[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100362134":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":40,"centralContacts":45,"locations":55,"responsibleParty":94,"collaborators":31,"id":96,"slug":97,"hasResults":98,"nctId":99,"briefTitle":100,"officialTitle":101,"acronym":102,"eligibilityCriteria":103,"healthyVolunteers":98,"sex":104,"minAge":105,"maxAge":106,"enrollmentInfo":107,"targetDuration":31,"studyType":110,"phases":111,"briefSummary":113,"conditions":114,"keywords":118,"overallStatus":57,"whyStopped":31,"lastUpdateSubmitDate":123,"lastUpdatePostDateStruct":124,"startDateStruct":127,"completionDateStruct":129,"leadSponsor":131,"locationsCount":132},{"fullName":5,"class":6},"VA Office of Research and Development","FED",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Error-augmentation training","EXPERIMENTAL","A 4-week, 8 session, treadmill-based gait training program, with error-augmentation of step asymmetry delivered on a split-belt treadmill. Each training session will adhere to the same schedule. During the training blocks on the treadmill, the belt under the limb with the shorter step length will be set at 3\u002F4 of the pre-intervention over-ground self-selected walking speed while the belt under the limb with the longer step length will be set to 1\u002F2 of the fast belt speed (2:1 ratio between belts).",[13],"Behavioral: Error-augmentation gait training",{"label":15,"type":10,"description":16,"interventionNames":17},"Error-correction training","A 4-week, 8 session, treadmill-based gait training program, with error-correction of step asymmetry delivered with an auditory metronome signal while walking on a treadmill. During each training block, the metronome will be set to overcorrect stance time asymmetry through use of asymmetrical metronome tones, 2:1 ratio.",[18],"Behavioral: Error-correction gait training",{"label":20,"type":21,"description":22,"interventionNames":23},"Supervised waking","ACTIVE_COMPARATOR","A 4-week, 8 session, treadmill-based supervised walking program. The active comparator group will participate in a supervised treadmill walking program of the same frequency and duration, to the two experimental groups.",[24],"Behavioral: Supervised walking",[26,32,36],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"BEHAVIORAL","Error-augmentation gait training","Split-belt treadmill training to enhance between-limb asymmetry during treadmill walking, which is intended to force compensation and correction of step asymmetry during treadmill walking. The error-augmentation gait training program is delivered in 8 sessions over 4 weeks.",[9],null,{"type":27,"name":33,"description":34,"armGroupLabels":35,"otherNames":31},"Error-correction gait training","Metronome will be set to cue participants to overcorrect between-limb step asymmetry during treadmill walking, through use of asymmetrical metronome tones in a 2:1 ratio. The error-correction gait training program is delivered in 8 sessions over 4 weeks.",[15],{"type":27,"name":37,"description":38,"armGroupLabels":39,"otherNames":31},"Supervised walking","An active comparator intervention, in which a supervised treadmill walking program is delivered without attempt to correct step asymmetry. The supervised walking program is delivered in 8 sessions over 4 weeks.",[20],[41],{"name":42,"affiliation":43,"role":44},"Cory L. Christiansen, PhD","Rocky Mountain Regional VA Medical Center, Aurora, CO","PRINCIPAL_INVESTIGATOR",[46,51],{"name":47,"role":48,"phone":49,"phoneExt":31,"email":50},"Cory L Christiansen, PhD","CONTACT","(303) 724-9101","Cory.Christiansen@va.gov",{"name":52,"role":48,"phone":53,"phoneExt":31,"email":54},"Ryan Stephenson, DO","(303) 399-8020","ryan.stephenson@va.gov",[56,77],{"facility":43,"status":57,"city":58,"state":59,"zip":60,"country":61,"countryCode":62,"cosmosGeoPoint":63,"geoPoint":68,"contacts":69},"RECRUITING","Aurora","Colorado","80045-7211","United States","US",{"type":64,"coordinates":65},"Point",[66,67],-104.83192,39.72943,{"lat":67,"lon":66},[70,72,76],{"name":52,"role":48,"phone":71,"phoneExt":31,"email":54},"303-399-8020",{"name":73,"role":48,"phone":74,"phoneExt":31,"email":75},"Thomas Fields, DPT","(720) 723-3372","thomas.fields@va.gov",{"name":42,"role":44,"phone":31,"phoneExt":31,"email":31},{"facility":78,"status":57,"city":79,"state":80,"zip":81,"country":61,"countryCode":62,"cosmosGeoPoint":82,"geoPoint":86,"contacts":87},"Hunter Holmes McGuire VA Medical Center, Richmond, VA","Richmond","Virginia","23249",{"type":64,"coordinates":83},[84,85],-77.46026,37.55376,{"lat":85,"lon":84},[88,91],{"name":89,"role":48,"phone":31,"phoneExt":31,"email":90},"John Hermanson, MD","john.hermanson@va.gov",{"name":92,"role":48,"phone":31,"phoneExt":31,"email":93},"Benjamin Darter, DPT","benjamin.darter@va.gov",{"type":95,"investigatorFullName":31,"investigatorTitle":31,"investigatorAffiliation":31,"oldNameTitle":31,"oldOrganization":31},"SPONSOR","100362134","optimizing-gait-rehabilitation-for-veterans-with-non-traumatic-lower-limb-amputation-100362134",false,"NCT03995238","Optimizing Gait Rehabilitation for Veterans With Non-traumatic Lower Limb Amputation","Optimizing Gait Rehabilitation for Veterans With Non-Traumatic Lower Limb Amputation","GEM","Inclusion Criteria:\n\n* Unilateral, non-traumatic, transtibial amputation\n* Diabetes mellitus and\u002For peripheral artery disease\n* Able to ambulate in the community without assistive device\n* Step length asymmetry during walking (\\>1.0 asymmetry index.)\n* 6 months since amputation\n\nExclusion Criteria:\n\n* Unstable heart condition\n* Including unstable angina, uncontrolled cardiac dysrhythmia, acute myocarditis, hypertension, and acute pericarditis\n* Acute systemic infection\n* Active cancer treatment\n* Traumatic or cancer related amputation etiology","ALL","40 Years","89 Years",{"count":108,"type":109},54,"ESTIMATED","INTERVENTIONAL",[112],"NA","The population of older Veterans with non-traumatic lower limb amputation is growing. Following lower limb amputation, asymmetrical movements persist during walking and likely contribute to disabling sequelae including secondary pain conditions, poor gait efficiency, impaired physical function, and compromised skin integrity of the residual limb. This study seeks to address chronic gait asymmetry by evaluating the efficacy of two error-manipulation gait training programs to improve gait symmetry for Veterans with non-traumatic lower limb amputation. Additional this study will evaluate the potential of error-manipulation training programs to improve secondary measures of disability and residual limb skin health. Ultimately, this study aims to improve conventional prosthetic rehabilitation for Veterans with non-traumatic amputation through gait training programs based in motor learning principles, resulting in improved gait symmetry and lower incidence of long-term disability after non-traumatic lower limb amputation.",[115,116,117],"Transtibial Amputation","Peripheral Artery Disease","Diabetes Mellitus",[119,120,121,122,116],"Amputation","Rehabilitation","Gait Training","Diabetes","2026-04-06",{"date":125,"type":126},"2026-04-13","ACTUAL",{"date":128,"type":126},"2019-10-09",{"date":130,"type":109},"2026-10-31",{"name":5,"class":6},2]