsd.edu",[46,62],{"facility":5,"status":25,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"San Diego","California","92093","United States","US",{"type":53,"coordinates":54},"Point",[55,56],-117.16472,32.71571,{"lat":56,"lon":55},[59,60,61],{"name":38,"role":39,"phone":40,"phoneExt":25,"email":41},{"name":31,"role":39,"phone":43,"phoneExt":25,"email":44},{"name":31,"role":32,"phone":25,"phoneExt":25,"email":25},{"facility":63,"status":25,"city":64,"state":65,"zip":66,"country":50,"countryCode":51,"cosmosGeoPoint":67,"geoPoint":71,"contacts":72},"UT Southwestern Medical Center","Dallas","Texas","75390",{"type":53,"coordinates":68},[69,70],-96.80667,32.78306,{"lat":70,"lon":69},[73,77],{"name":74,"role":39,"phone":75,"phoneExt":25,"email":76},"Farra Kahalnik, MPH, MSSW","214-645-6954","Farra.Kahalnik@UTSouthwestern.edu",{"name":34,"role":39,"phone":78,"phoneExt":25,"email":79},"214-648-4947","Tarek.Rajji@UTSouthwestern.edu",{"type":32,"investigatorFullName":81,"investigatorTitle":82,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Eric Granholm","Professor",[84],{"name":85,"class":6},"University of Texas Southwestern Medical Center","100641562","optimizing-cbsst-with-executive-function-training-for-schizophrenia-r33-100641562",false,"NCT07658391","Optimizing CBSST With Executive Function Training for Schizophrenia (R33)","Optimizing Cognitive Behavioral Social Skills Training With Executive Function Training for Older Adults With Schizophrenia","ECBSST R33","Inclusion Criteria:\n\n1. Voluntary informed consent to participate;\n2. Age 60 years or older;\n3. DSM-5 diagnosis of schizophrenia or schizoaffective disorder based on the SCID;\n4. Be clinically stable as operationalized by (1) not having been admitted to a psychiatric hospital within the three months prior to assessment, (2) having had no change in antipsychotic medication dosage within four weeks prior to the baseline assessment, and (3) and ascertained to be clinically and medically stable by one the study investigators;\n5. Be willing and able to speak English;\n6. Be able to read and converse (with corrected vision or hearing if needed).\n\nExclusion Criteria:\n\n1. Meets criteria for a cognitive disorder or for a neurological or other medical disorder affecting the ability to participate in Executive Function Training or CBSST;\n2. Meets diagnostic criteria for bipolar disorder, current major depressive episode, or substance abuse or dependence within the six months prior to the baseline assessment except for caffeine or nicotine;\n3. Received electroconvulsive therapy within six months of the baseline assessment.","ALL","60 Years",{"count":97,"type":98},106,"ESTIMATED","INTERVENTIONAL",[101],"NA","This randomized controlled clinical trial will test a blended intervention that combines Executive Function Training with Cognitive-Behavioral Skills Training (E-CBSST). E-CBSST will be delivered to adults with late-life schizophrenia to determine if it increases Cognitive Behavioral Social Skills Training skills learning more than a supportive contact control condition and leads to improved functioning.",[104,105],"Schizophrenia","Schizoaffective Disorder",[104,107,108,109,110],"serious mental illness","randomized clinical trial","executive function training","Cognitive Behavioral Social Skills Training","NOT_YET_RECRUITING","2026-06-18",{"date":114,"type":115},"2026-06-23","ACTUAL",{"date":117,"type":98},"2026-10-01",{"date":119,"type":98},"2029-06",{"name":5,"class":6},2]