[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100631595":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":10,"locations":10,"responsibleParty":15,"collaborators":19,"id":41,"slug":42,"hasResults":43,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":10,"eligibilityCriteria":47,"healthyVolunteers":43,"sex":48,"minAge":49,"maxAge":10,"enrollmentInfo":50,"targetDuration":53,"studyType":54,"phases":10,"briefSummary":55,"conditions":56,"keywords":10,"overallStatus":61,"whyStopped":10,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":10},{"fullName":5,"class":6},"Shanghai Zhongshan Hospital","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"TIPS treatment group",null,"The patient underwent Transjugular Intrahepatic Portosystemic Shunt (TIPS) after admission",{"label":13,"type":10,"description":14,"interventionNames":10},"Endoscopic treatment group","The patient only received endoscopic treatment after admission.",{"type":16,"investigatorFullName":17,"investigatorTitle":18,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Shiyao Chen","Professor",[20,22,25,27,29,31,33,35,37,39],{"name":21,"class":6},"RenJi Hospital",{"name":23,"class":24},"Shandong Provincial Hospital","OTHER_GOV",{"name":26,"class":6},"Qilu Hospital of Shandong University",{"name":28,"class":6},"Third Affiliated Hospital, Sun Yat-Sen University",{"name":30,"class":6},"Nanfang Hospital, Southern Medical University",{"name":32,"class":6},"The First Affiliated Hospital of Nanchang University",{"name":34,"class":6},"Shanghai East Hospital",{"name":36,"class":6},"Shanghai Changzheng Hospital",{"name":38,"class":6},"Second Military Medical University",{"name":40,"class":6},"The General Hospital of Northern Theater Command","100631595","optimizing-endoscopic-and-interventional-treatment-for-portal-hypertensive-bleeding-100631595",false,"NCT07502729","Optimizing Endoscopic and Interventional Treatment for Portal Hypertensive Bleeding","Improve the Strategies of Endoscopic and Interventional Treatment of Gastroesophageal Hemorrhage in Portal Hypertension","Inclusion Criteria:\n\n* Admitted due to gastrointestinal bleeding and clinically diagnosed with portal hypertension\n* Underwent imaging examinations and gastroscopy within one week after admission\n* Gastroscopy revealed the presence of esophageal and\u002For gastric varices\n* Age over 18 years\n\nExclusion Criteria:\n\n* Previous history of liver transplantation\n* Imaging or gastroscopy findings indicated ulcers or other causes of gastrointestinal bleeding\n* Concurrent severe life-threatening diseases involving the circulatory, hematological, or respiratory systems\n* Difficulty in follow-up, or lack of essential medical history information, imaging data, or other necessary records","ALL","18 Years",{"count":51,"type":52},1066,"ESTIMATED","12 Months","OBSERVATIONAL","This study aims to evaluate the impact of high-risk factors-such as elevated portal venous pressure, concurrent large extra-luminal vessels, portal vein thrombosis, and prominent portosystemic shunts-on the efficacy of endoscopic therapy. By comparing with interventional treatment, the goal is to optimize the clinical management protocol for esophageal and gastric varices, enhance the therapeutic outcomes of portal hypertension-related esophageal and gastric varices, and improve patient prognosis.",[57,58,59,60],"Portal Hypertension","Gastroesophageal Varices Hemorrhage","Gastric Varices","Esophageal Varices","NOT_YET_RECRUITING","2026-03-24",{"date":64,"type":65},"2026-03-31","ACTUAL",{"date":67,"type":52},"2026-03-17",{"date":69,"type":52},"2027-12-31",{"name":5,"class":6}]